DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lar and Ptpmeg2

DIOPT Version :9

Sequence 1:NP_001260594.1 Gene:Lar / 35259 FlyBaseID:FBgn0000464 Length:2032 Species:Drosophila melanogaster
Sequence 2:NP_572576.1 Gene:Ptpmeg2 / 31907 FlyBaseID:FBgn0028341 Length:827 Species:Drosophila melanogaster


Alignment Length:292 Identity:112/292 - (38%)
Similarity:160/292 - (54%) Gaps:19/292 - (6%)


- Green bases have known domain annotations that are detailed below.


  Fly  1456 PIPISEFANHIERLKSNDNQKFSQEYESI-EPGQQFTWDNSNLEHNKSKNRYANVTAYDHSRVQL 1519
            |.||.:.   ::.:|........:||..| ....:.|:.::.:..|.:||||.:|..||||||.|
  Fly   515 PKPIDQI---VQMVKQRGRHGLIKEYADIRNRAPEGTFLHARMRANLTKNRYTDVLCYDHSRVVL 576

  Fly  1520 PAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELKTATIVMMTRLEERTRIK 1584
            ...:|...|||||||:.|||::.|||::|||||.:|..|||||.||.....|||.||:.||.|:|
  Fly   577 AHEDGDEPSDYINANFVDGYKQKNAYISTQGPLPKTSQDFWRMIWEQHCLVIVMTTRVMERGRVK 641

  Fly  1585 CDQYW-PTRGTE-TYGQIFVTITETQELATYSIRTFQLCRQGFNDRREIKQLQFTAWPDHGVPDH 1647
            |.||| ||..:. .:|...|.....:....|.:.:.:|.....::.|.:...|||:|||:|||..
  Fly   642 CGQYWEPTEESSLEFGDYHVRTISVECNEDYMVASLELRNIKTDEIRNVSHWQFTSWPDYGVPSS 706

  Fly  1648 PAPFLQFLRRCRALTP-------------PESGPVIVHCSAGVGRTGCYIVIDSMLERMKHEKII 1699
            ....|.||::.|....             |...|::||||||:||||.:|.:|..:.|::.....
  Fly   707 AMAMLNFLQKVREKQAQLVQGLGDTWAGHPRGPPIVVHCSAGIGRTGTFITLDICISRLEDVGTA 771

  Fly  1700 DIYGHVTCLRAQRNYMVQTEDQYIFIHDAILE 1731
            ||.|.|..:|:||.|.:|..|||:|.|.|::|
  Fly   772 DIRGTVEKIRSQRAYSIQMPDQYVFCHLALIE 803

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LarNP_001260594.1 Ig 35..129 CDD:299845
I-set 36..129 CDD:254352
IG_like 146..227 CDD:214653
Ig 159..228 CDD:299845
I-set 234..318 CDD:254352
Ig3_RPTP_IIa_LAR_like 249..317 CDD:143216
fn3 324..404 CDD:278470
FN3 423..514 CDD:238020
FN3 520..610 CDD:238020
FN3 616..707 CDD:238020
FN3 712..810 CDD:238020
FN3 832..907 CDD:238020
FN3 914..1005 CDD:238020
FN3 1012..1101 CDD:238020
fn3 1106..1198 CDD:278470
PTPc 1476..1731 CDD:214550 107/270 (40%)
PTPc 1503..1731 CDD:238006 102/242 (42%)
PTPc 1763..2022 CDD:214550
PTPc 1791..2022 CDD:238006
Ptpmeg2NP_572576.1 CRAL_TRIO_N <114..144 CDD:215024
SEC14 170..314 CDD:238099
Y_phosphatase 557..803 CDD:278528 103/245 (42%)
PTPc 559..803 CDD:238006 102/243 (42%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C45443556
Domainoid 1 1.000 163 1.000 Domainoid score I1235
eggNOG 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 1 1.000 - - otm2866
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - P PTHR19134
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
54.940

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