Protein Alignment CG10631 and thap7

DIOPT Version :10

• Sequence 1: NP_609998.1
• Gene: CG10631 / 35262
• FlyBaseID: FBgn0032817
• Length: 3781
• Species: Drosophila melanogaster
• Sequence 2: NP_001429232.1
• Gene: thap7 / 100006965
• ZFINID: ZDB-GENE-040914-84
• Length: 639
• Species: Danio rerio
• Alignment Length: 671
• Identity: 134/671 - (19%)
• Similarity: 235/671 - (35%)
• Gaps: 174/671 - (25%)

  Fly  1760 CALSHCRKRRSID---NDLRTYRYP-RSEDLLEKWRANLRLAPDQCRGR---------ICADHFE 1811
            |:...|:.|.:.|   :.:..:|.| :.......|..|.|....:.:|:         .|:.||.
Zfish    17 CSAVGCKSRDTKDVRKSGITFHRLPKKGNPRRTTWIINSRRKGPEGKGQWDPQSGFIYFCSKHFT 81

  Fly  1812 ------SQVRGKLKLKTGAVPTLNLGHDEGLIYDNEAIKVGMTEEEEGS----SEMTRLKPKREL 1866
                  |.|.|..:||..|:||         :::.|..|.|...:..|.    .:.|.:|...:
Zfish    82 PDSFELSGVSGYHRLKDDAIPT---------VFEIEPHKKGTAGKRRGRPRNVDKCTSIKNSTK- 136

  Fly  1867 IDEEEEELEAEEEPHEHDMYDEDEK-DGHYFDPLELVETFAEHPSDDEAEYRGDEEDERDEDEDL 1930
             ||..|..|........|..:|.|| :.|...|       ...||.| |....||....|:..|
Zfish   137 -DEAFESPEIFTNATVADTDNECEKGEDHQSQP-------PPQPSSD-APQNSDETTLEDQTPD- 191

  Fly  1931 DEAEHFHPDNPPTPPTIPLRREKPANNVTPICCLR--------HCRKERT--------------- 1972
                      ||:||..|    :|.   :|.|.::        :..||.:
Zfish   192 ----------PPSPPPSP----RPP---SPSCYMKRLPPPPGFYLPKEHSYAQLCPLVWRKRYDK 239

  Fly  1973 -------AFHLLSTFGFPKD--RQLLLKWCAN-----LHLNPDDCIGRVCIEHFQPEVLGTR--- 2020
                   |..|||.....::  |..||:...|     |....|...|:        ||.|.|
Zfish   240 AIDSLEKALRLLSAARRRENRLRNALLRLRENRLKSTLLRARDGAKGK--------EVKGGRFSS 296

  Fly  2021 --KLKQNAVPTLNVGHDEPLRYSCNGMDLDQEQLQPQHSVFRLWSLKHCRKRKLTEPP------- 2076
              ..|...|......:.|.|....|....|:..|     :...|:.:...|.|:|...
Zfish   297 WASQKGQGVKVDRGCNLEGLEEGTNEGTTDEIDL-----IAEGWNGQTQTKGKVTAEEEEGCCFY 356

  Fly  2077 ---DIRQNKWS----AEV--RKMQRLRMEMKMKIGREIKLEVQTEREMKSK-EKTPTTSLGKIKL 2131
               |...||.|    |.|  .::|..:::.|.|..:|:|.:.:..:|.|.: .:|..:.:.:...
Zfish   357 CGRDNEGNKVSGYKEAPVGPEEVQGSQVKQKPKRIQEVKTKAKVIKEQKPEISRTDVSPVEQQSY 421

  Fly  2132 EICCINSCANDDVNQLLQLP-EDQNLLRKWQHNLKLSVDTDFKEIQVCLKHFEEQV------VQN 2189
            .:....:..|:|..|::.:. :...|..:.:.:|:|:...:..: ||.|.|....:      ||.
Zfish   422 YLYYCENAENEDAMQVVTMELQPHQLSTEDEASLELNSTAEAIQ-QVALLHPNTDLHTAPGPVQY 485

  Fly  2190 GKPLEQAVPTLQLDQNSWNIYRNSGNCLFPECSNSSSDQLSFVDLPGNAVIRDAWMSHLNLPPSS 2254
            ...|::.....||.|  ..:.:.......|:.:...:.::. |:......::|....|:.|
Zfish   486 SATLQETSAPFQLQQ--IQLLQPHQGLFLPDLAAKENSEME-VEQQHLYWVQDRSDEHVLL---- 543

  Fly  2255 EGLLCSEHFMQLFEQVEYPKVLAAQDLEDLQWIVDEL--RCAVPSCSSKSDGDLQLIPFPKKDAT 2317
                     ||:.|:.|..:|       |::.:::.|  :..:....:||..:..::.. |.|:|
Zfish   544 ---------MQVPERTERNQV-------DVETVIETLQPQAILERFQTKSTEERDVLTV-KCDST 591

  Fly  2318 LLKWLQNTKISYD--HLKHKS 2336
            .|     |...::  ||.|:|
Zfish   592 AL-----TSAGWENGHLSHQS 607

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10631	NP_609998.1	C2H2 Zn finger	288..311	CDD:275368
		C2H2 Zn finger	319..339	CDD:275368
		DM3	584..642	CDD:128933
		DM3	683..738	CDD:128933
		DM3	775..832	CDD:128933
		DM3	945..1000	CDD:128933
		DM3	1038..1096	CDD:128933
		DM3	1145..1198	CDD:128933
		THAP	1236..1308	CDD:214951
		DM3	1349..1406	CDD:128933
		THAP	1424..1493	CDD:214951
		DM3	1538..1596	CDD:128933
		DM3	1683..1739	CDD:128933
		DM3	1778..1831	CDD:128933	17/68 (25%)
		DM3	1980..2033	CDD:128933	13/64 (20%)
		DM3	2147..2202	CDD:128933	10/61 (16%)
		DM3	2308..2365	CDD:128933	9/31 (29%)
		DM3	2434..2491	CDD:128933
		DM3	2539..2598	CDD:128933
		DM3	2622..2680	CDD:128933
		DM3	2718..2775	CDD:128933
		DM3	2907..2965	CDD:128933
		DM3	3098..3155	CDD:128933
		DM3	3227..3284	CDD:128933
		DM3	3396..3452	CDD:128933
		DM3	3544..3601	CDD:128933
		THAP	3622..>3673	CDD:461662
		DM3	3690..3748	CDD:128933
thap7	NP_001429232.1	None