Protein Alignment Tep4 and LOC108645185

DIOPT Version :10

• Sequence 1: NP_001260590.1
• Gene: Tep4 / 35248
• FlyBaseID: FBgn0041180
• Length: 1498
• Species: Drosophila melanogaster
• Sequence 2: XP_031761601.1
• Gene: LOC108645185 / 108645185
• XenbaseID: XB-GENE-29090367
• Length: 1449
• Species: Xenopus tropicalis
• Alignment Length: 1620
• Identity: 394/1620 - (24%)
• Similarity: 650/1620 - (40%)
• Gaps: 336/1620 - (20%)

  Fly    10 SLCVILALLQTMEPVKAEGKYTIVGPGTI---HSHRDYNVAVAVHQTKEPVTLKVGITGPSYNKT 71
            :|.:.||||.....::|:..|.::.|..:   ||.:     ..||.:......::.:|.....:.
 Frog     6 ALGLALALLHLSGTLEAKLHYAVIFPSELVAPHSEQ-----ACVHLSGAEGDSRIQVTLNMAERN 65

  Fly    72 ETV---ELATAGEFKQITFKLPPLEAGEYNLTAEGV----KGLEFKNSTKLNWENFKPYIKIQTD 129
            .||   .|.....|..:||::||...|...:....:    .|....||:|:..:..:....||||
 Frog    66 STVIERNLRQKSLFSCVTFQVPPPTQGNEEVATMEILIESAGETVTNSSKVLVKRRRTSTFIQTD 130

  Fly   130 KGKYKPGDTINYRVIFLDENLRPDTAKDEVVVWFEDSKRNRIKQEKHIKTTGGVYTGKFELSEFA 194
            |..||||||:..||:.|:|||:....:..|.. .:|.:.|.|.|..::..|.|:......||...
 Frog   131 KAVYKPGDTVQIRVVNLEENLQLKETQVSVCS-LQDPRWNHITQWLNVTVTQGIAELSLPLSPEP 194

  Fly   195 TLGSWSLHVQNGDQHHDGGIYFGGRKQFGGFGHRWHRSDELVNFEVEKYVLPKYSVKMDATQQVS 259
            ..|.:::.|                      ||..|      .|.|..|.|||:.|.....:.|.
 Frog   195 LFGQYAIRV----------------------GHTVH------FFNVAGYALPKFEVVFQFPKAVL 231

  Fly   260 VRDGEFNVVLKANYTYGKPVNGKVLVNV-----------HLDSTSS-WENVDGKTVQTDYPGHSV 312
            ....:|.:.:...|.||:||.|.....|           |..:.|. ..:..||..|:   |.|:
 Frog   232 SNSEQFQLKICGRYPYGQPVQGTYQATVCRWAFLVYWSGHFQNFSDLCVDFSGKLEQS---GCSI 293

  Fly   313 VGTADMVGGKAKLTMDLKDFASYLPHKTSSSYAQITATVEEDFTGVKLNETGGVQL--------- 368
                          :.:|.....:.:.|...|.:..||:.|:.||:|.:...|..:
 Frog   294 --------------LQIKSDTFRIAYNTHEMYLEGVATITEEGTGMKYSGRDGTTILSTLKSCRF 344

  Fly   369 ----------YPYRYEMSCTDYSSCFSFKPDKEHELNFKITYVDGSLITDTKSVVKAKFTEGIRR 423
                      .|||..:...|.:.  ...|:::..|......:..:|::|...:|
 Frog   345 LDADSNYKPGIPYRGTIKVMDGND--DPLPNQKVSLTINPMNITENLVSDENGLV---------- 397

  Fly   424 NYAFYAFGTDHQEPELPTIEKKTFVFESHLNASGVAPFKVVLPDLPDIANFTRYYSIELEFVDEK 488
                 :|..|:           |..:|.          |:.|...|::.|...:||..:..|..|
 Frog   398 -----SFQLDN-----------TTAWEG----------KLRLTASPEMENTVDWYSGLIIPVLGK 436

