Protein Alignment bsh and Cdx1

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_034010.3
• Gene: Cdx1 / 12590
• MGIID: 88360
• Length: 268
• Species: Mus musculus
• Alignment Length: 284
• Identity: 80/284 - (28%)
• Similarity: 103/284 - (36%)
• Gaps: 86/284 - (30%)

  Fly   160 YNGDQISQQLGSGAAQH-PPVPT--------------TQPQPPPPP------------------P 191
            |.|......||.|...: ||.|.              .:|.|.|||                  |
Mouse    14 YPGPARPSSLGLGPPTYAPPGPAPAPPQYPDFAGYTHVEPAPAPPPTWAAPFPAPKDDWAAAYGP 78

  Fly   192 LNGGSGASNGVL----------YPNAPYTDHGFLQMTLGYLSPSSGTYKSVDPYFLSQASLFGGA 246
            ....|.||...|          .|..|....|.|..:||  :|                    ||
Mouse    79 GPTASAASPAPLAFGPPPDFSPVPAPPGPGPGILAQSLG--AP--------------------GA 121

  Fly   247 PFF-GAPGCVP------ELALGLGMGVNALRHCRRRKARTVFSDPQLSGLEKRFEGQRYLSTPER 304
            |.. |||...|      .:|...|.|....|  .:.|.|.|::|.|...|||.|...||::...:
Mouse   122 PSSPGAPRRTPYEWMRRSVAAAGGGGSGKTR--TKDKYRVVYTDHQRLELEKEFHYSRYITIRRK 184

  Fly   305 VELATALGLSETQVKTWFQNRRMKHKKQLRRRDNANEPVDFSRSEPGKQ---PGEATSSSGDSKH 366
            .|||..|||:|.|||.||||||.|.:|..:::....:|:      |..|   |.:.|.:......
Mouse   185 SELAANLGLTERQVKIWFQNRRAKERKVNKKKQQQQQPL------PPTQLPLPLDGTPTPSGPPL 243

  Fly   367 GKLNPGSVG--GTPTQ-PTSEQQL 387
            |.|.|.:.|  |||:. |..|:.|
Mouse   244 GSLCPTNAGLLGTPSPVPVKEEFL 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	28/55 (51%)
Cdx1	NP_034010.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..152		35/159 (22%)
		Caudal_act	13..140	CDD:461413	32/147 (22%)
		Homeodomain	156..211	CDD:459649	28/54 (52%)
		Interaction with DNA. /evidence=ECO:0000250|UniProtKB:P47902	157..178		8/20 (40%)
		Interaction with 5-mCpG DNA. /evidence=ECO:0000250|UniProtKB:P47902	196..207		8/10 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	209..268		16/65 (25%)