Protein Alignment CG10631 and ZNF212

DIOPT Version :9

• Sequence 1: NP_609998.1
• Gene: CG10631 / 35262
• FlyBaseID: FBgn0032817
• Length: 3781
• Species: Drosophila melanogaster
• Sequence 2: NP_036388.2
• Gene: ZNF212 / 7988
• HGNCID: 13004
• Length: 495
• Species: Homo sapiens
• Alignment Length: 328
• Identity: 64/328 - (19%)
• Similarity: 102/328 - (31%)
• Gaps: 110/328 - (33%)

  Fly   182 NIMTGSYPYIKS--------------EPMEAYQQPPNPMAPPPAPEVLIKSEPIDEHSYKSNYID 232
            |:|..:|..:.|              ..|....:...|....||..|:||.|        ..|..
Human   168 NVMESNYETLVSLKVLGQTEGEAELGTEMLGDLEEEGPGGAHPAGGVMIKQE--------LQYTQ 224

  Fly   233 DNTPFADF-SKFSEFSED--MLSPKVELTVKDESYGRTTSSFLRRKQQSDRGNESLPICQR---- 290
            :..  ||. .:||..:|:  .|||:     :.|.:|...||.|......|...|. |:..|
Human   225 EGP--ADLPGEFSCIAEEQAFLSPE-----QTELWGGQGSSVLLETGPGDSTLEE-PVGSRVPSS 281

  Fly   291 -----CKEVFFKKQVYLRHVAESNCG-------IQEYDFKCSTCPMSFMTTEELQRH-------- 335
                 |.:....:||.|    :..||       .....::||.|.::|...::|..|
Human   282 SRTVGCPKQKSHRQVQL----DQECGQGLKLKKDTSRPYECSECEITFRYKQQLATHLRSHSGWG 342

  Fly   336 ------------------------KLHHRAD----RFFC------HKYC--------GKHF---- 354
                                    || |:.|    .|.|      |:.|        |:|.
Human   343 SCTPEEPEESLRPRPRLKPQTKKAKL-HQCDVCLRSFSCKVSLVTHQRCHLQEGPSAGQHVQERF 406

  Fly   355 --DTIAECEAHEYMQHEYDSFVCNMCSGTFATREQLYAHLPQHKFQQRFDCPICRLWYQTALELH 417
              :::.....|...:....|.:|..|..:|:....|..|...|..::.:.|..|...:.....|.
Human   407 SPNSLVALPGHIPWRKSRSSLICGYCGKSFSHPSDLVRHQRIHTGERPYSCTECEKSFVQKQHLL 471

  Fly   418 EHR 420
            :|:
Human   472 QHQ 474

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10631	NP_609998.1	C2H2 Zn finger	288..311	CDD:275368	5/31 (16%)
		C2H2 Zn finger	319..339	CDD:275368	8/51 (16%)
		DM3	584..642	CDD:128933
		DM3	683..738	CDD:128933
		DM3	775..832	CDD:128933
		DM3	945..1000	CDD:128933
		DM3	1038..1096	CDD:128933
		DM3	1145..1198	CDD:128933
		THAP	1236..1308	CDD:214951
		DM3	1349..1406	CDD:128933
		THAP	1424..1493	CDD:214951
		DM3	1538..1596	CDD:128933
		DM3	1683..1739	CDD:128933
		DM3	1778..1831	CDD:128933
		DM3	1980..2033	CDD:128933
		DM3	2147..2202	CDD:128933
		DM3	2308..2365	CDD:128933
		DM3	2434..2491	CDD:128933
		DM3	2539..2598	CDD:128933
		DM3	2622..2680	CDD:128933
		DM3	2718..2775	CDD:128933
		DM3	2907..2965	CDD:128933
		DM3	3098..3155	CDD:128933
		DM3	3227..3284	CDD:128933
		DM3	3396..3452	CDD:128933
		DM3	3544..3601	CDD:128933
		THAP	3621..>3669	CDD:283206
		DM3	3690..3748	CDD:128933
ZNF212	NP_036388.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..29
		KRAB_A-box	142..180	CDD:143639	3/11 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	264..290		5/26 (19%)
		C2H2 Zn finger	318..338	CDD:275370	6/19 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	337..361		0/23 (0%)
		COG5048	<367..479	CDD:227381	22/109 (20%)
		C2H2 Zn finger	371..391	CDD:275368	4/19 (21%)
		C2H2 Zn finger	429..449	CDD:275368	5/19 (26%)
		zf-C2H2	429..449	CDD:306579	5/19 (26%)
		zf-H2C2_2	441..466	CDD:316026	5/24 (21%)
		C2H2 Zn finger	457..477	CDD:275368	4/18 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	476..495

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165156309
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24390
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.030