DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment fbp and Fbp1

DIOPT Version :9

Sequence 1:	NP_724223.4	Gene:	fbp / 35265	FlyBaseID:	FBgn0032820	Length:	343	Species:	Drosophila melanogaster
Sequence 2:	NP_036690.2	Gene:	Fbp1 / 24362	RGDID:	2595	Length:	363	Species:	Rattus norvegicus

Alignment Length:	331	Identity:	209/331 - (63%)
Similarity:	259/331 - (78%)	Gaps:	3/331 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 MTQQRPAFDSNAMTLTRFVLQEQRKFKSATGDLSQLLNSIQTAIKATSSAVRKAGIAKLHGFAGD 74
            |....| |:::..|||||||:|.|| ...||:::|||||:.|||||.|||||:||||:|:|.||.
  Rat     1 MVDHAP-FETDISTLTRFVLEEGRK-AGGTGEMTQLLNSLCTAIKAISSAVRQAGIAQLYGIAGS 63

  Fly    75 VNVQGEEVKKLDVLSNELFINMLKSSYTTCLMVSEENENVIEVEVEKQGKYIVCFDPLDGSSNID 139
            .||.|::|||||:|||:|.||||||||.||::||||:.:.|.:|.||:|||:|||||||||||||
  Rat    64 TNVTGDQVKKLDILSNDLVINMLKSSYATCVLVSEEDTHAIIIEPEKRGKYVVCFDPLDGSSNID 128

  Fly   140 CLVSIGSIFAIYRKKSDGPPTVEDALQPGNQLVAAGYALYGSATAIVLGLGSGVNGFTYDPAIGE 204
            ||.|||:||.||||.|...|:.:||||||..|||||||||||||.:||.:..|||.|..||:|||
  Rat   129 CLASIGTIFGIYRKTSANEPSEKDALQPGRNLVAAGYALYGSATMLVLAMNCGVNCFMLDPSIGE 193

  Fly   205 FVLTDPNMRVPEKGKIYSINEGYAADWEDGVFNYIAAKK-DPAKGKPYGARYVGSMVADVHRTIK 268
            |:|.|.::::.:||.|||||||||.|::..:..||..|| .|....|||||||||||||||||:.
  Rat   194 FILVDRDVKIKKKGNIYSINEGYAKDFDPAINEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLV 258

  Fly   269 YGGIFIYPATKSAPSGKLRLLYECVPMAYLMIQAGGLASDGKISILDIVPKKIHERSPIFLGSKS 333
            |||||:|||.|..|||||||||||.|:||:|.:|||||:.|...||||||.:||:::|:.:||..
  Rat   259 YGGIFLYPANKKNPSGKLRLLYECNPIAYVMEKAGGLATTGNEDILDIVPTEIHQKAPVIMGSTE 323

  Fly   334 DVEEAL 339
            ||:|.|
  Rat   324 DVQEFL 329

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fbp	NP_724223.4	FBPase	28..342	CDD:238214	201/313 (64%)
Fbp1	NP_036690.2	FBPase	18..332	CDD:238214	201/313 (64%)
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:P00636	122..125		2/2 (100%)
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:P00636	213..216		2/2 (100%)
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:P00636	244..249		4/4 (100%)
		Substrate binding. /evidence=ECO:0000250\|UniProtKB:P00636	275..277		1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166343142
Domainoid	1	1.000	253	1.000	Domainoid score	I1998
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	416	1.000	Inparanoid score	I1764
OMA	1	1.010	-	-		QHG61707
OrthoDB	1	1.010	-	-		D1381522at2759
OrthoFinder	1	1.000	-	-		FOG0001569
OrthoInspector	1	1.000	-	-		otm45711
orthoMCL	1	0.900	-	-		OOG6_101108
Panther	1	1.100	-	-	LDO	PTHR11556
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X880
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.910