Protein Alignment bsh and DBX1

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_001025036.2
• Gene: DBX1 / 120237
• HGNCID: 33185
• Length: 343
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 86/329 - (26%)
• Similarity: 120/329 - (36%)
• Gaps: 98/329 - (29%)

  Fly   165 ISQQLGSGAAQH-------------PP------VPTTQPQPP---PPPPL---------NGGSGA 198
            :.|.|.|..:.|             ||      |||....||   .|..|         :.|.|:
Human    25 LPQSLQSAFSGHSSFLVEDLIRISRPPAYLPRSVPTASMSPPRQGAPTALTDTGASDLGSPGPGS 89

  Fly   199 SNGVLYPNA--PYTDHGFLQMTLGYL-------SPSSGTYKSVD------PYFLSQASLFGGAPF 248
            ..|...|.|  |.::..||:..:..:       ..|....:||.      |||......|..:.:
Human    90 RRGGSPPTAFSPASETTFLKFGVNAILSSGPRTETSPALLQSVPPKTFAFPYFEGSFQPFIRSSY 154

  Fly   249 FGAPGCVPELALGLGMGVNALRHCRR-RKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALG 312
            |.|...|..:.......:.|....|| ...|.||||.|...|||.|:.|:|:|.|:|.:||..||
Human   155 FPASSSVVPIPGTFSWPLAARGKPRRGMLRRAVFSDVQRKALEKMFQKQKYISKPDRKKLAAKLG 219

  Fly   313 LSETQVKTWFQNRRMK----HKKQLRRRDNANEPV------------DFSRSEPGKQ-----PGE 356
            |.::|||.||||||||    .:::|.......|..            |..:..||.:     ||.
Human   220 LKDSQVKIWFQNRRMKWRNSKERELLSSGGCREQTLPTKLNPHPDLSDVGQKGPGNEEEEEGPGS 284

  Fly   357 -----ATSSSGDSKH-------GKLNPGSV-GGTPTQPTSEQQLQMCLMQQGYSTDDYSDLEADS 408
                 |..:|.|.:|       |.|.|... ..:|.:|:                 |:||.|.:.
Human   285 PSHRLAYHASSDPQHLRDPRLPGPLPPSPAHSSSPGKPS-----------------DFSDSEEEE 332

  Fly   409 GDED 412
            ..|:
Human   333 EGEE 336

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	31/59 (53%)
DBX1	NP_001025036.2	PRK12323	<49..182	CDD:481241	30/132 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	56..100		12/43 (28%)
		Homeodomain	184..238	CDD:459649	31/53 (58%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	240..343		21/114 (18%)