DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10366 and si:ch211-79k12.2

DIOPT Version :9

Sequence 1:NP_609995.1 Gene:CG10366 / 35258 FlyBaseID:FBgn0032814 Length:578 Species:Drosophila melanogaster
Sequence 2:NP_001313520.1 Gene:si:ch211-79k12.2 / 568844 ZFINID:ZDB-GENE-131121-535 Length:555 Species:Danio rerio


Alignment Length:503 Identity:119/503 - (23%)
Similarity:183/503 - (36%) Gaps:105/503 - (20%)


- Green bases have known domain annotations that are detailed below.


  Fly   109 QSTPSQERPNLHELRSKFGLLDEETQTEVHYVDKKPKLDEQ-------------LEFLPEESPYE 160
            ||.||::.|..:.:|  ||:..||         ::|:.:|.             |...|..|.::
Zfish    55 QSIPSRQNPVKNAVR--FGVQSEE---------REPRHNESHAHRRTCTCPGCPLSSTPSSSSFQ 108

  Fly   161 LANPLTPEEKQESVDQEQDQPTEEPDEQDADYEPNEDRVLMSLCDVYGIQEDNSSAGSLDGSSPS 225
            ...|     |..|..|.|...:.:........||:...|.:.||...|:..|..:.||...|.|.
Zfish   109 TLKP-----KASSASQIQPPSSTQSTPLQQAKEPSTAPVSLGLCLGLGLSLDEENTGSSSTSRPP 168

  Fly   226 TEKAGEDAADS-----------------EKRHQCNECLRSYATSKTLQRHLRQDHGQ-------- 265
            .:   ||...|                 .:...|..|.|.:.|...|....:....|        
Zfish   169 QQ---EDKGTSTHSPIPQSNPESPGVSPAQAFPCVCCHRGFQTCSQLLSQQKDPESQIAHHYYHH 230

  Fly   266 ----------TEPTTEQLQCPDCPKKFRLHYQLERHMKWHVPLPKRKQYACSSCDKKFATSASAQ 320
                      |..|.....|..|.:.|....||.||.:.|......:|.:|..|:..|...:...
Zfish   231 HHHHCPLSSCTSCTHPSFPCLSCQRTFPTCAQLLRHEQGHAQQDGLQQLSCMHCNASFPRPSQLL 295

  Fly   321 QHEQYMHLDERPRPVICEQCGVGVHSMSALKEHVLKHTDYAPFECEVCKKCFKSANRLKHHKETH 385
            ||::..|. .:....:|.:||...:|.|.|:.|:..||...|:.|..|.|.|..:..||.|:..|
Zfish   296 QHQRTQHA-TKAGGFLCAECGRAFNSHSNLRIHLNVHTGARPYICTNCGKSFSQSGALKIHRRIH 359

  Fly   386 DPHK-YICPECGMQLNSRTTLNRHRLVHTDQMQHKCDYCGREFKRAKALKNHLILHTGLKPYSCD 449
            ...: |.|..||........:..|:.:||.:..:.|..||:.|.::.|||.|..:|||.:|:.|.
Zfish   360 TGERPYTCSYCGRGFPHLAGVRAHQRIHTGEKPYICGQCGKCFTQSGALKIHTRIHTGERPFVCG 424

  Fly   450 FCDRTFANGSNCRTHKKKSH-----PEELAAQEAAGGGRS---------------------HNRN 488
            .|.::|:|.|..|.|.:..|     |..:.....|....|                     ..||
Zfish   425 LCGKSFSNRSGIRFHHRTVHGIVMEPNSVGRPSLAASASSQVSDIQRVQVSAVNQIHFRQIEERN 489

  Fly   489 IPKLEALKAFTKNKDNLSPVATKQS---GCFAFGKKPRPATKDTPASN 533
            :|..|.::   .:|:.||..|.|.:   .|...|::    ..|.|:.|
Zfish   490 LPSKELVQ---PSKEQLSGNADKLALPYACEDCGQR----FPDAPSRN 530

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10366NP_609995.1 zf-AD 28..108 CDD:285071
PTZ00423 131..>230 CDD:240413 23/111 (21%)
COG5048 <222..408 CDD:227381 50/221 (23%)
C2H2 Zn finger 242..263 CDD:275368 5/20 (25%)
C2H2 Zn finger 275..295 CDD:275368 7/19 (37%)
C2H2 Zn finger 306..357 CDD:275368 13/50 (26%)
C2H2 Zn finger 365..385 CDD:275368 7/19 (37%)
C2H2 Zn finger 392..412 CDD:275368 4/19 (21%)
zf-C2H2 418..440 CDD:278523 8/21 (38%)
C2H2 Zn finger 420..440 CDD:275368 8/19 (42%)
zf-H2C2_2 432..457 CDD:290200 11/24 (46%)
C2H2 Zn finger 448..466 CDD:275368 7/17 (41%)
si:ch211-79k12.2NP_001313520.1 C2H2 Zn finger 281..302 CDD:275368 5/20 (25%)
C2H2 Zn finger 311..331 CDD:275368 7/19 (37%)
zf-H2C2_2 323..348 CDD:290200 9/24 (38%)
C2H2 Zn finger 339..359 CDD:275368 7/19 (37%)
zf-H2C2_2 351..374 CDD:290200 8/22 (36%)
C2H2 Zn finger 367..387 CDD:275368 4/19 (21%)
zf-H2C2_2 380..404 CDD:290200 7/23 (30%)
C2H2 Zn finger 395..415 CDD:275368 8/19 (42%)
zf-H2C2_2 407..432 CDD:290200 11/24 (46%)
C2H2 Zn finger 423..442 CDD:275368 7/18 (39%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
00.000

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