  Fly   489 RDLYTTYPYREPK----QIENPSSE---EEKEWFRAEVQRPKDVWNLKIGQE-------YQVI-- 537
            ..|..| |:..|.    ::.:...|   |.:...|.|...|    |..:|.|       |.|:
 Frog   437 DSLELT-PFESPSKSFLKLHSQQGELPCEGQRDVRVEYIIP----NSALGMEAKHMELHYLVVSK 496

  Fly   538 --LNSSRPLKYFVYNIVG----RGNILETKRVDLAEPQTTVNVTIKPT-----FLTTPYGRVYFY 591
              :..|..::..:.:.||    ||.:.....:.|     |::..:.||     |::.|
 Frog   497 ESIKDSGSVEVPITSEVGGSSVRGEVRGEVSIKL-----TLSADVSPTLRALAFISLP------- 549

  Fly   592 YVDETGEFRYTEETFSVEVELQNQIEIK-APAEVKPGADVALEIKTSPKSFVGLLAVDQSVLLLG 655
                .||......||.::...:|::.:. :|.||.|||||:|:::.:..|..||..||::|   .
 Frog   550 ----NGELVADSATFKLQRCFKNKVSVGFSPDEVLPGADVSLQVQAAAGSLCGLRVVDKTV---E 607

  Fly   656 SNNDLNKE-----------SFNWRLNGYDTSTPWQ-----GGYSYYPGERTGVVTMTNAY----- 699
            ...|:..:           ::::|:...|.:.|..     ..||.:...|..:|  ||||
 Frog   608 PEVDVTADRIEKLFPYFTGTYDYRIKDADVNCPLNQKYRVDVYSLFKDMRLKIV--TNAYNKRPS 670

  Fly   700 ---------FFYNRTAPDYN---ILTEGFGGSSFAMRKTTVAHDSHVFHSGAGGPT----QAVGF 748
                     ..|..|....:   .|.:.||.:.    ..||...:|:      .||    :...|
 Frog   671 GCWEKDVEEMLYVPTEIQLSYLKALAQLFGVNP----DWTVELPTHI------EPTPKFRRVEDF 725

  Fly   749 SAESAS----------ASAAPVVRKNFAETWIF---ADIESTEEEVFKWVKTIPDTITNWVVTGF 800
            |..|.|          ..||.::..:..||||:   |..||...||.   .:.|||||.|....|
 Frog   726 SVISMSNDFRDKNEITKGAAEIIPVSLPETWIWELAAVGESGRAEVH---GSAPDTITEWNAGAF 787

  Fly   801 SLHPQKGLGVTNDQTNIKTFQPFFVSVRLPYSVKRGEVINVPALVFNYLPKTLDVE-LTLDNEDQ 864
            .:.| .|.|: :..|:::.||||||.:.|||||.|||...:.|.|||||...:.|: :.|.:::.
 Frog   788 CMGP-SGFGI-SPPTSLRAFQPFFVELTLPYSVVRGESFTLKASVFNYLKHCIKVQTILLPSQEL 850

  Fly   865 EYD-FVDA--SNEVIGDQKRTQNIRVGANEAAGASFLIRPKVIG--NILLKFKAISPLAG--DAI 922
            |.: ..|.  |:.:..::.:|....:.|:.....:..:|.:.:.  ::......|.|..|  |.:
 Frog   851 ELEPCADCQYSSCLCAEESKTFYWNLKASNLGEVNVTVRTEALNTQDMCNNEIPIVPKQGHSDTV 915

  Fly   923 HKPLKVVPEGITQYQNRAFFI---NLKDTGEFKNTFELEVPEDVVPDSERVEFGLVGDLLGPVVK 984
            .|||.|.|.||...::....|   |.|...: |....|:|||:|:..|||....::|||:|..::
 Frog   916 IKPLLVQPGGILVEKSHNSLICRQNAKAHSK-KEKISLKVPENVLKGSERAYITVLGDLMGTAMQ 979

