DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment spi and EREG

DIOPT Version :9

Sequence 1:NP_001027281.1 Gene:spi / 35253 FlyBaseID:FBgn0005672 Length:234 Species:Drosophila melanogaster
Sequence 2:NP_001423.1 Gene:EREG / 2069 HGNCID:3443 Length:169 Species:Homo sapiens


Alignment Length:148 Identity:35/148 - (23%)
Similarity:58/148 - (39%) Gaps:24/148 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    48 TALPPTQAPVTSSTTMRTTTTTTPRPNIT-FPTYKCPETFDAWYCLNDAHCFAVKIADLPVYSCE 111
            |.:.|:..|..||........|...|.:. ....||....:. |||   |...:.:.|:....|.
Human    33 TTVIPSCIPGESSDNCTALVQTEDNPRVAQVSITKCSSDMNG-YCL---HGQCIYLVDMSQNYCR 93

  Fly   112 CAIGFMGQRCEYKEIDNTYLPKRPRPMLEKASIASGAMCALVFML-------FVCLAFYLRFEQR 169
            |.:|:.|.|||:..: ..:.|      |.|..:|...:..::|::       :.| .:|...:.:
Human    94 CEVGYTGVRCEHFFL-TVHQP------LSKEYVALTVILIILFLITVVGSTYYFC-RWYRNRKSK 150

  Fly   170 AAKKAYEL----EQELQQ 183
            ..||.||.    :.||.|
Human   151 EPKKEYERVTSGDPELPQ 168

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
spiNP_001027281.1 None
EREGNP_001423.1 PHA02887 <64..148 CDD:333467 21/95 (22%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 1 0.900 - - OOG6_117627
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
10.900

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