DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG10268 and pmvk

DIOPT Version :9

Sequence 1:	NP_609992.1	Gene:	CG10268 / 35255	FlyBaseID:	FBgn0032811	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_001077048.1	Gene:	pmvk / 100003383	ZFINID:	ZDB-GENE-070410-91	Length:	199	Species:	Danio rerio

Alignment Length:	187	Identity:	80/187 - (42%)
Similarity:	125/187 - (66%)	Gaps:	9/187 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 IVLISGKRKCGKDYISERLQRRLGSR-SCIVRISEPIKSEWARKLQLDLDALLGDGPYKEKYRRD 67
            |:|.|||||.||||:::.:|:||.:. .||:|:|.|:|.::|:...||.:.|:|.|.|||.||.|
Zfish     9 ILLFSGKRKSGKDYVTDLIQKRLTAEICCILRLSAPLKEQYAKDHNLDYEELMGSGQYKESYRAD 73

  Fly    68 MIVWSDEVRAQDYGYFCRVAMEEALSRQQTPYILVSDVRRKNDIRWFRETYGPERVITLRLTSRP 132
            ||.|.:..|.:|.|:|||:|::.|..    |..::||.||.:|::||||.: |.:.:.:|:.:..
Zfish    74 MIHWGEMKRQEDSGFFCRLAIKHATQ----PVWIISDCRRMSDVQWFREAF-PNKCVCVRVEASE 133

  Fly   133 ETRSARGWTFTAGIDDVPSECDLDDLADGFDVVLAND--EELDQEAIDILLDRLQLQ 187
            :|||.|||.||:||||..|||.||: ...||.::.||  :::.::.:|.||..::.|
Zfish   134 QTRSERGWRFTSGIDDAESECGLDE-GVKFDRIIRNDGSDDILEKHLDELLSSVRSQ 189

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG10268	NP_609992.1	Pmev_kin_anim	4..188	CDD:130290	80/187 (43%)
pmvk	NP_001077048.1	P-mevalo_kinase	12..121	CDD:282173	51/113 (45%)
pmvk	NP_001077048.1	NK	<94..185	CDD:302627	37/96 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170577735
Domainoid	1	1.000	111	1.000	Domainoid score	I6213
eggNOG	1	0.900	-	-		E1_29ZP3
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4779
Inparanoid	1	1.050	160	1.000	Inparanoid score	I4218
OMA	1	1.010	-	-		QHG52442
OrthoDB	1	1.010	-	-		D1307762at2759
OrthoFinder	1	1.000	-	-		FOG0008115
OrthoInspector	1	1.000	-	-		oto40503
orthoMCL	1	0.900	-	-		OOG6_107244
Panther	1	1.100	-	-	LDO	PTHR13101
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4070
SonicParanoid	1	1.000	-	-		X6067
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	16	15.800