DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10631 and Zfp366

DIOPT Version :9

Sequence 1:NP_609998.1 Gene:CG10631 / 35262 FlyBaseID:FBgn0032817 Length:3781 Species:Drosophila melanogaster
Sequence 2:NP_001004149.1 Gene:Zfp366 / 238803 MGIID:2178429 Length:746 Species:Mus musculus


Alignment Length:692 Identity:127/692 - (18%)
Similarity:214/692 - (30%) Gaps:223/692 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly    57 VASYP---TPHSAFGPAPA--PSCKAANNSGSGNNNNNIMGGGGYGPGGGGAQGYYGAAGGGLNV 116
            :.|:|   .|.::.|.||.  |..:|..                    |..:|..|..:.|.|:.
Mouse    22 IPSFPHCLQPEASRGKAPQRHPFPEALR--------------------GPFSQFRYEPSPGDLDG 66

  Fly   117 SGAVVGGGGPNYGLGANT-VAYAH-----------------NQLLQYQQQQQQQQQQQQQQ---- 159
            ...|..|||........| |.|.|                 |..|.:.|.|:.:...|...    
Mouse    67 FPEVFEGGGSRKRKSMPTKVPYTHPAEEASIAQESKSLGPPNLTLLFPQPQRPKCDSQMIDLCNV 131

  Fly   160 --QQQHQHQHLPQHISQQRPYMGHNIMTGSYPYIKSEPMEAYQQPPNPMAPPPAPEVLIKSEPID 222
              |.....:||                 |..| :|.||::     |:.|.|.|.|...:.:    
Mouse   132 GLQFYRTLEHL-----------------GGKP-VKQEPVK-----PSAMWPQPTPPAFLPA---- 169

  Fly   223 EHSYKSN---------YIDDNTPFADFSKFS----EFSEDMLSPKVELTVKDESYGRTTSSFLRR 274
            .:.|...         ::..::|| .||:.:    :..|.:|..|||....:|:           
Mouse   170 PYPYYPKVHPGLMFPFFVPSSSPF-PFSRHTFLPKQPPEPVLPRKVEPLESEET----------- 222

  Fly   275 KQQSDRGNESLPI----------------CQRCKEVFFKKQVYLRHV---------AESNCG--- 311
            ||:.:|.:.::.|                |..|::.:..|...:.|:         |.|.||   
Mouse   223 KQKVERVDVNVQIDDSYYVDVGGAQKRWQCPTCEKSYTSKYNLVTHILGHSGIKPHACSRCGKLF 287

  Fly   312 -----IQEY--------DFKCSTCPMSFMTTEELQRHKLHHRADRFFCHKYCGKHFDTIAECEAH 363
                 :..:        ..||..|..:|..|..|:||.:.|...:....:.|.:.|...:|.:||
Mouse   288 KQLSHLHTHMLTHQGTRPHKCQVCHKAFTQTSHLKRHMMQHSEVKPHNCRVCSRGFAYPSELKAH 352

  Fly   364 EYMQHEYDSFVCNMCSGTFATREQLYAHLPQHKFQQRFDCPICRLWYQTALELHEHRL----AAP 424
            |.........:|..|...|.|..||..||..|:...:::|..|...:|...:|..|.:    ..|
Mouse   353 EAKHASGRENICVECGLDFPTLAQLKRHLTTHRGPIQYNCSECDKTFQYPSQLQNHMMKHKDIRP 417

  Fly   425 YFCGK--------YYTGGQSSSASQSQAQQHQ---------------------TNYKLQDCHMA- 459
            |.|.:        ::.  :..|.:....::|:                     ||.:...||:. 
Mouse   418 YICSECGMEFVQPHHL--KQHSLTHKGVKEHKCGICGREFTLLANMKRHVLIHTNIRAYQCHLCY 480

  Fly   460 -------TMEMPTTPHHKTTPSGSSLPATA--ALNSLLQQRQANADG---AAMFAASAMKNEVNV 512
                   |::.....|....|....|....  .:::|:.....::|.   ..::..|....:.|:
Mouse   481 KSFVQKQTLKAHMIVHSDVKPFKCKLCGKEFNRMHNLMGHLHLHSDSKPFKCLYCPSKFTLKGNL 545

  Fly   513 KMERSYSNSTSESSYSVQDSGYNNAYGSDSSMHAGAIA-----------------GPQAHSSTLD 560
            .......:...|.....|..|........|   ||.:.                 ||. ..|.:|
Mouse   546 TRHMKVKHGVMERGLHSQGLGRGRLVLVQS---AGVLRNLEQEEPFDLSQKRSANGPM-FQSDVD 606

  Fly   561 DSEDALC------------CVPLCGVRKSTSPTLQFFTFPKD 590
            .::|.||            |..:.....|.:|..|....|:|
Mouse   607 STQDCLCQEEEEEAGEEDNCYEVEPYSPSLAPESQQLCAPED 648

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10631NP_609998.1 C2H2 Zn finger 288..311 CDD:275368 6/31 (19%)
C2H2 Zn finger 319..339 CDD:275368 7/19 (37%)
DM3 584..642 CDD:128933 2/7 (29%)
DM3 683..738 CDD:128933
DM3 775..832 CDD:128933
DM3 945..1000 CDD:128933
DM3 1038..1096 CDD:128933
DM3 1145..1198 CDD:128933
THAP 1236..1308 CDD:214951
DM3 1349..1406 CDD:128933
THAP 1424..1493 CDD:214951
DM3 1538..1596 CDD:128933
DM3 1683..1739 CDD:128933
DM3 1778..1831 CDD:128933
DM3 1980..2033 CDD:128933
DM3 2147..2202 CDD:128933
DM3 2308..2365 CDD:128933
DM3 2434..2491 CDD:128933
DM3 2539..2598 CDD:128933
DM3 2622..2680 CDD:128933
DM3 2718..2775 CDD:128933
DM3 2907..2965 CDD:128933
DM3 3098..3155 CDD:128933
DM3 3227..3284 CDD:128933
DM3 3396..3452 CDD:128933
DM3 3544..3601 CDD:128933
THAP 3621..>3669 CDD:283206
DM3 3690..3748 CDD:128933
Zfp366NP_001004149.1 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..64 12/61 (20%)
FtsK <51..>227 CDD:332908 43/214 (20%)
COG5048 250..>546 CDD:227381 54/297 (18%)
C2H2 Zn finger 252..272 CDD:275368 4/19 (21%)
C2H2 Zn finger 280..300 CDD:275368 3/19 (16%)
C2H2 Zn finger 308..328 CDD:275368 7/19 (37%)
C2H2 Zn finger 336..356 CDD:275368 6/19 (32%)
C2H2 Zn finger 364..384 CDD:275368 8/19 (42%)
C2H2 Zn finger 392..412 CDD:275368 5/19 (26%)
C2H2 Zn finger 420..440 CDD:275368 2/21 (10%)
C2H2 Zn finger 448..468 CDD:275368 0/19 (0%)
Interaction with NRIP1. /evidence=ECO:0000250|UniProtKB:Q8N895 452..746 31/201 (15%)
C2H2 Zn finger 476..496 CDD:275368 3/19 (16%)
C2H2 Zn finger 504..524 CDD:275368 2/19 (11%)
C2H2 Zn finger 532..551 CDD:275368 2/18 (11%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 587..689 13/63 (21%)
PXDLS. /evidence=ECO:0000250|UniProtKB:Q8N895 587..591 0/3 (0%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167846716
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.930

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