Protein Alignment fbp and FBP1

DIOPT Version :10

• Sequence 1: NP_724223.4
• Gene: fbp / 35265
• FlyBaseID: FBgn0032820
• Length: 343
• Species: Drosophila melanogaster
• Sequence 2: NP_000498.2
• Gene: FBP1 / 2203
• HGNCID: 3606
• Length: 338
• Species: Homo sapiens
• Alignment Length: 335
• Identity: 214/335 - (63%)
• Similarity: 267/335 - (79%)
• Gaps: 6/335 - (1%)

  Fly    10 MTQQRPAFDSNAMTLTRFVLQEQRKFKSATGDLSQLLNSIQTAIKATSSAVRKAGIAKLHGFAGD 74
            |..|.| ||::..||||||::|.||.: .||:|:|||||:.||:||.||||||||||.|:|.||.
Human     1 MADQAP-FDTDVNTLTRFVMEEGRKAR-GTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGIAGS 63

  Fly    75 VNVQGEEVKKLDVLSNELFINMLKSSYTTCLMVSEENENVIEVEVEKQGKYIVCFDPLDGSSNID 139
            .||.|::|||||||||:|.:||||||:.||::||||:::.|.||.||:|||:|||||||||||||
Human    64 TNVTGDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDPLDGSSNID 128

  Fly   140 CLVSIGSIFAIYRKKSDGPPTVEDALQPGNQLVAAGYALYGSATAIVLGLGSGVNGFTYDPAIGE 204
            ||||:|:||.||||||...|:.:||||||..|||||||||||||.:||.:..|||.|..||||||
Human   129 CLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDCGVNCFMLDPAIGE 193

  Fly   205 FVLTDPNMRVPEKGKIYSINEGYAADWEDGVFNYIAAKK-DPAKGKPYGARYVGSMVADVHRTIK 268
            |:|.|.::::.:||||||:|||||.|::..|..||..|| .|....|||||||||||||||||:.
Human   194 FILVDKDVKIKKKGKIYSLNEGYARDFDPAVTEYIQRKKFPPDNSAPYGARYVGSMVADVHRTLV 258

  Fly   269 YGGIFIYPATKSAPSGKLRLLYECVPMAYLMIQAGGLASDGKISILDIVPKKIHERSPIFLGSKS 333
            |||||:|||.|.:|:|||||||||.||||:|.:|||:|:.||.::||::|..||:|:|:.|||..
Human   259 YGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGKEAVLDVIPTDIHQRAPVILGSPD 323

  Fly   334 DVEEALSYLK 343
            ||   |.:||
Human   324 DV---LEFLK 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fbp	NP_724223.4	FBPase	28..342	CDD:238214	202/314 (64%)
FBP1	NP_000498.2	FBPase	18..332	CDD:238214	204/317 (64%)