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Protein Alignment CG10366 and prdm9

DIOPT Version :9

Sequence 1:	NP_609995.1	Gene:	CG10366 / 35258	FlyBaseID:	FBgn0032814	Length:	578	Species:	Drosophila melanogaster
Sequence 2:	NP_957196.1	Gene:	prdm9 / 393876	ZFINID:	ZDB-GENE-040426-1319	Length:	853	Species:	Danio rerio

Alignment Length:	646	Identity:	137/646 - (21%)
Similarity:	206/646 - (31%)	Gaps:	218/646 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 VEMHAAPAAPHVDRNPSSDWRQWCR------------------LCAKDDVQG------------- 39
            |.:||     ||.|...:::.|:.:                  |.|.|:...
Zfish   243 VYLHA-----HVKRTHPNEYAQFTQTHPLESEAHTPITEVEQCLVASDEALSTQTQPVTESPQEQ 302

  Fly    40 ----NLNVFLKNEDSGEAASMELATAIGKYFWVNITRGEELPETI--CSEC-LSLVTS--LVNFS 95
                |.....:.|:|.|..:.::.||.|           |:.:.|  |.:| .|.:.|  |....
Zfish   303 ISTQNGQPIHQTENSDEPDASDIYTAAG-----------EISDEIHACVDCGRSFLRSCHLKRHQ 356

  Fly    96 ERITRVQKLYCILQ-----------------------STPSQERP-----------------NLH 120
            ..|...:|.||..|                       :..|.:||                 |||
Zfish   357 RTIHSKEKPYCCSQCKKCFSQATGLKRHQHTHQEQEKNIESPDRPSDIYPCTKCTLSFVAKINLH 421

  Fly   121 E----------LR-SKFGLLDEETQ---TEVHYVDKKPKLDEQLEFLPEESPYELANPL------ 165
            :          || .:.|.|..||:   |||.:..:.|..:.     |........|.|
Zfish   422 QHLKRHHHGEYLRLVESGSLTAETEEDHTEVCFDKQDPNYEP-----PSRGRKSTKNSLKGRGCP 481

  Fly   166 -----------TPEEKQESVDQEQDQP--------------------TEEPDEQDADYEPNED-- 197
                       .|:.|...|:.::..|                    ....||.|....|.|.
Zfish   482 KKVAVGRPRGRPPKNKNLEVEVQKISPICTNCEQSFSDLETLKTHQCPRRDDEGDNVEHPQEASQ 546

  Fly   198 -------RVLMSL--------------------CDVYGIQEDNSSAGSLDGSSPSTEKAGEDAAD 235
                   |...:|                    ||:|..:..|            ..:.......
Zfish   547 YICGECIRAFSNLDLLKAHECIQQGEGSYCCPHCDLYFNRMCN------------LRRHERTIHS 599

  Fly   236 SEKRHQCNECLRSYATSKTLQRH-----LRQDHGQTEP--TTEQLQCPDCPKKFRLHYQLERHMK 293
            .||.:.|..||:|:..|..|:||     .|:.|.|:..  |.....|..||..|.....|.:|::
Zfish   600 KEKPYCCTVCLKSFTQSSGLKRHQQSHLRRKSHRQSSALFTAAIFPCAYCPFSFTDERYLYKHIR 664

  Fly   294 WHVP--------------LPKRKQYACSSCDKKFATSASAQQHEQYMHLDERPRPVICEQCGVGV 344
            .|.|              |...|.::||.|.|.|:|....:.|..:   .:..:..:|..||...
Zfish   665 RHHPEMSLKYLSFQEGGVLSVEKPHSCSQCCKSFSTIKGFKNHSCF---KQGEKVYLCPDCGKAF 726

  Fly   345 HSMSALKEHVLKHTDYAPFECEVCKKCFKSANRLKHHKETHDPHK-YICPECGMQLNSRTTLNRH 408
            ...::||:|...||...|:.|..|.|.|..:.:|..|..||...| ::|.:||........|.||
Zfish   727 SWFNSLKQHQRIHTGEKPYTCSQCGKSFVHSGQLNVHLRTHTGEKPFLCSQCGESFRQSGDLRRH 791

  Fly   409 RLVHTDQMQHKCDYCGREFKRAKALKNHLILHTGLKPYSCDFCDRTFANGSNCRTHKKKSH 469
            ...|:.....:|..||:.|.|.::||.|..||.|.|.:.|..|.::|....:...|.:|.|
Zfish   792 EQKHSGVRPCQCPDCGKSFSRPQSLKAHQQLHVGTKLFPCTQCGKSFTRRYHLTRHHQKMH 852

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.