Protein Alignment Hakai and Cbll1

DIOPT Version :9

• Sequence 1: NP_001260593.1
• Gene: Hakai / 35256
• FlyBaseID: FBgn0032812
• Length: 473
• Species: Drosophila melanogaster
• Sequence 2: XP_006514999.1
• Gene: Cbll1 / 104836
• MGIID: 2144842
• Length: 502
• Species: Mus musculus
• Alignment Length: 528
• Identity: 136/528 - (25%)
• Similarity: 184/528 - (34%)
• Gaps: 189/528 - (35%)

  Fly    61 ASEDSVMQELDKDGELETPGALEEPLPHGALGAVAASGNMTPATQQPQVLQQVPPPVMSQTTISL 125
            |:.|...|||:.|.||:...:      .|:||.:.....: |.....:...:|.|...:|.|:|.
Mouse     4 ATTDPRDQELELDNELQGTNS------SGSLGGLDVRRRI-PIKLISKQASKVKPAPRTQRTVSR 61

  Fly   126 SLARAV--DMEA-DISQLE------APTFTTLSRGPPEPMLRLKWNHKVSLIGEKVLNPMIHCCD 181
            ..|:|.  |.|. |.::.:      ...|....|.|.    .|.|:.|::::|||...| :|.||
Mouse    62 MPAKAPQGDEEGFDYNEEQRYDCKGGELFGNQRRFPG----HLFWDFKINILGEKDDTP-VHFCD 121

  Fly   182 QCDKPILVYGRMIPCKHVFCLKCA---RAEPIKSCPRCTDKVLRVEQSGLGTVFMCTHGGSRYGS 243
            :|..||.|||||||||||||..||   ..:..|.||.|:|.|.|:||...|::|||:.      .
Mouse   122 KCGLPIKVYGRMIPCKHVFCYDCAILHEKKGDKMCPGCSDPVQRIEQCTRGSLFMCSI------V 180

  Fly   244 SGCRRTYLSQRDLQAHINHRH------------------VAP----------------------- 267
            .||:|||||||||||||||||                  :||
Mouse   181 QGCKRTYLSQRDLQAHINHRHMRAGKPVTRASLENVHPPIAPPPTDIPDRFIMPPDKHHMSHIPP 245

  Fly   268 ------QPPPLQ----------------PQPQLSAMAEQPKMTDLGGVGLGLELHKQRKLSESSV 310
                  .|||||                |..:||.....|:........:....|.    :..:|
Mouse   246 KQHIMMPPPPLQHVPHEHYNQPHEDIRAPPAELSMAPPPPRSVSQETFRISTRKHS----NLITV 306

  Fly   311 PISVSASIASRPVLSRLPLTGGVGNIGSIGSIPPPGSAAAAQNAIHGGHSTLTLANLTRINNANA 375
            ||...:|..:|                   ..|||..|.|..:..:.|...::
Mouse   307 PIQDDSSSGAR-------------------EPPPPAPAPAHHHPEYQGQPVVS------------ 340

  Fly   376 QECHQGKASLHHTL-------------------------KKGTPHQSESVADASYYSS------- 408
               |.     ||.:                         ..||||...|.|.....:|
Mouse   341 ---HP-----HHIMPPQQHYAPPPPPPPPISHPMPHPPQAAGTPHLVYSQAPPPPMTSAPPPITP 397

  Fly   409 ----VLASFGSAAGNPGSGPP---GGGATAAAQPA---NPSG-----------SHSAVGPGALIG 452
                ::|.......:|..|||   .||....|.|.   ||:.           |.....||.:..
Mouse   398 PPGHIIAQMPPYMNHPPPGPPPPQHGGPPVTAPPPHHYNPNSLPQFTEDQGTLSPPFTQPGGMSP 462

  Fly   453 GSTDAPTG 460
            |...||.|
Mouse   463 GIWPAPRG 470

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hakai	NP_001260593.1	RING-HC_HAKAI_like	178..216	CDD:319422	24/40 (60%)
		RING-HC finger (C3HC4-type)	180..216	CDD:319422	23/38 (61%)
Cbll1	XP_006514999.1	RING-HC_HAKAI_like	118..159	CDD:319422	24/40 (60%)
		zf_Hakai	172..203	CDD:375834	23/36 (64%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167834690
Domainoid	1	1.000	50	1.000	Domainoid score	I11644
eggNOG	1	0.900	-	-		E1_KOG2932
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6974
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005494
OrthoInspector	1	1.000	-	-		oto95265
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR13480
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5466
SonicParanoid	1	1.000	-	-		X3911
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.870