DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG10366 and ZNF513

DIOPT Version :9

Sequence 1:NP_609995.1 Gene:CG10366 / 35258 FlyBaseID:FBgn0032814 Length:578 Species:Drosophila melanogaster
Sequence 2:NP_653232.3 Gene:ZNF513 / 130557 HGNCID:26498 Length:541 Species:Homo sapiens


Alignment Length:580 Identity:117/580 - (20%)
Similarity:164/580 - (28%) Gaps:219/580 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   140 VDKKPKLDEQLEFLPEESPYELANPLTPEEKQESVDQEQDQPTEEPDEQDADYEPNEDRVLMSLC 204
            ||.:..|||....|..||...|...|..||::|  ::|.|..:::....:.|.|.:.......| 
Human    19 VDTEDSLDEGPGALVLESDLLLGQDLEFEEEEE--EEEGDGNSDQLMGFERDSEGDSLGARPGL- 80

  Fly   205 DVYGIQEDNSSAG-SLDGSSPSTEKA-GEDAADSE------------------------------ 237
             .||:.:|.|..| :|...|...|.| |...|..|                              
Human    81 -PYGLSDDESGGGRALSAESEVEEPARGPGEARGERPGPACQLCGGPTGEGPCCGAGGPGGGPLL 144

  Fly   238 ---------------------KRH----------QCNECLRSYATSKTLQRHLRQDHGQTEPTTE 271
                                 |||          :|..|..:.|....|.||.|...|:     :
Human   145 PPRLLYSCRLCTFVSHYSSHLKRHMQTHSGEKPFRCGRCPYASAQLVNLTRHTRTHTGE-----K 204

  Fly   272 QLQCPDCPKKFRLHYQLERHMKWHV--PLPKRKQYACSSCDKKFATSASAQ---QHEQYMHLDER 331
            ..:||.||........|.||.:.|.  |.|     .|.:|..:..|...|:   ..||...:..|
Human   205 PYRCPHCPFACSSLGNLRRHQRTHAGPPTP-----PCPTCGFRCCTPRPARPPSPTEQEGAVPRR 264

  Fly   332 PRPVI-------------------CEQ--------CGVG-------------------------- 343
            |...:                   |.|        ||.|                          
Human   265 PEDALLLPDLSLHVPPGGASFLPDCGQLRGEGEGLCGTGSEPLPELLFPWTCRGCGQELEEGEGS 329

  Fly   344 ---------------------------------------VHSMSALKEHVLKHTDYAPFECEVCK 369
                                                   .|..:.|..|:..|:...||.|..|.
Human   330 RLGAAMCGRCMRGEAGGGASGGPQGPSDKGFACSLCPFATHYPNHLARHMKTHSGEKPFRCARCP 394

  Fly   370 KCFKSANRLKHHKETHDPHK-YICPECGMQLNSRTTLNRHRLVHTDQMQHKCDYCGREFKRAKAL 433
            ......:.||.|:..|...| |.||.|.....:...|.||..:|:.....:|..|.....::..|
Human   395 YASAHLDNLKRHQRVHTGEKPYKCPLCPYACGNLANLKRHGRIHSGDKPFRCSLCNYSCNQSMNL 459

  Fly   434 KNHLILHTGLKPYSCDFCDRTFANGSNCRTHKKKSHPEELAAQEAAGGGRSHNRNIPKLEALKAF 498
            |.|::.|||.||:.|..|..|..:..|.:.|:|      :.....|||        |.|.|.:.:
Human   460 KRHMLRHTGEKPFRCATCAYTTGHWDNYKRHQK------VHGHGGAGG--------PGLSASEGW 510

  Fly   499 TKNKDNLSPVATKQSGCFAFGKKPRPATKDTPASNPAVIQDAQPEPAPDPGGENATQADT 558
            .                             .|.|.|:|:....| ||....|..|...|:
Human   511 A-----------------------------PPHSPPSVLSSRGP-PALGTAGSRAVHTDS 540

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG10366NP_609995.1 zf-AD 28..108 CDD:285071
PTZ00423 131..>230 CDD:240413 27/91 (30%)
COG5048 <222..408 CDD:227381 58/345 (17%)
C2H2 Zn finger 242..263 CDD:275368 7/20 (35%)
C2H2 Zn finger 275..295 CDD:275368 7/19 (37%)
C2H2 Zn finger 306..357 CDD:275368 16/145 (11%)
C2H2 Zn finger 365..385 CDD:275368 5/19 (26%)
C2H2 Zn finger 392..412 CDD:275368 6/19 (32%)
zf-C2H2 418..440 CDD:278523 5/21 (24%)
C2H2 Zn finger 420..440 CDD:275368 5/19 (26%)
zf-H2C2_2 432..457 CDD:290200 11/24 (46%)
C2H2 Zn finger 448..466 CDD:275368 5/17 (29%)
ZNF513NP_653232.3 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 1..118 30/102 (29%)
C2H2 Zn finger 152..172 CDD:275368 3/19 (16%)
COG5048 176..>228 CDD:227381 15/56 (27%)
C2H2 Zn finger 180..200 CDD:275368 7/19 (37%)
zf-H2C2_2 192..217 CDD:316026 9/29 (31%)
C2H2 Zn finger 208..228 CDD:275368 7/19 (37%)
C2H2 Zn finger 362..382 CDD:275368 3/19 (16%)
COG5048 <372..>450 CDD:227381 21/77 (27%)
C2H2 Zn finger 390..410 CDD:275368 5/19 (26%)
COG5048 414..>487 CDD:227381 22/72 (31%)
C2H2 Zn finger 418..438 CDD:275368 6/19 (32%)
C2H2 Zn finger 446..466 CDD:275368 5/19 (26%)
C2H2 Zn finger 474..493 CDD:275368 6/24 (25%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 492..541 17/93 (18%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR24403
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.100

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