DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bsh and Dlx5

DIOPT Version :9

Sequence 1:	NP_477350.2	Gene:	bsh / 35266	FlyBaseID:	FBgn0000529	Length:	429	Species:	Drosophila melanogaster
Sequence 2:	NP_034186.2	Gene:	Dlx5 / 13395	MGIID:	101926	Length:	289	Species:	Mus musculus

Alignment Length:	279	Identity:	77/279 - (27%)
Similarity:	110/279 - (39%)	Gaps:	94/279 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   163 DQISQQLGSGAAQHP-PVPTTQPQPPPPPPLNGGSGASNGVLYPNAPYTDHGFLQMTLGYLSPSS 226
            |:....:.||..|.| |.......|....|....|.|::...|..|....|       ||.||:|
Mouse     6 DRRVPSIRSGDFQAPFPTSAAMHHPSQESPTLPESSATDSDYYSPAGAAPH-------GYCSPTS 63

  Fly   227 GTY-KSVDPY-----------------------FLSQASLFGGAPFFGAPGCV---------PEL 258
            .:| |:::||                       :.|....:||| :...|...         ||:
Mouse    64 ASYGKALNPYQYQYHGVNGSAAGYPAKAYADYGYASPYHQYGGA-YNRVPSATSQPEKEVAEPEV 127

  Fly   259 ALGLGMGVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQ 323
            .:     ||. :..:.||.||::|..||:.|::||:..:||:.|||.|||.:|||::||||.|||
Mouse   128 RM-----VNG-KPKKVRKPRTIYSSFQLAALQRRFQKTQYLALPERAELAASLGLTQTQVKIWFQ 186

  Fly   324 NRRMKHKKQLRRRDNANEPVDFSRSEPGKQPGEATSSSGD----------------------SKH 366
            |:|.|.||.::.               |:.|.|.:.||.|                      |.|
Mouse   187 NKRSKIKKIMKN---------------GEMPPEHSPSSSDPMACNSPQSPAVWEPQGSSRSLSHH 236

  Fly   367 GKLNPGSVGGTPTQPTSEQ 385
            ...:|         |||.|
Mouse   237 PHAHP---------PTSNQ 246

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeobox	278..330	CDD:278475	29/51 (57%)
Dlx5	NP_034186.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..49		10/42 (24%)
		DLL_N	32..118	CDD:403572	20/93 (22%)
		Homeobox	140..194	CDD:395001	29/53 (55%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	198..253		13/73 (18%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	270..289
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D574097at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920