DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG10631 and Zfp212

DIOPT Version :9

Sequence 1:NP_609998.1 Gene:CG10631 / 35262 FlyBaseID:FBgn0032817 Length:3781 Species:Drosophila melanogaster
Sequence 2:NP_663551.2 Gene:Zfp212 / 232784 MGIID:2682609 Length:492 Species:Mus musculus


Alignment Length:273 Identity:53/273 - (19%)
Similarity:86/273 - (31%) Gaps:79/273 - (28%)


- Green bases have known domain annotations that are detailed below.


  Fly   210 PAPEVLIKSEPIDEHSYKSNYIDDNTPFADFSKFSEFSEDMLSPKVELTVKDESYGRTTSSFLRR 274
            |....|::|.|.|.                            :|:...|.:|.:.||...  ..|
Mouse   252 PGDSALLESGPGDS----------------------------NPESVETSRDPAPGRNLD--CPR 286

  Fly   275 KQQSDR----GNE----------SLPI-CQRCKEVFFKKQVYLRHVAESNCGIQEYD-------- 316
            ||:|.|    |.|          |.|. |..|:..|..||....|: :|:.|.:.|.        
Mouse   287 KQKSHRQVQLGQECGQGLKVKRDSSPYKCPECQISFRYKQQLTAHL-QSHAGRESYSATEPEESL 350

  Fly   317 ---------------FKCSTCPMSFMTTEELQRHKLHHRADRFFCHKYCGKHF--DTIAECEAHE 364
                           .:|..|..||.....|..|:..|:.:.........:.|  :::.....|.
Mouse   351 RPRPRLKPQAKRSKLHQCDVCHRSFSCKVSLVTHQRCHQQEGPSTSPQIQERFSPNSLVALPGHI 415

  Fly   365 YMQHEYDSFVCNMCSGTFATREQLYAHLPQHKFQQRFDCPICRLWYQTALELHEHRLAAPYFCGK 429
            ..:....|.:|..|..:|:....|..|...|..::.:.||.|...:.....|.:|:        |
Mouse   416 PWRKSRSSLICGYCGKSFSHPSDLVRHQRIHTGERPYSCPECEKSFVQKQHLLQHQ--------K 472

  Fly   430 YYTGGQSSSASQS 442
            .:...:...||:|
Mouse   473 IHQRERGGLASES 485

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10631NP_609998.1 C2H2 Zn finger 288..311 CDD:275368 7/22 (32%)
C2H2 Zn finger 319..339 CDD:275368 6/19 (32%)
DM3 584..642 CDD:128933
DM3 683..738 CDD:128933
DM3 775..832 CDD:128933
DM3 945..1000 CDD:128933
DM3 1038..1096 CDD:128933
DM3 1145..1198 CDD:128933
THAP 1236..1308 CDD:214951
DM3 1349..1406 CDD:128933
THAP 1424..1493 CDD:214951
DM3 1538..1596 CDD:128933
DM3 1683..1739 CDD:128933
DM3 1778..1831 CDD:128933
DM3 1980..2033 CDD:128933
DM3 2147..2202 CDD:128933
DM3 2308..2365 CDD:128933
DM3 2434..2491 CDD:128933
DM3 2539..2598 CDD:128933
DM3 2622..2680 CDD:128933
DM3 2718..2775 CDD:128933
DM3 2907..2965 CDD:128933
DM3 3098..3155 CDD:128933
DM3 3227..3284 CDD:128933
DM3 3396..3452 CDD:128933
DM3 3544..3601 CDD:128933
THAP 3621..>3669 CDD:283206
DM3 3690..3748 CDD:128933
Zfp212NP_663551.2 KRAB_A-box 142..180 CDD:143639
zf-C2H2 313..335 CDD:278523 6/22 (27%)
C2H2 Zn finger 315..335 CDD:275368 6/20 (30%)
COG5048 <358..>474 CDD:227381 22/123 (18%)
C2H2 Zn finger 368..388 CDD:275368 6/19 (32%)
C2H2 Zn finger 426..446 CDD:275368 5/19 (26%)
zf-C2H2 426..446 CDD:278523 5/19 (26%)
zf-H2C2_2 438..463 CDD:290200 6/24 (25%)
C2H2 Zn finger 454..474 CDD:275368 6/27 (22%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167846712
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24390
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
22.030

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