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Protein Alignment Lar and Ptprj

DIOPT Version :10

Sequence 1:	NP_001260594.1	Gene:	Lar / 35259	FlyBaseID:	FBgn0000464	Length:	2032	Species:	Drosophila melanogaster
Sequence 2:	XP_006499054.1	Gene:	Ptprj / 19271	MGIID:	104574	Length:	1351	Species:	Mus musculus

Alignment Length:	1605	Identity:	337/1605 - (20%)
Similarity:	537/1605 - (33%)	Gaps:	580/1605 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly   258 AVGSPMPHVKWMK----GSEDLTPENEMPIGRNVLQLINIQESANYTCIAASTLGQIDSVSVVKV 318
            ||.||...:...|    |:.:...||:|.  .|:...:..|.|.|.|.::..|......:||...
Mouse   160 AVVSPTSVLLTWKHNDSGASECRIENKME--SNLTFPVKNQTSCNITGLSPGTSYTFSIISVTTN 222

  Fly   319 QSL-------PTAPTDVQISEVTATSVRLEWSYKGP--------EDLQYY----VIQYKPKNANQ 364
            ::|       |...:|:.::.|..|..||.||....        |:|..:    :...||...|.
Mouse   223 ETLNKTITTEPWPVSDLHVTSVGVTQARLTWSNANGTASYRMLIEELTTHSSVNISGLKPGTNNS 287

  Fly   365 -AFSEISGIITMYYVVRALSPYTEYEFYV-------------IAVNNIGR---------GPPSA- 405
             ||.|              |..|:.:|.|             |.|.|:.:         .|||.
Mouse   288 FAFPE--------------SNETQADFAVAEEVPADANGTKRIPVTNLSQLHKNSLVSVDPPSGQ 338

  Fly   406 -------------PAT---CTTGDFSFGGTKMESAPRN------------VQVRTLSSSTMVITW 442
                         |.|   .|....:..||  |..|||            |:...:|:|:|.:||
Mouse   339 DPSLTEILLTDLKPDTQYNATIYSQAANGT--EGQPRNKVFKTNSTQVSDVRAMNISASSMTLTW 401

  Fly   443 EPPETPNGQVTG--YKVYYTTNSNQPEASWNSQMVDNSELTTVSELTPHAIYTVRVQAYTSMGAG 505
            :  ...:|..|.  ||::....::..     :|.|:.:| ..:..|:...:|.:.|..:.....|
Mouse   402 K--SNYDGSRTSIVYKIHVAGGTHSV-----NQTVNKTE-AIILGLSSSTLYNITVHPFLGQTEG 458

  Fly   506 PMSTP--VQVKAQQGVPSQPSNFRATDIGETAVTLQWTKPTHSSENIVHYELYWNDTYANQAHHK 568
               ||  :||...   |.|.|:||.|::...|:.|.|     .|.:...:|::.... ..:.|..
Mouse   459 ---TPGFLQVYTS---PDQVSDFRVTNVSTRAIGLAW-----RSNDSKSFEIFIKQD-GGEKHRN 511

  Fly   569 RISNSEAYTLDGLYPDTLYYIWLAARSQRG--------EGATTPPIPVRTKQYGAPPRNITAIAT 625
            ..:.:::|.::.|.|.|.|:..:..|...|        .|:|.|          :...:|..:..
Mouse   512 ASTGNQSYMVEDLKPGTSYHFEIIPRGPDGTEGLSSTVNGSTDP----------SAVTDIRVVNI 566

  Fly   626 SSTTISLSWLPPPVERSNGRIIYYKVFFVEVGREDDEATTMTLNMTSIVLD----ELKRWTEYKI 686
            |:|.:.|.|                       :..|:|:..|.:   :||:    .:.|....:.
Mouse   567 STTEMQLEW-----------------------QNTDDASGYTYH---LVLESKSGSIIRTNSSQK 605

  Fly   687 WVLAGTSVGDGPRSHPIILRTQEDVPG---------DPQDVKATPLN--STSIHVSWKPPLEKDR 740
            |:..| |:..|...:..|....:.:.|         .|..|....:|  :|:..:.||   .:|.
Mouse   606 WITVG-SLTPGTLYNVTIFPEVDQIQGISNSITQYTRPSSVSHIEVNTTTTTAAIRWK---NEDA 666

  Fly   741 NGIIRGYHIHAQELRDEG---KGFLNEPFKFDVVDTLEFNVTGLQPDTKYSIQVAALTRKGDGDR 802
            ......|.:...:..|..   ..|..:|         ...:..|.|...|::::  ||:.|||..
Mouse   667 ASASYAYSVLILKTGDGSNVTSNFTKDP---------SILIPELIPGVSYTVKI--LTQVGDGTT 720

  Fly   803 SAAIVVKTPGG----VPVRPTVSL--KIMEREPIVSIELEWERPAQTYGELRGYRLRWGVKDQAL 861
            |.     .||.    ....|..|.  :::.:||  ::.|:|..|   :|...|:.|  ||:..
Mouse   721 SL-----VPGWNLFCTEPEPVTSFHCEVVPKEP--ALVLKWACP---FGMYTGFEL--GVRSD-- 771

