Protein Alignment bsh and CDX4

DIOPT Version :10

• Sequence 1: NP_477350.2
• Gene: bsh / 35266
• FlyBaseID: FBgn0000529
• Length: 429
• Species: Drosophila melanogaster
• Sequence 2: NP_005184.1
• Gene: CDX4 / 1046
• HGNCID: 1808
• Length: 284
• Species: Homo sapiens
• Alignment Length: 317
• Identity: 82/317 - (25%)
• Similarity: 118/317 - (37%)
• Gaps: 85/317 - (26%)

  Fly   112 HPPASASASATATARSNQAASGYAGEDYGKSMHSTPRSNHHSRHGTSHYNGDQISQQLGSGAAQH 176
            :|....|.....||.:.....|      |..|   |.||..:....|||.|             :
Human    14 YPGTLMSPGGDGTAGTGGTGGG------GSPM---PASNFAAAPAFSHYMG-------------Y 56

  Fly   177 PPVPTTQPQ--------PPPPPPLNGGSGASNGVLYPNAPYTDHGFLQMTLGYLSPS---SGTYK 230
            |.:|:..|.        .|..||....|      :|| .|.:..|.:.:.....||:   |..|.
Human    57 PHMPSMDPHWPSLGVWGSPYSPPREDWS------VYP-GPSSTMGTVPVNDVTSSPAAFCSTDYS 114

  Fly   231 SVDPYFLSQASLFGGAPFFGAPG-----CVP-ELALGLGMGVNALRHC----------------R 273
            ::.|       :.||......||     .|| :.........:..||.                .
Human   115 NLGP-------VGGGTSGSSLPGQAGGSLVPTDAGAAKASSPSRSRHSPYAWMRKTVQVTGKTRT 172

  Fly   274 RRKARTVFSDPQLSGLEKRFEGQRYLSTPERVELATALGLSETQVKTWFQNRRMKHKKQLRRRDN 338
            :.|.|.|::|.|...|||.|...||::...:.|||..|||||.|||.||||||.|.:|.::::.:
Human   173 KEKYRVVYTDHQRLELEKEFHCNRYITIQRKSELAVNLGLSERQVKIWFQNRRAKERKMIKKKIS 237

  Fly   339 ANEPVDFSRSEPGKQPGEATSSSGDSKHGKLNPGSVGGT-PTQPTSEQQLQMCLMQQ 394
                 .|..|      |.:..|..||    ::||.:..| .|.|::.:..|...:||
Human   238 -----QFENS------GGSVQSDSDS----ISPGELPNTFFTTPSAVRGFQPIEIQQ 279

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
bsh	NP_477350.2	Homeodomain	275..331	CDD:459649	29/55 (53%)
CDX4	NP_005184.1	Caudal_act	13..170	CDD:461413	38/191 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	15..40		7/33 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	120..155		7/34 (21%)
		Homeodomain	175..230	CDD:459649	29/54 (54%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	238..259		8/30 (27%)