Protein Alignment Lar and ptpn2b

DIOPT Version :10

• Sequence 1: NP_001260594.1
• Gene: Lar / 35259
• FlyBaseID: FBgn0000464
• Length: 2032
• Species: Drosophila melanogaster
• Sequence 2: NP_997819.1
• Gene: ptpn2b / 561613
• ZFINID: ZDB-GENE-030909-8
• Length: 393
• Species: Danio rerio
• Alignment Length: 308
• Identity: 105/308 - (34%)
• Similarity: 154/308 - (50%)
• Gaps: 35/308 - (11%)

  Fly  1479 QEYESIEPGQQFTWDNSNLE----------------HNKSKNRYANVTAYDHSRVQLPAVEGVVG 1527
            ||:|.|:  .:..|.|..||                .|:.:|||.:|:.:|||||:|...|
Zfish     3 QEFEDID--SEGRWQNIYLEIRNQSHECAFKVAKYPENRIRNRYRDVSPFDHSRVKLENTE---- 61

  Fly  1528 SDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELKTATIVMMTRLEERTRIKCDQYWPTR 1592
            :|||||:..........|:.|||||:.|...||.|.||.||..::|:.|:.|:...||.|||||:
Zfish    62 NDYINASLVVMEEAQRRYILTQGPLRNTCGHFWLMIWEQKTKAVIMLNRVIEKGSEKCAQYWPTQ 126

  Fly  1593 GTETYG----QIFVTITETQELATYSIRTFQLCRQGFNDRREIKQLQFTAWPDHGVPDHPAPFLQ 1653
            ......    :..||:......:.|:.|..:|......:.|||....:|.|||.|||:.||.||.
Zfish   127 EEREMSFRDTRFVVTLVSEDVKSYYTTRVLELQNANTGETREIYHFHYTTWPDFGVPESPASFLN 191

  Fly  1654 FLRRCR--ALTPPESGPVIVHCSAGVGRTGCYIVIDS---MLERMKHEKIIDIYGHVTCLRAQRN 1713
            ||.:.|  .....|.||.:||||||:||:|.:.::|:   ::::.|...::||...:..:|..|.
Zfish   192 FLFKVRESGSLGMEQGPAVVHCSAGIGRSGTFSLVDTCLVLMDKRKDPLLVDIKKILLDMRKYRM 256

  Fly  1714 YMVQTEDQYIFIHDAILEA--IICGVTEVPA--RNLHTHLQKLLITEP 1757
            .::||.||..|.:.|:||.  .|.|.:.|..  |.|....|:.|...|
Zfish   257 GLIQTPDQLRFSYMAVLEGAKYIMGDSSVQKQWRELSREDQEPLSESP 304

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lar	NP_001260594.1	I-set	36..129	CDD:400151
		Ig strand B	53..57	CDD:409353
		Ig strand C	66..70	CDD:409353
		Ig strand E	93..97	CDD:409353
		Ig strand F	108..113	CDD:409353
		Ig strand G	122..125	CDD:409353
		Ig	141..228	CDD:472250
		Ig strand B	157..161	CDD:409353
		Ig strand C	170..174	CDD:409353
		Ig strand E	192..196	CDD:409353
		Ig strand F	206..211	CDD:409353
		Ig strand G	218..221	CDD:409353
		IgI_3_RPTP_IIa_LAR_like	237..319	CDD:409401
		Ig strand A	237..239	CDD:409401
		Ig strand A'	244..248	CDD:409401
		Ig strand B	251..259	CDD:409401
		Ig strand C	264..270	CDD:409401
		Ig strand C'	272..274	CDD:409401
		Ig strand D	277..281	CDD:409401
		Ig strand E	286..291	CDD:409401
		Ig strand F	298..305	CDD:409401
		Ig strand G	309..318	CDD:409401
		FN3	322..411	CDD:238020
		FN3	<382..747	CDD:442628
		FN3	712..810	CDD:238020
		FN3	832..898	CDD:214495
		FN3	<867..1269	CDD:442628
		fn3	914..998	CDD:394996
		R-PTPc-LAR-1	1498..1735	CDD:350401	90/263 (34%)
		R-PTP-LAR-2	1784..2021	CDD:350402
ptpn2b	NP_997819.1	PTP_DSP_cys	15..272	CDD:475123	89/260 (34%)