Protein Alignment CG10366 and znf462

DIOPT Version :10

• Sequence 1: NP_609995.1
• Gene: CG10366 / 35258
• FlyBaseID: FBgn0032814
• Length: 578
• Species: Drosophila melanogaster
• Sequence 2: XP_002934034.2
• Gene: znf462 / 100492944
• XenbaseID: XB-GENE-976911
• Length: 2458
• Species: Xenopus tropicalis
• Alignment Length: 550
• Identity: 111/550 - (20%)
• Similarity: 175/550 - (31%)
• Gaps: 191/550 - (34%)

  Fly    81 CSECLSLVTSLV-----------NFSERITRVQKLYCILQSTPSQERPNLHELRSKFG---LLDE 131
            |..|.|.:.|:.           :|.:|..|.::...:|.   .|:...:.|.:.|.|   .|.:
 Frog  1797 CKHCNSKLNSVADLTIHLNAHNEDFQKRAKRQERRKQLLN---KQKLTEIAENKEKMGNEAALHK 1858

  Fly   132 ETQ------------TEVH--------YVDKK------PKLDEQLEFLPEESPYELANPLTPE-E 169
            ..:            .|||        ::.|.      |:|...|    ::..||..:..|.| :
 Frog  1859 SCKEKAVVGYKCKFCVEVHPTLRAICNHLRKHVQYGNVPELSSDL----QDEKYEFTDEDTIEYD 1919

  Fly   170 KQESVDQEQDQPTEE---PDEQDADYEPNE-----------------DRVLMSLCDVYGIQEDNS 214
            ..:.||.|:::..||   |.|::...|..|                 ||||||:   .|::....
 Frog  1920 YDDGVDDEEEEDVEEASTPAEENPVDEAKETKKGRRTRPGGYPCKQCDRVLMSM---QGLRSHER 1981

  Fly   215 SAGSLDGSSPSTEKAGEDAADSEKRHQCNECLRSYATSKTLQRHLRQDHGQTEPTTEQLQCPDCP 279
            |..:|            .....:.::.|..|....|....|.||::..||..:|    .:|..||
 Frog  1982 SHLAL------------AMFTRDDKYSCQFCSFVSAFRHNLDRHVQTHHGHHKP----FRCKLCP 2030

  Fly   280 KKFRLHYQLERH-MKWHVPLPKRKQYACSSCDKKFATSASAQQHEQYMH---------------- 327
            .|...:.:|:.| ||.|.   ....|.||.|.....|.:..:.|...:|
 Frog  2031 FKSSYNSRLKTHIMKAHA---GEHAYKCSFCPFSTMTISQLKDHSLKVHGKTLTLPRIRTISQTS 2092

  Fly   328 --------------LDE-----------------------------RPRPVI------------- 336
                          ||:                             .|.||.
 Frog  2093 PRAKQTTRIGKESGLDDSSYSEPPDVQQQLNHYQSAALARYNNNSPAPLPVSSTSAEQNQEAVLN 2157

  Fly   337 CEQCGVGVHSMSALKEHVL-KHTDYAPFECEVCK--KCFKSANRLKHHKETHD------PHKYIC 392
            ||.|......:.:::.|.. ||.....|:|:.|.  .|||||..: |.:..|.      |....|
 Frog  2158 CEFCDFSSGYIQSIRRHYRDKHGGKKLFKCKDCSFYTCFKSAFTM-HVEAGHSATPMEGPKDLRC 2221

  Fly   393 PECGMQLNSRTTLNRHRLVHTDQ------------MQH------KCDYCGREFKRAKALKNHLIL 439
            |.|......:..:..|.::|.::            .:|      :||.|.......:||:.|:..
 Frog  2222 PLCLYHTKYKHNMIDHIVLHREERVVPIEVCRSKLSKHLQGVVFRCDKCTFTCSSDEALQQHIEK 2286

  Fly   440 HTGLKPYSCDFCDRTFANGSNCRTHKKKSH 469
            |..||||.|..|...........||.::.|
 Frog  2287 HNELKPYKCQLCYYETKLSEELDTHLREEH 2316

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10366	NP_609995.1	zf-AD	28..108	CDD:462262	7/37 (19%)
		COG5048	<222..408	CDD:227381	50/267 (19%)
		C2H2 Zn finger	242..263	CDD:275368	6/20 (30%)
		C2H2 Zn finger	275..295	CDD:275368	8/20 (40%)
		C2H2 Zn finger	306..357	CDD:275368	15/123 (12%)
		C2H2 Zn finger	365..385	CDD:275368	8/21 (38%)
		C2H2 Zn finger	392..412	CDD:275368	4/19 (21%)
		SUF4-like	418..>485	CDD:411020	16/57 (28%)
		C2H2 Zn finger	420..445	CDD:411020	8/24 (33%)
		C2H2 Zn finger	420..440	CDD:275368	6/19 (32%)
		C2H2 Zn finger	448..469	CDD:411020	4/20 (20%)
		C2H2 Zn finger	448..466	CDD:275368	4/17 (24%)
znf462	XP_002934034.2	C2H2 Zn finger	1963..1983	CDD:275370	7/22 (32%)
		C2H2 Zn finger	1997..2017	CDD:275368	6/19 (32%)
		C2H2 Zn finger	2026..2047	CDD:275368	8/20 (40%)
		C2H2 Zn finger	2055..2076	CDD:275368	5/20 (25%)
		C2H2 Zn finger	2221..2241	CDD:275368	4/19 (21%)
		C2H2 Zn finger	2267..2287	CDD:275368	6/19 (32%)