DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10631 and Zfp667

DIOPT Version :9

Sequence 1:NP_609998.1 Gene:CG10631 / 35262 FlyBaseID:FBgn0032817 Length:3781 Species:Drosophila melanogaster
Sequence 2:NP_001008557.1 Gene:Zfp667 / 308326 RGDID:1359114 Length:608 Species:Rattus norvegicus


Alignment Length:320 Identity:75/320 - (23%)
Similarity:121/320 - (37%) Gaps:69/320 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   262 ESYGRTTSSFLRRKQQSDRGNESLPI-CQRCKEVFFKKQVYLRHVAESNCGIQEYDFKCSTCP-- 323
            :|:.|.::..|.::..:. ||   |. |.:|::.|.:....:.|: ..:.|  |..|||:.|.  
  Rat   335 KSFSRISALMLHQRAHTS-GN---PYKCDKCQKDFGRLSTLILHL-RIHSG--EKQFKCNKCEKV 392

  Fly   324 ----MSFMTTEELQRHKLHHRADRFFCHKYCGKHFDTIAECEAHEYMQHEYDSFVCNMCSGTFAT 384
                .||     :|..|:|.|..:....|.|||.|..:...:.|..:..|...|.||.||..|..
  Rat   393 CNRLSSF-----IQHKKIHKRKKKLIECKECGKMFGGMKNLKVHLNIHSEEKPFKCNKCSKVFGR 452

  Fly   385 REQLYAHLPQHKFQQRFDCPICRLWYQTALELHEHRLA----APY---FCGKYYTGGQSSSASQS 442
            :..|..|...|..::.:.|..|...:...:.|..|:..    .||   .|||.:    |.||..:
  Rat   453 QSFLSEHQRIHTGEKPYQCEECGKAFSHRISLTRHKRIHSEDRPYECDLCGKAF----SQSAHLA 513

  Fly   443 QAQQHQTNYKLQDCHMATMEMPTTPHHKTTPSGSSLPATAALNSLLQQR--------QANADGAA 499
            |.::..|..|...|.:.....                 |..::.:|.:|        :.|..|.|
  Rat   514 QHERIHTGEKPYACKICKKSF-----------------TQRISLILHERSHTGEKPYECNECGKA 561

  Fly   500 MFAASAMKNEVNVKMERSYSNSTSESSYSVQDSGYNNAYGSDSSMHAGAIAGPQAHSSTL 559
            ..:.|.:     ::.:||:|   ||..|.....|  .||...||:    |.....||..:
  Rat   562 FSSGSDL-----IRHQRSHS---SEKPYECSKCG--KAYSRSSSL----IRHQSIHSEEM 607

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10631NP_609998.1 C2H2 Zn finger 288..311 CDD:275368 4/22 (18%)
C2H2 Zn finger 319..339 CDD:275368 6/25 (24%)
DM3 584..642 CDD:128933
DM3 683..738 CDD:128933
DM3 775..832 CDD:128933
DM3 945..1000 CDD:128933
DM3 1038..1096 CDD:128933
DM3 1145..1198 CDD:128933
THAP 1236..1308 CDD:214951
DM3 1349..1406 CDD:128933
THAP 1424..1493 CDD:214951
DM3 1538..1596 CDD:128933
DM3 1683..1739 CDD:128933
DM3 1778..1831 CDD:128933
DM3 1980..2033 CDD:128933
DM3 2147..2202 CDD:128933
DM3 2308..2365 CDD:128933
DM3 2434..2491 CDD:128933
DM3 2539..2598 CDD:128933
DM3 2622..2680 CDD:128933
DM3 2718..2775 CDD:128933
DM3 2907..2965 CDD:128933
DM3 3098..3155 CDD:128933
DM3 3227..3284 CDD:128933
DM3 3396..3452 CDD:128933
DM3 3544..3601 CDD:128933
THAP 3621..>3669 CDD:283206
DM3 3690..3748 CDD:128933
Zfp667NP_001008557.1 KRAB 14..74 CDD:214630
KRAB 14..53 CDD:279668
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 75..143
COG5048 141..599 CDD:227381 73/310 (24%)
C2H2 Zn finger 146..166 CDD:275368
C2H2 Zn finger 174..194 CDD:275368
C2H2 Zn finger 202..222 CDD:275368
C2H2 Zn finger 255..275 CDD:275368
C2H2 Zn finger 283..301 CDD:275368
C2H2 Zn finger 330..350 CDD:275368 3/14 (21%)
C2H2 Zn finger 358..378 CDD:275368 4/20 (20%)
C2H2 Zn finger 415..435 CDD:275368 6/19 (32%)
zf-H2C2_2 427..452 CDD:290200 8/24 (33%)
C2H2 Zn finger 443..463 CDD:275368 7/19 (37%)
zf-H2C2_2 456..480 CDD:290200 5/23 (22%)
C2H2 Zn finger 471..491 CDD:275368 4/19 (21%)
zf-H2C2_2 483..508 CDD:290200 7/28 (25%)
C2H2 Zn finger 499..519 CDD:275368 7/23 (30%)
zf-H2C2_2 511..536 CDD:290200 4/41 (10%)
C2H2 Zn finger 527..547 CDD:275368 4/36 (11%)
zf-H2C2_2 539..564 CDD:290200 5/24 (21%)
C2H2 Zn finger 555..575 CDD:275368 5/24 (21%)
zf-H2C2_2 567..592 CDD:290200 9/34 (26%)
C2H2 Zn finger 583..603 CDD:275368 6/25 (24%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C166350250
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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