Protein Alignment Tep4 and LOC108644844

DIOPT Version :9

• Sequence 1: NP_001260590.1
• Gene: Tep4 / 35248
• FlyBaseID: FBgn0041180
• Length: 1498
• Species: Drosophila melanogaster
• Sequence 2: XP_031761243.1
• Gene: LOC108644844 / 108644844
• -ID: -
• Length: 1468
• Species: Xenopus tropicalis
• Alignment Length: 1625
• Identity: 385/1625 - (23%)
• Similarity: 641/1625 - (39%)
• Gaps: 355/1625 - (21%)

  Fly    30 YTIVGPGTIHSHRDYNVAVAVHQTKEPVTLKVGITGPSYNKTETV---ELATAGEFKQITFKLPP 91
            |.::.|..:|........|.|...:|.:||..  |..:..:..|:   .|..|.:.:..:|:.||
 Frog    23 YILLAPAEVHYPSTERACVHVSGARENLTLTT--TLQTEGRDTTLYQHHLTEATQIQCFSFQTPP 85

  Fly    92 LEAGEYNLTAEGV----KGLEFKNSTKLNWENFKPYIKIQTDKGKYKPGDTINYRVIFLDENLRP 152
            ...|...:....:    |..|...|.::...:......|||.:..||||.|:.:.::..|...|.
 Frog    86 PAGGTEEVATIHISLMGKTTEITESKQILIRSVAVSTIIQTSQPIYKPGQTVKFGILSFDREFRA 150

  Fly   153 DTAKDEVVVWFEDSKRNRIKQEKHIKTTGGVYTGKFELSEFATLGSWSLHVQNGDQHHDGGIYFG 217
            ...|...|. .:|...|:|.|..::....|.....|.|:..|..|::|:|..||.|
 Frog   151 VNDKCPFVE-LKDPNGNQIGQWSNLTPHQGFIDLSFSLAPEAAQGTYSIHTPNGHQ--------- 205

  Fly   218 GRKQFGGFGHRWHRSDELVNFEVEKYVLPKYSVKMDATQQVSVRDGEFNVVLKANYTYGKPVNGK 282
                               .|.|.::.:||:.|.:.....|::.|..|.:.:...:|:||||.|.
 Frog   206 -------------------KFHVLEFTIPKFEVFVLLPSVVTLLDKAFQLKVCGRHTFGKPVQGN 251

  Fly   283 VLVNV--------------------------HLDSTSSWENVDGKTVQTDYPGHSVVGTADMVGG 321
            :.|.:                          ..:...:||      :.||
 Frog   252 ISVRLCRRVVKYYWGPYPRPQDICTVYNGQTEKNGCRTWE------ILTD--------------- 295

  Fly   322 KAKLTMDLKDFASYLPHKTSSSYAQITATVEEDFTGVKLNETGGVQLYPYRYEMSCTDYSSCFSF 386
                :..|:.: :|..:..:|::     .|..: |||::|.||                 ||
 Frog   296 ----SFQLRSY-NYQANFEASAF-----LVGRE-TGVQINGTG-----------------SC--- 329

  Fly   387 KPDKEHELNFKITYVDGSLITDTKSVVKAKFTEGIRRNYAFYAFGTDHQEPELPTIEKKTFVFES 451
               :...:..|:| :|||.|::      :.:..|:|........|.|.:    |...|..::.|.
 Frog   330 ---RISAMIAKVT-IDGSEISE------SYYKTGLRYRGTMRLEGADGK----PMKSKTLYLVEE 380

  Fly   452 HLNASGVAPFKVVLPDLPDIANFT---------------RYYSIELEFVDEKRDLYTTYPYREPK 501
            :.:.|...|::.   |....|.||               ||....:|||..:.:.|    |::..
 Frog   381 YDSESRERPYET---DESGQAPFTLDTRLWNGNTVWLSARYQKENMEFVYGELNPY----YQDAH 438

  Fly   502 QIENPSSEEEKEWFRAEVQRPKDVWNLKIGQEYQVILN------------SSRPLKYFVYNIVGR 554
            |...|.|.....:.:.:   |.| ..|...|:|.:.::            :|..|.|.|   :.:
 Frog   439 QTLQPFSAITNSFLKVQ---PVD-HTLLCDQQYPIEIDYLIRGSELGREQNSLELHYVV---MAK 496

