Protein Alignment CG10462 and Zfp236

DIOPT Version :10

• Sequence 1: NP_609996.2
• Gene: CG10462 / 35260
• FlyBaseID: FBgn0032815
• Length: 812
• Species: Drosophila melanogaster
• Sequence 2: NP_001414135.1
• Gene: Zfp236 / 291409
• RGDID: 1309670
• Length: 1848
• Species: Rattus norvegicus
• Alignment Length: 858
• Identity: 169/858 - (19%)
• Similarity: 305/858 - (35%)
• Gaps: 210/858 - (24%)

  Fly    69 ESEDNPNPKHCDICQYKFKSQQDISSHRVHHE--------MNLHFCRLGCGIWLDTLEKILEHEY 125
            |.|.|..|..||.|...|..:.:::.|:..|.        .|..|.|:.     .....|:.||.
  Rat    60 EHEQNDKPHRCDQCPQTFNVEFNLTLHKCTHNAEDPVCPVCNKKFSRVA-----SLKAHIMLHEK 119

  Fly   126 RQHFQPGRVLCCRVC--DFMANSADDLASHMQKH--------IYVYRFVCSICRRHFESKQSLNL 180
            .::      |.|..|  :|..:|  .||.||::|        ::    .|..|::.||:...|..
  Rat   120 EEN------LICSECGDEFTLHS--QLAIHMEEHRQELANNRVH----TCKACKKEFETSPELKE 172

  Fly   181 HRKQ--------SQDFCSLLDFRKGSSSKPELVAVSTPVPEESNCYVQIK--EEPLNAEEADRML 235
            |.|.        ::.:...:| |.|.:........:...|.:...:::|.  |.|....|..: .
  Rat   173 HMKTHCKVRASGTRSYNRNID-RSGFTYSCPHCGKTFQKPSQLTRHIRIHTGERPFKCSECGK-A 235

  Fly   236 LEDNPPLNVKLEPQDEEMP------------------DVSRIKEEQSNGSVWTAIHTPLRNKLRL 282
            ......|...:.....|.|                  .|.|:..|..||..:.........| .|
  Rat   236 FNQKGALQTHMIKHTGEKPHACAFCPAAFSQKGNLQSHVQRVHSEVKNGPTYNCTECSCVFK-SL 299

  Fly   283 PALATTKNQMHL------KPGVKRNGLLTSNV-ESLNKKSNHSVISDDANIPISNQEPSNSSIAA 340
            .:|.|..::||:      ....:...::|:.: ::|..:...:.:|.     :|.::  ||....
  Rat   300 GSLNTHISKMHMGGPPNPSSSTETAHVITATIFQTLPLQQVEAQVSS-----VSGEQ--NSQAVT 357

  Fly   341 NILKVLPSNCMVIKLPPNTKIFKTPGQAPAAPKDSPTVTLSGTENSTNFIKIPKTISISTVGSMG 405
            ::::.|    :.:..|       .|.:|..:|:....::::...|.....:..:...:|::....
  Rat   358 DVIQQL----LELSEP-------GPVEAQQSPQSGRQLSVTVGINQDILQQALENSGLSSLPVAA 411

  Fly   406 NP----HASAKTVQPTQTHSRS-SCFLVDSFNNSKSR----PESMKIINEFRNQIRSIEKTLP-L 460
            .|    ||...||.....|:.| |....|..:..:.:    ||..:     :.:.:.::|..| |
  Rat   412 PPSDCSHAQTSTVSSQSPHTSSVSAEQADPMDAEQEKGQESPEKAE-----KKEKKILKKKSPFL 471

  Fly   461 PGTVLQSSKVTMDESTSSPMDAPKPVELMLNPSALMVARELEIQYPLYRFMWTCPLCQRMFEKHC 525
            ||::.:.:.|..........:..||.:|:         |.:.|.  .:...:.||.|.|.|....
  Rat   472 PGSIREENGVRWHVCPYCTKEFRKPSDLV---------RHIRIH--THEKPFKCPQCFRAFAVKS 525

  Fly   526 AFRAHLTNKHDLTDEKCNVLKVVLMPSKILSQDSANAATQRVHVPLNPQTPVPPPELPNTVNLPL 590
            ...||:.....:...||          :...:..:.:.:.:||:.|:  |.|.|...|:...
  Rat   526 TLTAHIKTHTGIKAFKC----------QYCMKSFSTSGSLKVHIRLH--TGVRPFACPHCDK--- 575

  Fly   591 LLSKTSA-----------------------PLTGQ----TSALSNVPVNKGLSPTSINIEKPKVS 628
             ..:||.                       |:.|:    ::.:.::|:.:.:..|.:.:.:|
  Rat   576 -KFRTSGHRKTHVASHFKHTELRKMRQQRKPVKGRAGKSSAPVPDIPLQEPILITDLGLIQP--- 636

  Fly   629 KKPKKNQSFQCTECLKVF-TTFGALRIHKSIHTGELPYQCSYCDKRFRTPGQVRVHHRRHTGEKP 692
              ..|||.||     ..| ..||        :..:.||:|.||.:.::....::.|.|.||||||
  Rat   637 --IPKNQFFQ-----NYFNNNFG--------NEADRPYKCFYCHRAYKKSCHLKQHIRSHTGEKP 686

  Fly   693 FKCKICSLDFTHRETLISHLSRHIGMKRYKCYGCDKYFVVVSGLR----AHRRLRPDTCG----- 748
            |||..|...|.....|.:|:..|.|:|.:||..|:..|.....||    .|..|||..|.
  Rat   687 FKCSQCGRGFVSAGVLKAHVRTHTGLKSFKCLICNGAFTTGGSLRRHMGIHNDLRPYMCPYCQKT 751

  Fly   749 -KVKFTARAHGPRVRVIRGEVVFQYHPEHNGYLRSED--------------PLNI----LSQRDQ 794
             |.....:.|   ::..|.|:..|...........|:              |:.|    |.|..:
  Rat   752 FKTSLNCKKH---MKTHRYELAQQLQQHQEASSMDEESTVDQQSIQVSAPMPVEIESAELQQTPE 813

  Fly   795 TNSTPPETAIDTG 807
            |.:..||:.::.|
  Rat   814 TVAADPESILELG 826

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10462	NP_609996.2	C2H2 Zn finger	137..157	CDD:275371	8/21 (38%)
		C2H2 Zn finger	165..186	CDD:275371	7/28 (25%)
		KREPA	<549..>664	CDD:483960	22/142 (15%)
		C2H2 Zn finger	639..659	CDD:275368	3/20 (15%)
		zf-H2C2_2	651..676	CDD:463886	5/24 (21%)
		C2H2 Zn finger	667..687	CDD:275368	5/19 (26%)
		zf-H2C2_2	681..704	CDD:463886	13/22 (59%)
		C2H2 Zn finger	695..715	CDD:275368	5/19 (26%)
		C2H2 Zn finger	723..742	CDD:275368	6/22 (27%)
Zfp236	NP_001414135.1	None