DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PCNA2 and pcna

DIOPT Version :9

Sequence 1:	NP_609994.1	Gene:	PCNA2 / 35257	FlyBaseID:	FBgn0032813	Length:	255	Species:	Drosophila melanogaster
Sequence 2:	NP_571479.2	Gene:	pcna / 30678	ZFINID:	ZDB-GENE-000210-8	Length:	260	Species:	Danio rerio

Alignment Length:	257	Identity:	124/257 - (48%)
Similarity:	190/257 - (73%)	Gaps:	5/257 - (1%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLEARLSQTLLLKKIVDALKEIIAQGTLDCSENGLELQSMDNSHVSLVALSLASDCFEKFHCDRN 65
            |.||||.|..:|||:::|||::|.:...|.|.:|:.|||||:||||||.|:|.||.|:.:.||||
Zfish     1 MFEARLVQGSILKKVLEALKDLITEACWDVSSSGISLQSMDSSHVSLVQLTLRSDGFDSYRCDRN 65

  Fly    66 VSLGLDLKSLGKVLKCANSDDAVTIKAVDRPEKITLSFESDGKERTADYELKLLNLDQDHMEIPK 130
            :::|::|.|:.|:||||.::|.:|::|.|..:.:.|.||:..:|:.:|||:||::||.:.:.||:
Zfish    66 LAMGVNLSSMSKILKCAGNEDIITLRAEDNADALALVFETLNQEKVSDYEMKLMDLDVEQLGIPE 130

  Fly   131 KDYTCFIQLPSSEFARICRDMSMFDESLTIACSSKGIRFLAKGDLGTANIQLSAGTAMD-----V 190
            ::|:|.:::||.||||||||:|...:::.|:|:..|::|.|.|:|||.||:||..:.:|     |
Zfish   131 QEYSCVVKMPSGEFARICRDLSQIGDAVMISCAKDGVKFSASGELGTGNIKLSQTSNVDKEDEAV 195

  Fly   191 SIEVQEPVTQSFAGRYLNTFTKATPLADRVKLYLSDERPLLVEYPIEDYGHIRYYLAPKVND 252
            :||:.|||...||..|||.|||||||:..|.|.:|.:.||:|||.|.|.||::||||||:::
Zfish   196 TIEMNEPVQLIFALNYLNFFTKATPLSKTVTLSMSADIPLVVEYKIADMGHVKYYLAPKIDE 257

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PCNA2	NP_609994.1	pcna	1..254	CDD:273158	124/257 (48%)
pcna	NP_571479.2	pcna	1..258	CDD:273158	124/257 (48%)
pcna	NP_571479.2	PCNA	4..256	CDD:238322	122/251 (49%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170595210
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0592
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62193
OrthoDB	1	1.010	-	-		D1012066at2759
OrthoFinder	1	1.000	-	-		FOG0003572
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100882
Panther	1	1.100	-	-	O	PTHR11352
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X2443
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	12	11.720