Protein Alignment CG10631 and LOC3290002

DIOPT Version :10

• Sequence 1: NP_609998.1
• Gene: CG10631 / 35262
• FlyBaseID: FBgn0032817
• Length: 3781
• Species: Drosophila melanogaster
• Sequence 2: XP_556220.4
• Gene: LOC3290002 / 3290002
• VectorBaseID: AGAMI1_014257
• Length: 580
• Species: Anopheles gambiae
• Alignment Length: 693
• Identity: 124/693 - (17%)
• Similarity: 230/693 - (33%)
• Gaps: 244/693 - (35%)

  Fly   928 CCVPS-CESKRHN----NENITFHTIPRRP---EQMRKWCHNLKIPEEKM-HKGMRICSLHF--E 981
            ||..| |::.|:|    ..:|||||.|  |   ..:|:|....:..|:.: :|...:||.||  :
Mosquito     5 CCSASFCKNNRYNVNRRGLDITFHTFP--PLNYHNVRQWIEFCQREEDWLPNKHSVLCSAHFRDD 67

  Fly   982 PYCIGGC-----------MRPFAVPTLNLGHDDDDIHRNPDVIKKLNIRETCCVAVCKRNRDRDH 1035
            .:.:..|           ::.:|||::        :.|.|..:.|....:...:.:.....::|.
Mosquito    68 DFQMNNCPIIKQGKRLRHLKGYAVPSV--------MSRPPITLSKRQKLDEVRIKLLANLYNKDE 124

  Fly  1036 ANL-----HRFPSNVSLLTKWCGNLQRPVPDGSKLFNDAICEVHFEER-------CLRNKRLEKW 1088
            .|.     |.:           ...:...|:.....|.....::|.:|       |||....:..
Mosquito   125 HNTGSENDHTY-----------SEAKTDEPEQRDPLNGCKKSIYFLQRYPNVCAFCLRLMEDDSV 178

  Fly  1089 AVPTLSLGHENIPYPLPTPEQVTEFYSRPTAPNNGEEQGE---------C--CVETCKRNPSVDD 1142
            .:|   |||.:........:::.|....|.   :.|::.:         |  |:||.
Mosquito   179 FLP---LGHFHDSLECTIEQKLDEITGDPM---DQEDRSDVQNLLPDKVCEECLETL-------- 229

  Fly  1143 IKLYRPPEEASVLAKWAHNLQTESSQLTSMRICNLHFEAHCIGKRMRPWAIPTLNLAGTIENLYE 1207
            ||.::...:...:.|::.::                  ||.:.....|           :||||:
Mosquito   230 IKFHQYQRQLDCMKKFSTSI------------------AHLLHGNPNP-----------LENLYQ 265

  Fly  1208 NPEHSMLYKRRTHMKAKQSASVKPTWVPRCCLPHCRKVRALHNVQLYRFPKLNRS---------T 1263
            :..                             |:.  |..|.|:.:.:..::|:|         :
Mosquito   266 DQG-----------------------------PYL--VNILRNLDIAQGKRINQSLEQVLEEVTS 299

  Fly  1264 LAKWAHNLQVPMVGSAQ-RRLCSAHFEPHVLSKKCPVPLAVPTLDLNAPPGLKIYQNPAKLKASK 1327
            ..:...||.:...|.|. |....:......||:...:      .|.:...|..:|::|...::.:
Mosquito   300 YGQDKQNLPIYAEGPADPRSFDQSSSTDDALSESMDI------CDESGATGPAVYKSPGTARSGE 358

  Fly  1328 LCLQRVCIVE----SCRKTRAQGVQLFRL---PHSPTQLRKW-------MHNIKTRPRA------ 1372
            ..|:   |.|    :.||..|:..:..:|   |:| |..:||       ..:||...::
Mosquito   359 RTLE---IYEVPHGNSRKRLAEKNETQKLHTCPYS-TICQKWFLTEEAVQQHIKEEHKSFDCHIC 419

  Fly  1373 -AMRAQYRVCSRHFETH--------SFNGRRLSAGAI------------------PT-------- 1402
             :..|.|.:..:|.|:|        |.|..|..:.:|                  ||
Mosquito   420 GSKIAFYDLYQKHMESHTIARALLRSHNRTRALSESISSVIRDESSQLEQKKRPKPTGNYVCGTC 484

  Fly  1403 LELGHDDEDIYPNEAQAFADEHCVVEGCEASKEQPDVRLFRFPTEDDDMLWKWCNNLKMNPVDCT 1467
            |.:..||:|        |:...|.:    ||..       :..|..|.:|.|...|..:.|....
Mosquito   485 LGVFVDDQD--------FSSHRCSL----ASST-------KLATPQDILLSKRNRNFTITPEHAL 530

  Fly  1468 GVRICNKHFEADCIGPKHLYKWAIPTEELGHDDA----DIELV 1506
            .....:|     ||..|..:. .:.|....:|::    |||::
Mosquito   531 SATAGSK-----CIASKTFFP-PVGTANHSNDNSVKLLDIEIL 567

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10631	NP_609998.1	C2H2 Zn finger	288..311	CDD:275368
		C2H2 Zn finger	319..339	CDD:275368
		DM3	584..642	CDD:128933
		DM3	683..738	CDD:128933
		DM3	775..832	CDD:128933
		DM3	945..1000	CDD:128933	17/71 (24%)
		DM3	1038..1096	CDD:128933	9/69 (13%)
		DM3	1145..1198	CDD:128933	4/52 (8%)
		THAP	1236..1308	CDD:214951	13/81 (16%)
		DM3	1349..1406	CDD:128933	20/107 (19%)
		THAP	1424..1493	CDD:214951	13/68 (19%)
		DM3	1538..1596	CDD:128933
		DM3	1683..1739	CDD:128933
		DM3	1778..1831	CDD:128933
		DM3	1980..2033	CDD:128933
		DM3	2147..2202	CDD:128933
		DM3	2308..2365	CDD:128933
		DM3	2434..2491	CDD:128933
		DM3	2539..2598	CDD:128933
		DM3	2622..2680	CDD:128933
		DM3	2718..2775	CDD:128933
		DM3	2907..2965	CDD:128933
		DM3	3098..3155	CDD:128933
		DM3	3227..3284	CDD:128933
		DM3	3396..3452	CDD:128933
		DM3	3544..3601	CDD:128933
		THAP	3622..>3673	CDD:461662
		DM3	3690..3748	CDD:128933
LOC3290002	XP_556220.4	None