Protein Alignment CG10463 and DUS3

DIOPT Version :9

• Sequence 1: NP_610000.1
• Gene: CG10463 / 35264
• FlyBaseID: FBgn0032819
• Length: 604
• Species: Drosophila melanogaster
• Sequence 2: NP_013505.4
• Gene: DUS3 / 851117
• SGDID: S000004393
• Length: 668
• Species: Saccharomyces cerevisiae
• Alignment Length: 651
• Identity: 228/651 - (35%)
• Similarity: 360/651 - (55%)
• Gaps: 65/651 - (9%)

  Fly     4 GICYIKPEYLV--TEADGGSAAANTENSDTNKRKREDGGEVEAGEKKKWDKKERKRGQNKNRPVF 66
            ||.:|||||:|  .:.:....|...|...:::...|..|   ...||..:.:.:||||||||...
Yeast    28 GIAHIKPEYIVPLKQNENQKVAIYDEEMSSDRMTNEFAG---GTNKKNKNGRGKKRGQNKNRDNR 89

  Fly    67 KDERYSHLCHSLIDGTGGEPCSLA-NCRYVHDLDAYLAAK----GEDLGPECYVYTTKGYCARGV 126
            :.:..:.||..||.|...: ||.. |||:|||::.||:.|    ..::.|.|.|:.:.|:|..|.
Yeast    90 QVKEQNVLCPRLIHGDISK-CSFGDNCRFVHDINLYLSTKKPEVESNIFPSCPVFNSLGFCPMGF 153

  Fly   127 SCRFAKAHTDEQGRNL-KREDYDENAPPT-----TCNGVSSELQVRLRKHEYDFSRSKELIKM-- 183
            .|||..:|.:::...| .:::.|.:|...     ..|.:|.|.::.|.|..:.|::|.|::::
Yeast   154 KCRFLSSHLNKEDNILISKKEIDPDAQTIWSVKGEVNHISPERKLDLIKRRFPFTKSNEILEIID 218

  Fly   184 --AEKLRDARKLKEQQE-----KEKNPSEETG-----EKQPSETTEILDAEKQTDTKSKPTATGC 236
              .::.||:.|.:|:.|     |:::|..|..     |::..|.:|....:::...|.|.|.
Yeast   219 SFQQECRDSMKPEEEVESTPQLKKQDPDVEQPVAPQVEQRNKELSEHRMKQREVYLKYKDTR--- 280

  Fly   237 AIDDSAIGRDADHKPAVDFREKLVLSPLTTLGNLPFRRICKEFGADITCGEMACAQPLLKGMGQE 301
                    ..|..|..:|...|.::|||||:||||:||:.::.|||:|..|||.|.||::|...|
Yeast   281 --------YFAQEKKPLDLYHKKIVSPLTTVGNLPYRRLMRKLGADVTYSEMALAVPLIQGTNSE 337

  Fly   302 WALTKRHQSE-DVFGVQLCGNNPNMLNQAAQVI-HETAQVDFIDLNIGCPIDLIYQQGGGSALMR 364
            |||.|.|.|| ..||||:..:......:||:.: :..:::..|:||.||||||:|:||.||||:.
Yeast   338 WALPKAHTSEFPGFGVQVACSKAWQAAKAAEALANSVSEISEINLNSGCPIDLLYRQGSGSALLD 402

  Fly   365 RTNILELTVRSCAALSDRLPFTVKMRTGIYADKSVAHELLP-LVEEWGASAVTLHGRSREQRYTK 428
            ....:...:.:...:|..:|.|||:|||......:|..|:. ||.|...:|:|||||||:|||||
Yeast   403 NPARMIRCLNAMNYVSKDIPITVKIRTGTKEGHPIAEGLVKRLVNETDVAAITLHGRSRQQRYTK 467

  Fly   429 HANWAYIEECA-----AKAKCMPV---------------IGNGDILSYEDYMERRTLAPHVCSVM 473
            .|:|.|:.:.|     |:|..:..               :||||:.::||:........::.|||
Yeast   468 SADWDYVSQVADTLRSAEADFIETEQGKEGRDSKNRIQFVGNGDVNNFEDWYRYLNGNENIDSVM 532

  Fly   474 IGRGALIKPWIFQEIKEKQAWSPSSGQRYEMLQKFCNYGLEHWGSDTKGVETTRRFLLEWQSFLY 538
            :.||||||||||:|::.:|....:|.:|.::|:.:..:.:||||:|..|:...|||..|:.||.:
Yeast   533 VARGALIKPWIFEEVESQQYLDKTSTERLDILRDYAQFSMEHWGTDEYGISQCRRFFCEFMSFFH 597

  Fly   539 RYIPEALQTAPPQKINARPQKYRGRDEMETLMSSGNAADWVKLSESLLGRVPEGFTFVPKHKANA 603
            ||:|..:....|.|:|.||..:.||||:||||.|.:..||:|||:...|:..|.|.||||||:::
Yeast   598 RYVPMGICERYPVKLNERPPNWCGRDELETLMGSTDVNDWIKLSDLFFGKTDENFVFVPKHKSSS 662

  Fly   604 F 604
            :
Yeast   663 Y 663

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10463	NP_610000.1	DusA	253..547	CDD:223120	125/316 (40%)
		DUS_like_FMN	258..492	CDD:239200	105/256 (41%)
DUS3	NP_013505.4	zf-CCCH_4	96..120	CDD:407881	11/24 (46%)
		DusA	284..597	CDD:223120	123/312 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C157341600
Domainoid	1	1.000	153	1.000	Domainoid score	I913
eggNOG	1	0.900	-	-		E1_COG0042
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6533
Inparanoid	1	1.050	376	1.000	Inparanoid score	I348
Isobase	1	0.950	-	0	Normalized mean entropy	S1332
OMA	1	1.010	-	-		QHG55928
OrthoFinder	1	1.000	-	-		FOG0003900
OrthoInspector	1	1.000	-	-		oto99472
orthoMCL	1	0.900	-	-		OOG6_101202
Panther	1	1.100	-	-	LDO	PTHR45846
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R356
SonicParanoid	1	1.000	-	-		X2206
TreeFam	1	0.960	-	-
	16	15.740