DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10462 and STP1

DIOPT Version :9

Sequence 1:	NP_609996.2	Gene:	CG10462 / 35260	FlyBaseID:	FBgn0032815	Length:	812	Species:	Drosophila melanogaster
Sequence 2:	NP_010751.4	Gene:	STP1 / 852074	SGDID:	S000002871	Length:	519	Species:	Saccharomyces cerevisiae

Alignment Length:	282	Identity:	65/282 - (23%)
Similarity:	97/282 - (34%)	Gaps:	105/282 - (37%)

- Green bases have known domain annotations that are detailed below.

  Fly   542 CNVLKVVLMPSKILSQDSANAATQRVHVPLNPQTPVPPPELPNTVNLPLLLSK-----TSAPL-- 599
            |:|:.        .|.|.::..|. :.:.|:|:.     .:.:.||...||..     |.||:
Yeast    80 CSVIP--------CSMDVSDLNTP-ISITLSPEN-----RIKSEVNAKSLLGSRPEQDTGAPIKM 130

  Fly   600 -TGQTSALSNVPVNKGLSPTSINIEKPKVSKKPKKNQSFQCTECLKVFTTFGALRIHKSIHTGEL 663
             ||.||           ||.|.:...|:.|.|...|                          ||.
Yeast   131 STGVTS-----------SPLSPSGSTPEHSTKVLNN--------------------------GEE 158

  Fly   664 PYQCSYCDKRFRTPGQVRVHHRRHTGEKPFKCKI----------C--SLDFTHRETLISHL-SRH 715
            .:.|.|||..||..|.:..|.::|..||.:.|..          |  |..|:.|:|..:|| :||
Yeast   159 EFICHYCDATFRIRGYLTRHIKKHAIEKAYHCPFFNSATPPDLRCHNSGGFSRRDTYKTHLKARH 223

  Fly   716 I----GMK---RYK----CYGCDKYFVVV-----------------SGLRAHRRLRPDTCGKVKF 752
            :    |:|   |.|    |..|.:||..:                 .|.......|.....|:|
Yeast   224 VLYPKGVKPQDRNKSSGHCAQCGEYFSTIENFVENHIESGDCKALPQGYTKKNEKRSGKLRKIK- 287

  Fly   753 TARAHGPRV----RVIRGEVVF 770
            |:..|...:    .|:..:|:|
Yeast   288 TSNGHSRFISTSQSVVEPKVLF 309

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10462	NP_609996.2	C2H2 Zn finger	137..157	CDD:275371
		C2H2 Zn finger	165..186	CDD:275371
		C2H2 Zn finger	639..659	CDD:275368	0/19 (0%)
		zf-H2C2_2	651..676	CDD:290200	7/24 (29%)
		C2H2 Zn finger	667..687	CDD:275368	8/19 (42%)
		zf-H2C2_2	680..704	CDD:290200	8/35 (23%)
		C2H2 Zn finger	695..715	CDD:275368	8/32 (25%)
		C2H2 Zn finger	723..742	CDD:275368	5/35 (14%)
STP1	NP_010751.4	zf-C2H2	160..182	CDD:395048	8/21 (38%)
		C2H2 Zn finger	162..182	CDD:275368	8/19 (42%)
		C2H2 Zn finger	190..220	CDD:275368	7/29 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24396
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100