Protein Alignment bsh and LBX1

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_006553.2
• Gene: LBX1 / 10660
• HGNCID: 16960
• Length: 281
• Species: Homo sapiens
• Alignment Length: 280
• Identity: 83/280 - (29%)
• Similarity: 112/280 - (40%)
• Gaps: 73/280 - (26%)

  Fly   189 PPPLNGGSGASNGVLYP-------NAPYTDHGFLQMTLGYLSPSSGTYKSVDPYFLSQASLFGGA 246
            |||.|     ||..|.|       |.|.....:......:|..::..:..            ||.
Human    24 PPPAN-----SNKPLTPFSIEDILNKPSVRRSYSLCGAAHLLAAADKHAQ------------GGL 71

  Fly   247 PFFG-------APGC-VPELA----LGL------------GMGVNALRHC--RRRKARTVFSDPQ 285
            |..|       :|.| :.|||    .||            ||.:...|..  :|||:||.|::.|
Human    72 PLAGRALLSQTSPLCALEELASKTFKGLEVSVLQAAEGRDGMTIFGQRQTPKKRRKSRTAFTNHQ 136

  Fly   286 LSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRMKHKKQLR---------RRDNANE 341
            :..|||||..|:|||..:|.::|..|||:..||.|||||||.|.|:.|.         ::...:.
Human   137 IYELEKRFLYQKYLSPADRDQIAQQLGLTNAQVITWFQNRRAKLKRDLEEMKADVESAKKLGPSG 201

  Fly   342 PVDFSRSEPGKQPGEATSSSGDS-KHGKLNPGS---VGGTPTQPTSEQQLQMC----LMQQGYST 398
            .:|.......:|..|||:..|.. ...|..|||   ..|.|..| ....||:.    |..|..|:
Human   202 QMDIVALAELEQNSEATAGGGGGCGRAKSRPGSPVLPPGAPKAP-GAGALQLSPASPLTDQPASS 265

  Fly   399 DDYSDLEADSGDEDNSSDVD 418
            .|.|:     .:||...|||
Human   266 QDCSE-----DEEDEEIDVD 280

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	30/55 (55%)
LBX1	NP_006553.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..35		7/15 (47%)
		Homeodomain	126..182	CDD:459649	30/55 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	214..281		23/73 (32%)