Protein Alignment Lar and ptpn9a

DIOPT Version :10

• Sequence 1: NP_001260594.1
• Gene: Lar / 35259
• FlyBaseID: FBgn0000464
• Length: 2032
• Species: Drosophila melanogaster
• Sequence 2: XP_005163030.1
• Gene: ptpn9a / 100526653
• ZFINID: ZDB-GENE-101027-1
• Length: 571
• Species: Danio rerio
• Alignment Length: 374
• Identity: 128/374 - (34%)
• Similarity: 189/374 - (50%)
• Gaps: 49/374 - (13%)

  Fly  1687 DSMLERMKHEKIIDIYGHVT----------CLRAQ-RNYMVQTEDQYIFIHDAILEAIICGVTEV 1740
            :.:.||::..|:.|:..|:.          ||... .|:.:|...:.....|.:.|.:     .:
Zfish   199 EKLRERVQMVKMADLRQHLPRDCLPEHLGGCLPLDVHNWNLQLLSEQNGRVDPVDELV-----GI 258

  Fly  1741 PARNLHTH--------LQKLLITEPGETISGMEVEFKKLSNVKMDSSKFVTANLPCNKHKNRLVH 1797
            |..|...|        |.:|:........||:.:|:::|.. :.....|..|....|:.:||...
Zfish   259 PLENTSIHTPGAEAMSLAELMAHLNRAQRSGIYLEYEELRR-EQPPGTFTCALAAHNQERNRYGD 322

  Fly  1798 ILPYESSRVYLTPIHGIEGSDYVNASFIDGYRYRSAYIAAQGPVQDAAEDFWRMLWEHNSTIVVM 1862
            :|..:.:||.|..... |.|||:||||:|||:.::|||..|||::....|||||:||.|..::||
Zfish   323 VLCLDQTRVRLKARRN-ERSDYINASFMDGYKQKNAYIGTQGPLEKTYGDFWRMVWEQNVLVIVM 386

  Fly  1863 LTKLKEMGREKCFQYWPHERSVRYQY-YV------VDPIAEYNMPQYKLREFKVTDARDGSSRTV 1920
            .|:..|.||.||.||||.|...:..| |:      ||..|.||....:|...:..:     .|.|
Zfish   387 TTRTDEGGRRKCGQYWPQEEGGQEVYGYIAVVNHRVDNHAHYNQTTLELHNTETFE-----QRQV 446

  Fly  1921 RQFQFIDWPEQGVPKSGEGFIDFIGQV-HKTK---EQFGQD-------GPITVHCSAGVGRSGVF 1974
            ..|||:.||:.|||.|....|||:|.| |:.:   :.||..       .|:.||||||:||:|.|
Zfish   447 THFQFLSWPDYGVPSSAVSLIDFLGAVKHQQQWAVQAFGTQWRGHPLGPPMVVHCSAGIGRTGTF 511

  Fly  1975 ITLSIVLERMQYEGVLDVFQTVRILRSQRPAMVQTEDQYHFCYRAALEY 2023
            ..|.|.|.::|..|.|::.||||.:||||...:||.:||:||:.|.||:
Zfish   512 CALDICLSQLQDVGTLNICQTVRRMRSQRAFSIQTPEQYYFCHAAILEH 560

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lar	NP_001260594.1	I-set	36..129	CDD:400151
		Ig strand B	53..57	CDD:409353
		Ig strand C	66..70	CDD:409353
		Ig strand E	93..97	CDD:409353
		Ig strand F	108..113	CDD:409353
		Ig strand G	122..125	CDD:409353
		Ig	141..228	CDD:472250
		Ig strand B	157..161	CDD:409353
		Ig strand C	170..174	CDD:409353
		Ig strand E	192..196	CDD:409353
		Ig strand F	206..211	CDD:409353
		Ig strand G	218..221	CDD:409353
		IgI_3_RPTP_IIa_LAR_like	237..319	CDD:409401
		Ig strand A	237..239	CDD:409401
		Ig strand A'	244..248	CDD:409401
		Ig strand B	251..259	CDD:409401
		Ig strand C	264..270	CDD:409401
		Ig strand C'	272..274	CDD:409401
		Ig strand D	277..281	CDD:409401
		Ig strand E	286..291	CDD:409401
		Ig strand F	298..305	CDD:409401
		Ig strand G	309..318	CDD:409401
		FN3	322..411	CDD:238020
		FN3	<382..747	CDD:442628
		FN3	712..810	CDD:238020
		FN3	832..898	CDD:214495
		FN3	<867..1269	CDD:442628
		fn3	914..998	CDD:394996
		R-PTPc-LAR-1	1498..1735	CDD:350401	11/58 (19%)
		R-PTP-LAR-2	1784..2021	CDD:350402	105/254 (41%)
ptpn9a	XP_005163030.1	CRAL_TRIO_N	11..59	CDD:215024
		SEC14	81..231	CDD:214706	6/31 (19%)
		PTPc-N9	286..554	CDD:350391	108/274 (39%)