DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10463 and CG3645

DIOPT Version :9

Sequence 1:	NP_610000.1	Gene:	CG10463 / 35264	FlyBaseID:	FBgn0032819	Length:	604	Species:	Drosophila melanogaster
Sequence 2:	NP_001259809.1	Gene:	CG3645 / 33190	FlyBaseID:	FBgn0031238	Length:	505	Species:	Drosophila melanogaster

Alignment Length:	392	Identity:	91/392 - (23%)
Similarity:	158/392 - (40%)	Gaps:	80/392 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   220 DAEKQTDTKSKPTATGCAIDDSAIGRDADHKPAVDFREKLVLSPLTTLGNLPFRRICKEFGADIT 284
            |.:......|||  ||.....|::|           ..:.|::|:.....|.:|.:|:.:||::
  Fly     4 DEDAAHQRPSKP--TGYNFYRSSLG-----------SPRYVVAPMVDQSELAWRMLCRRYGAEL- 54

  Fly   285 CGEMACAQPLLKGMGQEWALTKRHQSEDV--------FGVQLCGNNPNMLNQAAQVIHETAQVDF 341
                 |..|:..  ...:|...:::.:.:        ..:|.|||:...:..||.:..:  ..|.
  Fly    55 -----CYSPMYH--ANLFATDPKYRKDALQTCPEDRPLIIQFCGNDAQQILDAALLAQD--HCDA 110

  Fly   342 IDLNIGCPIDLIYQQGGGSALMRRTNIL-ELTVRSCAALSDRLPFTVKMRTGIYADKSVAHELLP 405
            :|:|:|||..:..:...||.|.....:| |:.....|.|:  :|.|.|:|  |:.|.........
  Fly   111 VDINLGCPQAIAKRGHYGSFLQDEWELLTEIVSTLHAKLA--VPVTCKIR--IFEDLEKTIRYAK 171

  Fly   406 LVEEWGASAVTLHGRSREQR--YTKHANWAYIEECAAKAKCMPVIGNGDILSYEDYMERRTLAPH 468
            ::|..|...:|:|||:|||:  .|..|||.||:......| :|::.||:||:.:| :.|......
  Fly   172 MLEAAGCQLLTVHGRTREQKGPLTGVANWNYIKNVRQHIK-IPMLANGNILALDD-VHRCLTETG 234

  Fly   469 VCSVMIGRGALIKPWIFQEIKEKQAWS--------------PSSGQRYEMLQKFCNYGLEHWGSD 519
            |..||...|.|..|.||:.: ....|.              |||..|..:.:.|.:.......|:
  Fly   235 VDGVMSAEGNLHNPAIFKGV-SPPVWQMAHEYLELVQLHPCPSSFIRGHLFKLFHHIMNIRQNSE 298

  Fly   520 TKGVETTRRFLLEWQSFLYR--------------YIPEALQTAPPQK-----------INARPQK 559
            .:....|...|:::|:.:.:              |.||.:.....:.           |.|.|:.
  Fly   299 LRQYLATANQLVQFQAVVQQVRAKYEPFHKGEVPYEPEQMAAGSEEDLPLSPWLCQPYIRASPES 363

  Fly   560 YR 561
            :|
  Fly   364 HR 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10463	NP_610000.1	DusA	253..547	CDD:223120	79/332 (24%)
CG10463	NP_610000.1	DUS_like_FMN	258..492	CDD:239200	66/244 (27%)
CG3645	NP_001259809.1	DUS_like_FMN	29..259	CDD:239200	66/246 (27%)
		Dus	31..303	CDD:279540	73/288 (25%)
		put_zinc_LRP1	426..>460	CDD:130684
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45464257
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0042
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.740