DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10366 and CG7368

DIOPT Version :9

Sequence 1:	NP_609995.1	Gene:	CG10366 / 35258	FlyBaseID:	FBgn0032814	Length:	578	Species:	Drosophila melanogaster
Sequence 2:	NP_001036599.1	Gene:	CG7368 / 39301	FlyBaseID:	FBgn0036179	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	376	Identity:	80/376 - (21%)
Similarity:	135/376 - (35%)	Gaps:	107/376 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    70 ITRGEELPETICSECLSLVTSLVNFS-ERITRVQKLYCILQSTPSQERP-NLHE-LRSKFGLLDE 131
            :|..:||.:.:|:..|.... |.|.| :.:|....:...|...|:...| :||. |:.....:.:
  Fly   159 VTAPQELTQDLCNAILQQQV-LQNTSWQTLTPGTTVADYLSHLPANTLPLSLHHFLKYSAETIKK 222

  Fly   132 ETQTEVHYVDKKPKLDEQLEFLPEESPYELANPLTPEEKQESVDQEQDQPTEEPDEQDADYEPNE 196
            |.|..|..         |::..|......|.....      |:.|:.:|.|.:|.:|..
  Fly   223 ENQQNVVL---------QVQTGPAIGINTLGTTTI------SIPQQAEQLTLQPQQQAT------ 266

  Fly   197 DRVLMSLCDVYGIQEDNSSAGSLDGSSPSTEKAGEDAADSEKRHQCNECLRSYATSKTLQRHLRQ 261
                        :|....:|.:...::.:...||...|.|.|:.:..:      .||..:..||
  Fly   267 ------------LQVQTQAAVTATATTATATTAGGSGATSGKKKKRKK------RSKDRKTKLR- 312

  Fly   262 DHGQTEPTTEQLQCPDCPKKFRLHYQLERHMKWHVPLPKRKQYACSSCDKKFATSASAQQHEQYM 326
                             |.:.||...|:..     ||     |.|..|            |..|
  Fly   313 -----------------PGEIRLGTALDGS-----PL-----YMCPEC------------HVAY- 337

  Fly   327 HLDERPRPVICEQCGVGVHSMSALKEHVLKHTDYAPFECEVCKKCFKSANRLKHHKETHDPHK-Y 390
                 |.|.:             |:.|::.|.....:.|::|:...|..:.|..||::|:|.: |
  Fly   338 -----PEPEL-------------LEVHLVGHNLEKRYVCDICQASLKRKDHLTRHKQSHNPERPY 384

  Fly   391 ICPECGMQLNSRTTLNRHRLVHTDQMQHKCDYCGREFKRAKALKNHLILHT 441
            ||..|......:..|:.|.::|:.:.:|:|..||:.|.|    |:||..||
  Fly   385 ICTVCLKAFKRKEQLSLHFVIHSGEKRHQCGECGKGFYR----KDHLRKHT 431

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10366	NP_609995.1	zf-AD	28..108	CDD:285071	9/38 (24%)
		PTZ00423	131..>230	CDD:240413	14/98 (14%)
		COG5048	<222..408	CDD:227381	38/186 (20%)
		C2H2 Zn finger	242..263	CDD:275368	4/20 (20%)
		C2H2 Zn finger	275..295	CDD:275368	4/19 (21%)
		C2H2 Zn finger	306..357	CDD:275368	8/50 (16%)
		C2H2 Zn finger	365..385	CDD:275368	6/19 (32%)
		C2H2 Zn finger	392..412	CDD:275368	4/19 (21%)
		zf-C2H2	418..440	CDD:278523	9/21 (43%)
		C2H2 Zn finger	420..440	CDD:275368	8/19 (42%)
		zf-H2C2_2	432..457	CDD:290200	5/10 (50%)
		C2H2 Zn finger	448..466	CDD:275368
CG7368	NP_001036599.1	C2H2 Zn finger	330..350	CDD:275368	8/50 (16%)
		COG5048	356..>412	CDD:227381	15/55 (27%)
		C2H2 Zn finger	358..378	CDD:275368	6/19 (32%)
		zf-H2C2_2	370..395	CDD:290200	9/24 (38%)
		C2H2 Zn finger	386..406	CDD:275368	4/19 (21%)
		zf-H2C2_2	399..423	CDD:290200	8/23 (35%)
		zf-C2H2	412..434	CDD:278523	11/24 (46%)
		C2H2 Zn finger	414..434	CDD:275368	10/22 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24403
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100