DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10631 and CTCF

DIOPT Version :9

Sequence 1:NP_609998.1 Gene:CG10631 / 35262 FlyBaseID:FBgn0032817 Length:3781 Species:Drosophila melanogaster
Sequence 2:NP_648109.1 Gene:CTCF / 38817 FlyBaseID:FBgn0035769 Length:818 Species:Drosophila melanogaster


Alignment Length:475 Identity:100/475 - (21%)
Similarity:159/475 - (33%) Gaps:127/475 - (26%)


- Green bases have known domain annotations that are detailed below.


  Fly   114 LNVSGAVVGGGGPNYGLGANTVAYAHNQLLQYQQQQQQQQQQQQQ----------------QQQQ 162
            |:.:||..||..|.....|:         |.:.::.:::::..:.                ::|:
  Fly    48 LDENGAEAGGSKPMEEAEAD---------LDHAEEAEEEEEDDEDKYFIDDEGNCYIKTTPKKQK 103

  Fly   163 HQHQHLPQHISQQRPYMGHNIMTGSYPYI-----KSEPMEAYQQPP------------------- 203
            ...:.|.|..::........:.|.:...|     ||.|.....:||                   
  Fly   104 ELQKKLKQAAAKPGKATRSVVSTATNKSINLRPAKSTPKATTSKPPPEPKAISVRPARAAAAKAK 168

  Fly   204 -NPMAPPPA-----------PE---VLIKSEPIDEHSYKSNYIDDNTPFADFSKFSEFSED---- 249
             :.|.||||           |.   |:.|.||:|........:|:....:..::.|:::.|    
  Fly   169 QSAMPPPPALVVKVPAPRGRPRKNPVIPKPEPMDLERELEELVDEPDISSMVTELSDYTVDEAAV 233

  Fly   250 -----MLSP-KVEL-------TVKDESYGRTTSSF-LRRKQ----------QSDRGNESLPICQR 290
                 .|:| :.|:       |.:||:..:....| |..|:          |:...:.....|..
  Fly   234 EAATATLTPNEAEVYEFEDNATTEDENADKKDVDFVLSNKEVKLKTASSTSQNSNASGHKYSCPH 298

  Fly   291 CKEVFFKKQVYLRHVAESNCGIQEYDFKCSTCPMSFMTTEELQRHKLHHRADRFFCHKYCGKHFD 355
            |.....||.:..||   |.....|..||||.|..||.:...||.|...|..::....|.|...|.
  Fly   299 CPYTASKKFLITRH---SRSHDVEPSFKCSICERSFRSNVGLQNHINTHMGNKPHKCKLCESAFT 360

  Fly   356 TIAECEAHEYMQHEYDS-FVCNMCSGTFATRE--QLYAHLPQHKFQQRFDCPICRLWYQTALELH 417
            |..|...|...:|..:. ..|..|  |:|:.|  :|..|:..|..::.:.||.|....|...:|.
  Fly   361 TSGELVRHTRYKHTKEKPHKCTEC--TYASVELTKLRRHMTCHTGERPYQCPHCTYASQDMFKLK 423

  Fly   418 EHRL----AAPY---FCGKYYTGGQSSSA-----SQSQAQQHQTNYKLQDC-----------HMA 459
            .|.:    ...|   .|...:|...|..|     |.......|.||....|           ||.
  Fly   424 RHMVIHTGEKKYQCDICKSRFTQSNSLKAHKLIHSVVDKPVFQCNYCPTTCGRKADLRVHIKHMH 488

  Fly   460 TMEMPTTPHHKTTPSGSSLP 479
            |.::|.|...    .|..||
  Fly   489 TSDVPMTCRR----CGQQLP 504

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10631NP_609998.1 C2H2 Zn finger 288..311 CDD:275368 7/22 (32%)
C2H2 Zn finger 319..339 CDD:275368 8/19 (42%)
DM3 584..642 CDD:128933
DM3 683..738 CDD:128933
DM3 775..832 CDD:128933
DM3 945..1000 CDD:128933
DM3 1038..1096 CDD:128933
DM3 1145..1198 CDD:128933
THAP 1236..1308 CDD:214951
DM3 1349..1406 CDD:128933
THAP 1424..1493 CDD:214951
DM3 1538..1596 CDD:128933
DM3 1683..1739 CDD:128933
DM3 1778..1831 CDD:128933
DM3 1980..2033 CDD:128933
DM3 2147..2202 CDD:128933
DM3 2308..2365 CDD:128933
DM3 2434..2491 CDD:128933
DM3 2539..2598 CDD:128933
DM3 2622..2680 CDD:128933
DM3 2718..2775 CDD:128933
DM3 2907..2965 CDD:128933
DM3 3098..3155 CDD:128933
DM3 3227..3284 CDD:128933
DM3 3396..3452 CDD:128933
DM3 3544..3601 CDD:128933
THAP 3621..>3669 CDD:283206
DM3 3690..3748 CDD:128933
CTCFNP_648109.1 23ISL <116..206 CDD:293226 18/89 (20%)
C2H2 Zn finger 296..316 CDD:275368 7/22 (32%)
COG5048 321..>621 CDD:227381 50/190 (26%)
zf-C2H2 322..344 CDD:278523 10/21 (48%)
C2H2 Zn finger 324..344 CDD:275368 8/19 (42%)
zf-H2C2_2 337..361 CDD:290200 7/23 (30%)
C2H2 Zn finger 352..373 CDD:275368 6/20 (30%)
C2H2 Zn finger 381..401 CDD:275368 7/21 (33%)
zf-H2C2_2 394..415 CDD:290200 6/20 (30%)
C2H2 Zn finger 409..429 CDD:275368 6/19 (32%)
zf-H2C2_2 422..446 CDD:290200 4/23 (17%)
C2H2 Zn finger 437..457 CDD:275368 4/19 (21%)
C2H2 Zn finger 467..485 CDD:275368 3/17 (18%)
C2H2 Zn finger 496..516 CDD:275370 3/13 (23%)
C2H2 Zn finger 524..544 CDD:275368
zf-H2C2_2 536..561 CDD:290200
C2H2 Zn finger 552..573 CDD:275368
zf-C2H2 587..609 CDD:278523
C2H2 Zn finger 589..609 CDD:275368
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR24390
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
11.100

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