  Fly   862 KEEMLSGPQMTKKRFDNLERGVEYEFRV-------AGSNHIGIGQETVKIFQTPEGTPGGPPSNI 919
                 |...||  |.:|.....:.|.|.       :.|.:|.|...:.       |....|..||
Mouse   772 -----SWDNMT--RLENCTSDDDTECRTEVAYLNFSTSYNISIATLSC-------GKMALPAQNI 822

  Fly   920 TIRFQTPDVLCVT--WDPPTREHRNGIITRYDVQFHKKIDHGLGSERNMTLRKAVFTNLEENTEY 982
                      |.|  .||||.:....|.:    ..|..:             |..|:..|.:..
Mouse   823 ----------CTTGITDPPTPDGSPNITS----VSHNSV-------------KVKFSGFEASHG- 859

  Fly   983 IFRVRAY-----TKQGAGPFSDKLIVETERDMGRAPMSLQAEATSEQTAEIWWEPVTSRGKLLGY 1042
              .::||     |.:.|.|.:| ::..|..|..|...
Mouse   860 --PIKAYAVILTTGEAAQPSAD-VLKYTYEDFKRGAS---------------------------- 893

  Fly  1043 KIFYTMTAVEDLDDWQTKTVGLTESADLVNLEKFAQYAVAIAARFKNGLGRLSEKVTVRIKPEDV 1107
                        |.:.|..:.:.|......|.:...|.:
Mouse   894 ------------DTYVTYLIRIEEKGQSQGLSEVLNYEI-------------------------- 920

  Fly  1108 PLNLRAHDVSTHSMTLSWSPPIRLTPVNYKISFDAMKVFVDSQGFSQTQIVPKREIILKHYVKTH 1172
                   ||...|.||.:          |.
Mouse   921 -------DVGNQSTTLGY----------YN----------------------------------- 933

  Fly  1173 TINELSPFTTYNVNVSAIPSDYSYRPPTKITVTTQMAAPQPMVKPDFYGVVNGEEILVILPQASE 1237
              ..|.|..:|...|:..         |.||...|..           |::||:|
Mouse   934 --GRLEPLGSYRACVAGF---------TNITYNLQND-----------GLINGDE---------- 966

  Fly  1238 EYGPISHYYLVVVPEDKSNLHKIPDQFLTDDLLPGRNKPERPNAPYIAAKFPQRSIPFTFHLGSG 1302

Mouse   967 ----------------------------------------------------------------- 966

  Fly  1303 DDYHNFTNRKLEREKRYRIFVRAVVDTPQKHLYTSSPFSEFLSLDMREAPPGERPHRPDPNWPAE 1367
             .|.:|                             ||:||.:.|                  |.:
Mouse   967 -SYVSF-----------------------------SPYSEAVFL------------------PQD 983

  Fly  1368 PEVSVNRNKDEPEILWVVLPLMVSTFIVSTALIVLCVVKRRRQPCKTPDQAAVTRPLMAADLGAG 1432
            |.|          |...|...:.....: ||:......:::|...|
Mouse   984 PGV----------ICGAVFGCIFGALAI-TAVGGFIFWRKKRTDAK------------------- 1018

  Fly  1433 PTPSDPVDMRRLNFQTPGMISHPPIPISEFANHIERLKSNDNQKFSQEYESIE-PGQQFTWDNSN 1496
               ::.|...::..:...:|.     :..|..:.::.:::.|..|::|||.:: .|.......:.
Mouse  1019 ---NNEVSFSQIKPKKSKLIR-----VENFEAYFKKQQADSNCGFAEEYEDLKLIGISLPKYTAE 1075

  Fly  1497 LEHNKSKNRYANVTAYDHSRVQLPAVEGVVGSDYINANYCDGYRKHNAYVATQGPLQETFVDFWR 1561
            :..|:.||||.||..||.|||:| :|:.....|||||||..||.....::||||||..|..||||
Mouse  1076 IAENRGKNRYNNVLPYDISRVKL-SVQTHSTDDYINANYMPGYHSKKDFIATQGPLPNTLKDFWR 1139

  Fly  1562 MCWELKTATIVMMTRLEERTRIKCDQYWPTRGTETYGQIFVTITETQELATYSIRTFQLCRQGFN 1626
            |.||.....|||:|:..|:.|.||::|||::..:.||.|.|.:|....|..::||.|.:.....:
Mouse  1140 MVWEKNVYAIVMLTKCVEQGRTKCEEYWPSKQAQDYGDITVAMTSEVVLPEWTIRDFVVKNMQNS 1204

  Fly  1627 DRREIKQLQFTAWPDHGVPDHPAPFLQF---LRRCRALTPPESGPVIVHCSAGVGRTGCYIVIDS 1688
            :...::|..||:||||||||.....:.|   :|......|||| |::|||||||||||.:|.||.
Mouse  1205 ESHPLRQFHFTSWPDHGVPDTTDLLINFRYLVRDYMKQIPPES-PILVHCSAGVGRTGTFIAIDR 1268

  Fly  1689 MLERMKHEKIIDIYGHVTCLRAQRNYMVQTEDQYIFIHDAILEAI 1733
            ::.::::|..:|:||.|..||..|..||||||||:|::..:|:.|
Mouse  1269 LIYQIENENTVDVYGIVYDLRMHRPLMVQTEDQYVFLNQCVLDII 1313

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.