Protein Alignment Lar and ZK616.65

DIOPT Version :9

• Sequence 1: NP_001260594.1
• Gene: Lar / 35259
• FlyBaseID: FBgn0000464
• Length: 2032
• Species: Drosophila melanogaster
• Sequence 2: NP_001293838.1
• Gene: ZK616.65 / 24105295
• WormBaseID: WBGene00235383
• Length: 543
• Species: Caenorhabditis elegans
• Alignment Length: 507
• Identity: 136/507 - (26%)
• Similarity: 203/507 - (40%)
• Gaps: 87/507 - (17%)

  Fly  1309 TNRKLEREKRYRIFVRAVVDTPQKHLYTSSPFSEFLSLDMREAPPGERPHRPDPNWPAEPEVSVN 1373
            :|.|...:|..|..|:.||.....|:    |||.  |......||....:|.    ..:.:|...
 Worm    66 SNSKGSNDKNKRKSVQEVVKKVVNHI----PFSP--SKQPTSTPPVSEGNRK----RLQTKVVER 120

  Fly  1374 RNKDEPEILWVVLPLMVSTFI------------------VSTALIVLCVVKRRRQPCKTPDQAAV 1420
            .|:.|.|         :.:|:                  :|.:...:.....:|.|.|.......
 Worm   121 SNQIESE---------MDSFVKKIEPNERRATQYNHSNSLSGSNEAVPPGNVKRSPQKATHPIRT 176

  Fly  1421 TRPLMAAD--------------LGAGPTPSDPVDMRRLNFQTPGMISHPPIPIS----------- 1460
            ||.|:..|              ...|...:|....||.:.......|.....||
 Worm   177 TRSLIGLDGETEAVYSKTSKTSPDKGKVTADSPRSRRTSKSLEENSSEANDSISLADDEETREAY 241

  Fly  1461 -----EFANHIERLKSNDNQKFSQEYESI---EPGQQFTWDNSNLEHNKSKNRYANVTAYDHSRV 1517
                 :||...:::..:|   |.||:.::   .|....|..|..:  |..||||.|:...|.|||
 Worm   242 RKLFKDFAMSSQKMTLDD---FKQEFSNLPGDPPSDLCTAFNQPV--NNKKNRYLNIPCLDISRV 301

  Fly  1518 QLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWRMCWELKTATIVMMTRLEERTR 1582
            ||..:.....:|||:|||.........|:.||||.:||..|||||.|:..|..|||:.:..|..|
 Worm   302 QLKVMPNKNSTDYIHANYIRSPFLKRGYILTQGPKKETRADFWRMIWQENTTAIVMLCQFTETNR 366

  Fly  1583 IKCDQYWPTRGTETYGQIFVTITETQELATY--SIRTFQLCRQGFNDRREIKQLQFTAWPDHGVP 1645
            .||.:|:| |......| |..::.:.|.:|.  |:.|.:|......:.|.|....:..|||..||
 Worm   367 EKCAEYFP-RNAHCCLQ-FDKMSVSYEDSTVNKSLVTTRLNLSYEGETRLITHWLWKEWPDWQVP 429

  Fly  1646 DHPAPFLQFLRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDSMLERM-KHEKIIDIYGHVTCLR 1709
            ......|:.||:.||    .|.|.::||||||||:|..:.::..|:.: .|..:.||...|:.||
 Worm   430 GSSEVMLKILRKIRA----RSTPPVIHCSAGVGRSGTLMAVEIALQSIHSHFTLPDIKQIVSHLR 490

  Fly  1710 AQ-RNYMVQTEDQYIFIHDAILEAIIC--GVTEVPARNLHTHLQKLLITEPG 1758
            .. |...|||..||:.|...:|:..:.  .:||..|...:...::.|.:..|
 Worm   491 VTGRAASVQTLQQYMLIWKVLLDFGVAYKQITEELAEKFNATYRRSLRSNNG 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lar	NP_001260594.1	Ig	35..129	CDD:299845
		I-set	36..129	CDD:254352
		IG_like	146..227	CDD:214653
		Ig	159..228	CDD:299845
		I-set	234..318	CDD:254352
		Ig3_RPTP_IIa_LAR_like	249..317	CDD:143216
		fn3	324..404	CDD:278470
		FN3	423..514	CDD:238020
		FN3	520..610	CDD:238020
		FN3	616..707	CDD:238020
		FN3	712..810	CDD:238020
		FN3	832..907	CDD:238020
		FN3	914..1005	CDD:238020
		FN3	1012..1101	CDD:238020
		fn3	1106..1198	CDD:278470
		PTPc	1476..1731	CDD:214550	92/261 (35%)
		PTPc	1503..1731	CDD:238006	85/231 (37%)
		PTPc	1763..2022	CDD:214550
		PTPc	1791..2022	CDD:238006
ZK616.65	NP_001293838.1	PTPc	260..513	CDD:214550	92/260 (35%)
		PTPc	286..513	CDD:238006	85/232 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910