  Fly   985 NLENLLRLPSGCGEQTMSKLVPNYLVRDYLKSIKKLTPALDTRIKRNLQDGYQHMLHYRHDDGSF 1049
            ||:.||.:|.|..||.|....|:..:..||::..:|:|.:.::.||.|.||||..|.|:..|..:
 Frog   980 NLDWLLPMPFGNAEQKMILFAPSIYILQYLENTLQLSPEIQSKAKRLLTDGYQRQLPYKVYDRYY 1044

  Fly  1050 SSFGPTKWRQEDPVRNGSTWLTAYVL-------RSFSKIKDIIDLDEQILAKGYEFLLTRQAENG 1107
            ..|..........:.|.|   .|::.       |:...::|    ||
 Frog  1045 YLFRSQSQENSWSIENSS---MAHLCSPAILYNRNIGGVED----DE------------------ 1084

  Fly  1108 SFTEHGEYFYSSQRSLLTLTANSLLALLEEEKPNQAAIDKAVAYLSANTAESIE------LLPKS 1166
                            |:|:|...:||::...|....|.:...|.....|:::.      ||..:
 Frog  1085 ----------------LSLSAYVTVALMDAGMPQTDTILRHALYCLREAAKNVSSAYTQALLAYT 1133

  Fly  1167 IAIYALQKAKAPEAAKQVASLKSLAKHEDDRTWWTEDLDKLRASKNCGRWWCWIWSQDVEITSYA 1231
            .::....|.:....||    |:..|..:|.:..| |.:....|.....  |....|.:||:.||.
 Frog  1134 FSLSGDNKFREMLLAK----LEEKAIRKDGQLHW-EQIPAFEAFNLSS--WHRAPSAEVELASYV 1191

  Fly  1232 LLSL---LDSDQETADSVLNTVRWLIAQRNGFGGFASSQDTVVGLTALIKFAEKSGYEAAKWEVT 1293
            ||:|   ...||..|..::|   ||..|:|.:|||.|:|||||.|.||.::||.:..:  |.:||
 Frog  1192 LLALRSETKKDQRKASEIVN---WLSKQQNPYGGFYSTQDTVVALQALAEYAEATFSD--KGDVT 1251

  Fly  1294 VSNKGKREKTEKLNTSEENDLLLQTVEFPQGTKSLEFEAKGTGAAMVQISYQYNLVEKEPKPSFK 1358
            |:...|....::.:..:.|.||||....|.........|.|:|...||...:||:.......:|.
 Frog  1252 VTVTSKTGFHQQFHVDQTNRLLLQKASLPDIPGEYSLSATGSGCVYVQTVLRYNIPPPRSDATFS 1316

  Fly  1359 IQTTVLPESSPANLELSVCVD-YVE-EGESKESNMAILEVSLPSGYTADEDSFADIRNIERVRLV 1421
            ::....|:..|......:.:| |:: .|..:|||:|::||.:.||:.....:...:.:...::.:
 Frog  1317 VRVETQPKQCPQEPMKQMGIDIYIQYTGSREESNLALVEVKMLSGFIPAWSTTHQLVSSNTIKHI 1381

  Fly  1422 ETKNGDSVVVIYFENLAKNEEKCIRIEAYRTHAVANQKPSSVVLYDYYD-TNKKATEYYS 1480
            ||:|  .|:.:|...|. ::...:.....:...|.|.||::|.:||||: |....|||.|
 Frog  1382 ETQN--DVLALYLNELG-HDPVHLSFMVEQDIVVKNLKPATVKVYDYYEPTEHAVTEYNS 1438

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep4	NP_001260590.1	YfaS	<76..1411	CDD:441940	359/1476 (24%)
		A2M_2	982..1279	CDD:239227	81/312 (26%)
		A2M_recep	1387..1480	CDD:462226	27/93 (29%)
LOC108645185	XP_031761601.1	YfaS	<126..1435	CDD:441940	364/1490 (24%)
		ISOPREN_C2_like	977..1239	CDD:415487	81/312 (26%)