  Fly   555 GNILETKRVDL-AEPQTTVNVTIKPTFLTT----PYGRVYFYYVDETGEFRYTEETFSVEVELQN 614
            |.:....:::| ....:.:..||:...|.|    |..::..|.:...|......|.|.|:...:|
 Frog   497 GELALNGKLELNVSRDSVLTGTIELPLLVTADIAPKAQILVYAILANGWVAGDTEEFRVDKCFKN 561

  Fly   615 QIEIK-APAEVKPGADVALEIKTSPKSFVGLLAVDQSVLLLGSNNDL------------NKESFN 666
            ::... :..|..||::|:|.::.||.|...|..||:.::.|....:|            |:..:.
 Frog   562 KVTAGFSDYEKTPGSNVSLHLQASPGSLCSLRVVDEGIISLRPEAELSSDLLYSFVSVRNQYGYP 626

  Fly   667 WR-------------------LNGYDTS---TPWQGGYS---YYPGERTGVVTMTNAY------- 699
            :|                   |||::..   ..|:...|   :...:|.|:..:||..
 Frog   627 YRVREDDPICWSPSPRFSKRSLNGHERQKRHINWRTPRSLDMFKLIKRMGLKILTNTIVKKPKEC 691

  Fly   700 FFYNRTA--PDYNILTEGFGGSSFAMRKTTVAHDSHVFHSGAGGPTQAVGFSAESASASAAPVVR 762
            ..|...|  ..|::..:.|....    ...|..|..|...|...||          .......:|
 Frog   692 HVYPPVAALSRYDLSVDLFNPPP----SPPVMVDDLVDILGQSSPT----------LTEVKEKIR 742

  Fly   763 KNFAETWIFADIESTEEEVFKWVKTIPDTITNWVV-------TGFSLHPQKGLGVTNDQTNIKTF 820
            |:|.||||:..|.............:|||||.|..       ||..|.|         ...::.|
 Frog   743 KDFPETWIWHFIPLGNSGQASMELKVPDTITEWKAKMLCMGDTGLGLSP---------TATLRAF 798

  Fly   821 QPFFVSVRLPYSVKRGEVINVPALVFNYLPKTLDVELTLDNEDQEYDFVDASNEVIGDQKRTQNI 885
            ||||:.:.|||||.|||...|.|.|||::.:||.|..||                    |.:..:
 Frog   799 QPFFIYMTLPYSVVRGESFPVKASVFNFMNRTLMVTSTL--------------------KESPKL 843

  Fly   886 RVGANEAAGASFLIRP---KV---------IGNILLKFKA----ISPLAG------------DAI 922
            ::....|...:..:.|   ||         :|:..::.:|    ...|.|            |.:
 Frog   844 KLTGCPACLYTQCVAPGETKVFVWEATALGLGSAQVEVRAEAIPTGELCGGEVPTVPEDGALDIL 908

  Fly   923 HKPLKVVPEG--ITQYQNRAFFINLKDTGEFKNTFELEVPEDVVPDSERVEFGLVGDLLGPVVKN 985
            .:||::.|||  :.:.||   |:...:.........:.:|.|:||||.|.|..:||||:|..::|
 Frog   909 IRPLEIKPEGMPVEKCQN---FLLCAEENLSSQAVSISLPPDMVPDSARAEISIVGDLMGKPLEN 970

  Fly   986 LENLLRLPSGCGEQTMSKLVPNYLVRDYLKSIKKLTPALDTRIKRNLQDGYQHMLHYRHDDGSFS 1050
            :||||.||:|||||.|:|...|..|..||::..:||..:..|.:.....|||..|:|:..|||||
 Frog   971 VENLLDLPTGCGEQNMAKFASNLYVLRYLENTNQLTDTVRVRGEVYQAHGYQQELNYKRLDGSFS 1035

