DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Lar and PTP1

DIOPT Version :9

Sequence 1:NP_001260594.1 Gene:Lar / 35259 FlyBaseID:FBgn0000464 Length:2032 Species:Drosophila melanogaster
Sequence 2:NP_010051.1 Gene:PTP1 / 851368 SGDID:S000002389 Length:335 Species:Saccharomyces cerevisiae


Alignment Length:298 Identity:93/298 - (31%)
Similarity:140/298 - (46%) Gaps:75/298 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly  1787 PCNKHKNRLVHILPYESSRVYLTPIHGIEGSDYVNASFI----------DGYRYRSAYIAAQGPV 1841
            |.|..:||.|:|:|||.:||:|..   :.|:||:|||::          .||     |||.|||.
Yeast    50 PRNDARNRYVNIMPYERNRVHLKT---LSGNDYINASYVKVNVPGQSIEPGY-----YIATQGPT 106

  Fly  1842 QDAAEDFWRMLWEHN----STIVVMLTKLKEMGREKCFQYWPH---------------------- 1880
            :...:.||:|.: ||    :.::||:|.|.|..||||:||||.                      
Yeast   107 RKTWDQFWQMCY-HNCPLDNIVIVMVTPLVEYNREKCYQYWPRGGVDDTVRIASKWESPGGANDM 170

  Fly  1881 ---ERSVRYQYYVVDPIAEYNMPQYKLREFKV--TDARDGSSRTVRQFQFIDWPEQGVPKSGEGF 1940
               ...::.::..|..:.:|    |.:.:.|:  ||...|..:||..|.|..|.:...|:.....
Yeast   171 TQFPSDLKIEFVNVHKVKDY----YTVTDIKLTPTDPLVGPVKTVHHFYFDLWKDMNKPEEVVPI 231

  Fly  1941 IDFIGQVHKTKEQFGQDGPITVHCSAGVGRSGVFITLS-IVLERMQYEGVLD------------- 1991
            ::.....|...   .:..||.|||||||||:|.||.|. ::.:.:.::.:.:             
Yeast   232 MELCAHSHSLN---SRGNPIIVHCSAGVGRTGTFIALDHLMHDTLDFKNITERSRHSDRATEEYT 293

  Fly  1992 ---VFQTVRILRSQRPAMVQTEDQYHFCYRAALEYLGS 2026
               :.|.|..|||||..||||:||:.|.|.|| :||.|
Yeast   294 RDLIEQIVLQLRSQRMKMVQTKDQFLFIYHAA-KYLNS 330

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LarNP_001260594.1 Ig 35..129 CDD:299845
I-set 36..129 CDD:254352
IG_like 146..227 CDD:214653
Ig 159..228 CDD:299845
I-set 234..318 CDD:254352
Ig3_RPTP_IIa_LAR_like 249..317 CDD:143216
fn3 324..404 CDD:278470
FN3 423..514 CDD:238020
FN3 520..610 CDD:238020
FN3 616..707 CDD:238020
FN3 712..810 CDD:238020
FN3 832..907 CDD:238020
FN3 914..1005 CDD:238020
FN3 1012..1101 CDD:238020
fn3 1106..1198 CDD:278470
PTPc 1476..1731 CDD:214550
PTPc 1503..1731 CDD:238006
PTPc 1763..2022 CDD:214550 90/292 (31%)
PTPc 1791..2022 CDD:238006 88/288 (31%)
PTP1NP_010051.1 COG5599 1..335 CDD:227886 93/298 (31%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 133 1.000 Domainoid score I1104
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm46470
orthoMCL 1 0.900 - - OOG6_100623
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R3031
SonicParanoid 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
54.840

Return to query results.
Submit another query.