DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tep4 and AI182371

DIOPT Version :9

Sequence 1:	NP_001260590.1	Gene:	Tep4 / 35248	FlyBaseID:	FBgn0041180	Length:	1498	Species:	Drosophila melanogaster
Sequence 2:	XP_017174840.1	Gene:	AI182371 / 98870	MGIID:	2138853	Length:	366	Species:	Mus musculus

Alignment Length:	271	Identity:	59/271 - (21%)
Similarity:	101/271 - (37%)	Gaps:	51/271 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 RADAFAVSLCVILALLQTMEPVKAEGKYTIVGPGTIHSHRDYNVAVAVHQTKEPVTLKVGITG-P 66
            :|..|..:|..::.|.|:..  :.:.:|.|..|.........||.|..|...|.....|.:.. |
Mouse    17 QAMGFWGTLLFLIFLEQSWG--QEQTRYIISTPIVFRVGAPENVTVQAHGHTEAFDTTVSVKSYP 79

  Fly    67 SYN---KTETVELATAGEFKQ---ITFKLPPLEAGEYNLTAEGVKGLEFKNSTKLN-----WENF 120
            ..|   ...||.|:...:|:.   :|.:...|..|: |..:.....:..|:..||.     ::|.
Mouse    80 DENVRYSFSTVNLSPENKFQNTAILTIQAKQLSEGQ-NSFSNSYLEVVSKHFAKLEIVPIIYDND 143

  Fly   121 KPYIKIQTDKGKYKPGDTINYRVIFLDENLRPDTAKDEVVVWFEDSKRNRIKQEKHIKTTGGVYT 185
            ..:  :||||..|.|...:..||..::::|.|.|.  |.|:.|.|.:.:::...:....||....
Mouse   144 SLF--VQTDKSVYTPQQPVKVRVYSVNDDLEPATR--ETVLTFIDPEGSQVDTIEGNNLTGIASF 204

  Fly   186 GKFELSEFATLGSWSLHVQ-NGDQHHDGGIYFGGRKQFGGFGHRWHRSDELVNFEVEKYVLPKYS 249
            ..||:......|.|::..: ..|....|..|                      |||::|
Mouse   205 PDFEIPSNPKHGRWTVKAKYREDASKTGTTY----------------------FEVKEY------ 241

  Fly   250 VKMDATQQVSV 260
               |.|.::|:
Mouse   242 ---DKTYRISI 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tep4	NP_001260590.1	A2M_N	126..219	CDD:280081	24/93 (26%)
		A2M_N_2	528..653	CDD:285005
		A2M	768..859	CDD:278630
		A2M_2	982..1279	CDD:239227
		A2M_comp	1035..1281	CDD:284982
		A2M_recep	1389..1479	CDD:284981
AI182371	XP_017174840.1	MG1	42..138	CDD:375333	22/96 (23%)
		A2M_N	145..238	CDD:376626	25/118 (21%)
		ANATO	279..347	CDD:237984
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167839998
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2373
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.740