  Fly  1051 SFGPTKWRQEDPVRNGSTWLTAYVLRSFSKIKDIIDLDEQILAKGYEFLLTRQAENGSFTEHGEY 1115
            :||     ::|  ..|:|||||:|::.|..:...|.:||:.|.:...:|.:.|..:|.|...|..
 Frog  1036 AFG-----EKD--EEGNTWLTAFVMQIFYAVSHFISVDEKHLYEAIAWLKSNQLPSGCFIRRGTL 1093

  Fly  1116 FYSSQRSLL----TLTANSLLALL-----EEEKPNQAAIDKAVAYLSANTAESIELLPKSIAIYA 1171
            |.||.:..:    ||||....|:|     ||::    .:.||:..|..:       ||...:.||
 Frog  1094 FKSSLQGGVNDETTLTAYVAAAILQIKWTEEDE----MLQKALQCLQNS-------LPNVTSTYA 1147

  Fly  1172 L-------QKAKAPEAAKQ-VASLKSLAKHEDDRTWWTEDLDKLRASKNCGRWWCWIWSQDVEIT 1228
            :       ..||..|.... :.||...|...||:.:|..:.::...:|...  |....|..||..
 Frog  1148 MALLSFTFTLAKNFELRNSLLRSLYEKATITDDQVYWLLNPNQAPPTKTSP--WAQPNSLQVEAA 1210

  Fly  1229 SYALLSLLDSDQETADSVLNTVR---WLIAQRNGFGGFASSQDTVVGLTALIKFAEKSGYEAAKW 1290
            ||.:||.|..:..|.:.:.|..:   ||..|:|..|.|.|:|||||...||.::||.|.......
 Frog  1211 SYVILSHLSLENPTKNDICNASKIASWLRQQQNPHGSFGSTQDTVVAFHALSRYAEISYTGHLGL 1275

  Fly  1291 EVTVSNKGKREKTEKLNTSEENDLLLQTVEFPQGTKSLEFEAKGTGAAMVQISYQYNLVEKEPKP 1355
            ||||....:.....:.....:...|||.....:...:.....||.|...:|:..:||.......|
 Frog  1276 EVTVELAEEGGAKHQFWVDNKTRFLLQKTRLDKVPGNYTTRVKGEGCVNLQVILKYNTKPAGKSP 1340

  Fly  1356 SFKIQTTVLPES----SPANLELSVCVDYVEEGESKESNMAILEVSLPSGYTADEDSFADIRNIE 1416
            :|:::.....:|    |.:...|::||.|.  |:.:::||.:::..|.||:::..::..::.|..
 Frog  1341 AFELRLRSSEDSCRNQSVSCYNLTICVQYT--GQRQKTNMVLIQADLLSGFSSIPETINELENHH 1403

  Fly  1417 RVRLVETKNGDSVVVIYFENLAKNEEKCIRIEAYRTHAVANQKPSSVVLYDYYDTNKKATEYYSI 1481
            .|:.:|.|...  :|||.:.|: :|.:|....|.:...|.|.....|.:||:|...::....|::
 Frog  1404 LVKKIEIKMDQ--IVIYIDELS-HETQCFSFLARQDVLVENLASQLVKVYDFYQREEEVDAMYNL 1465

  Fly  1482  1481
             Frog  1466  1465

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep4	NP_001260590.1	A2M_N	126..219	CDD:280081	26/92 (28%)
		A2M_N_2	528..653	CDD:285005	31/142 (22%)
		A2M	768..859	CDD:278630	35/97 (36%)
		A2M_2	982..1279	CDD:239227	104/316 (33%)
		A2M_comp	1035..1281	CDD:284982	83/265 (31%)
		A2M_recep	1389..1479	CDD:284981	22/89 (25%)
LOC108644844	XP_031761243.1	A2M_N	124..198	CDD:396416	21/74 (28%)
		MG3	211..301	CDD:407663	18/114 (16%)
		MG4	348..438	CDD:407661	20/100 (20%)
		A2M_N_2	452..602	CDD:400170	33/156 (21%)
		A2M	748..837	CDD:395153	35/97 (36%)
		A2M_2	968..1264	CDD:239227	104/315 (33%)
		A2M_recep	1376..1463	CDD:400149	22/89 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	47	1.000	Domainoid score	I11799
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm9328
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000