DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment spi and TRADD

DIOPT Version :9

Sequence 1:	NP_001027281.1	Gene:	spi / 35253	FlyBaseID:	FBgn0005672	Length:	234	Species:	Drosophila melanogaster
Sequence 2:	NP_001310481.1	Gene:	TRADD / 8717	HGNCID:	12030	Length:	312	Species:	Homo sapiens

Alignment Length:	54	Identity:	14/54 - (25%)
Similarity:	17/54 - (31%)	Gaps:	9/54 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    49 ALPPTQAPVTSSTTMRTTTTTTPRPNITF---PTYKCPETFDAWYCLNDAHCFA 99
            |..|.|.||.|.:.::......|.....|   |....|      ..|.|...||
Human   176 ASAPLQPPVPSLSEVKPPPPPPPAQTFLFQGQPVVNRP------LSLKDQQTFA 223

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
spi	NP_001027281.1	None
TRADD	NP_001310481.1	TRADD_N	51..160	CDD:401105
		Nuclear export signal. /evidence=ECO:0000250\|UniProtKB:Q3U0V2	147..163
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	170..195		6/18 (33%)
		DD	215..304	CDD:417479	4/9 (44%)
		Interaction with KRT14 and KRT18. /evidence=ECO:0000269\|PubMed:11684708	222..289		2/2 (100%)
		Nuclear localization signal. /evidence=ECO:0000250\|UniProtKB:Q3U0V2	231..244
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S6982
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.950