DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10631 and ZNF710

DIOPT Version :9

Sequence 1:NP_609998.1 Gene:CG10631 / 35262 FlyBaseID:FBgn0032817 Length:3781 Species:Drosophila melanogaster
Sequence 2:XP_005254963.1 Gene:ZNF710 / 374655 HGNCID:25352 Length:679 Species:Homo sapiens


Alignment Length:555 Identity:114/555 - (20%)
Similarity:191/555 - (34%) Gaps:181/555 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   166 QHLPQ------HISQQRPYMGHNIMTG------SYPYIKSEPMEAYQQPPN--PMAPPPAPEVLI 216
            :|||:      :::...|:.......|      :.|..::.|.|...:||:  |::.|.||. :.
Human   172 RHLPRTPRPELNVAPYDPHFPAPARDGFPEPSMALPGPEALPTECGFEPPHLAPLSDPEAPS-ME 235

  Fly   217 KSEPIDEHSYKSNYIDDNTPFADFSKFSEFSEDMLSPKVELTVK------------DESYGRTTS 269
            ..||:..   :..::        :.:.|||..|.....||...|            |:||.....
Human   236 SPEPVKP---EQGFV--------WQEASEFEADTAGSTVERHKKAQLDRLDINVQIDDSYLVEAG 289

  Fly   270 SFLRRKQQSDRGNESLPICQRCKEVFFKKQVYLRHVAESNCGIQEYD------------------ 316
            ...:|.|           |:.|::.:..|...:.|:...| ||:.:.                  
Human   290 DRQKRWQ-----------CRMCEKSYTSKYNLVTHILGHN-GIKPHSCPHCSKLFKQPSHLQTHL 342

  Fly   317 --------FKCSTCPMSFMTTEELQRHK-LHHRADRFFCHKYCGKHFDTIAECEAHEYMQHEYDS 372
                    .||..|..:|..|..|:||. ||.....:.|| :||:.|...:|.:|||........
Human   343 LTHQGTRPHKCQVCHKAFTQTSHLKRHMLLHSEVKPYSCH-FCGRGFAYPSELKAHEVKHESGRC 406

  Fly   373 FVCNMCSGTFATREQLYAHLPQHKFQQRFDCPIC--RLWYQTALELH--EHRLAAPY-------- 425
            .||..|...|:|..||..||..|:....:.|..|  ...|::.|:.|  :|:...|:        
Human   407 HVCVECGLDFSTLTQLKRHLASHQGPTLYQCLECDKSFHYRSQLQNHMLKHQNVRPFVCTECGME 471

  Fly   426 -----------------------FCGKYYTGGQSSSASQSQAQQH---QTNYKLQDCHMA----- 459
                                   .||:.:|       .|:..::|   .|:.:...||:.     
Human   472 FSQIHHLKQHSLTHKGVKEFKCEVCGREFT-------LQANMKRHMLIHTSVRPYQCHICFKTFV 529

  Fly   460 ---TMEMPTTPHHKTTP-----SGSSLPATAALNSLLQQRQANADGAAMFAASAMKNEVNVKMER 516
               |::.....|....|     .|.|.   ..:.:||.....:| |:..|......::.|:|...
Human   530 QKQTLKTHMIVHSPVKPFKCKVCGKSF---NRMYNLLGHMHLHA-GSKPFKCPYCSSKFNLKGNL 590

  Fly   517 SYSNSTSESSYSVQDSGYNNAYG---------SDSSM-HAGA---IAG----PQAHSS------- 557
            |   ...:..:.|.|.|.::..|         :|::| |:||   :.|    .:|.:|       
Human   591 S---RHMKVKHGVMDIGLDSQGGWAKRNGQSRNDTNMTHSGASCPVRGVGRLAKAETSLGWAQVW 652

  Fly   558 ---TL---DDSEDALCCVPLCGVRKSTSPTLQFFT 586
               ||   ||:.|        |:..|:|..|...|
Human   653 KGGTLEGHDDNND--------GIFMSSSKDLNEIT 679

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10631NP_609998.1 C2H2 Zn finger 288..311 CDD:275368 5/22 (23%)
C2H2 Zn finger 319..339 CDD:275368 8/20 (40%)
DM3 584..642 CDD:128933 1/3 (33%)
DM3 683..738 CDD:128933
DM3 775..832 CDD:128933
DM3 945..1000 CDD:128933
DM3 1038..1096 CDD:128933
DM3 1145..1198 CDD:128933
THAP 1236..1308 CDD:214951
DM3 1349..1406 CDD:128933
THAP 1424..1493 CDD:214951
DM3 1538..1596 CDD:128933
DM3 1683..1739 CDD:128933
DM3 1778..1831 CDD:128933
DM3 1980..2033 CDD:128933
DM3 2147..2202 CDD:128933
DM3 2308..2365 CDD:128933
DM3 2434..2491 CDD:128933
DM3 2539..2598 CDD:128933
DM3 2622..2680 CDD:128933
DM3 2718..2775 CDD:128933
DM3 2907..2965 CDD:128933
DM3 3098..3155 CDD:128933
DM3 3227..3284 CDD:128933
DM3 3396..3452 CDD:128933
DM3 3544..3601 CDD:128933
THAP 3621..>3669 CDD:283206
DM3 3690..3748 CDD:128933
ZNF710XP_005254963.1 C2H2 Zn finger 297..317 CDD:275368 4/19 (21%)
C2H2 Zn finger 325..345 CDD:275368 0/19 (0%)
COG5048 <335..593 CDD:227381 57/272 (21%)
zf-H2C2_2 337..362 CDD:290200 4/24 (17%)
C2H2 Zn finger 353..373 CDD:275368 7/19 (37%)
zf-H2C2_2 365..390 CDD:290200 10/25 (40%)
C2H2 Zn finger 381..401 CDD:275368 9/20 (45%)
C2H2 Zn finger 409..429 CDD:275368 8/19 (42%)
zf-C2H2 435..457 CDD:278523 5/21 (24%)
C2H2 Zn finger 437..457 CDD:275368 5/19 (26%)
zf-H2C2_2 450..474 CDD:290200 4/23 (17%)
C2H2 Zn finger 465..485 CDD:275368 0/19 (0%)
C2H2 Zn finger 493..513 CDD:275368 5/26 (19%)
zf-H2C2_2 505..530 CDD:290200 4/24 (17%)
C2H2 Zn finger 521..541 CDD:275368 3/19 (16%)
zf-H2C2_2 534..558 CDD:290200 4/26 (15%)
C2H2 Zn finger 549..569 CDD:275368 4/22 (18%)
C2H2 Zn finger 577..596 CDD:275368 3/21 (14%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165156318
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.930

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