Protein Alignment Tep4 and LOC103909927

DIOPT Version :9

• Sequence 1: NP_001260590.1
• Gene: Tep4 / 35248
• FlyBaseID: FBgn0041180
• Length: 1498
• Species: Drosophila melanogaster
• Sequence 2: XP_009296557.2
• Gene: LOC103909927 / 103909927
• -ID: -
• Length: 1453
• Species: Danio rerio
• Alignment Length: 1608
• Identity: 429/1608 - (26%)
• Similarity: 663/1608 - (41%)
• Gaps: 333/1608 - (20%)

  Fly    22 EPVKAEGK------YTIVGPGTIHSHRDYNVAVAVHQTKEPVTLKVGITGPSYNKTETVELATAG 80
            |||....:      :.:..|..|.|.....:..::.:.:..:|:.:.:......:|:.....|..
Zfish    33 EPVVTADEQISGPLFLVTFPSLIESGSGAKLCASLLKPQGSLTITITLVDDKNTETQLARQTTQR 97

  Fly    81 EFKQ-ITFKLPPLEAGEYNLTAEGVKGLEFK--NSTKLNWENFKPYIKIQTDKGKYKPGDTINYR 142
            :..: ..|:.|.:...........|:|..||  ...|:.:.::.|...|||||..|.||.|:|:|
Zfish    98 KLHRCFNFQAPLVNGDSVQTVRVVVQGQSFKMTEERKVMFRSYLPLTFIQTDKPLYNPGQTVNFR 162

  Fly   143 VIFLDENLRPDTAKDEVVVWFEDSKRNRIKQEKHIKTTGGVYTGKFELSEFATLGSWSLHVQNGD 207
            |:.:.:.|.|......:|| .||.:..||.|..::.:...:......|...|.:|.::|..
Zfish   163 VVTMSDKLVPLDQMYNLVV-LEDFRNIRINQWTNVSSVNWILELSHVLIPEAQVGMYTLRA---- 222

  Fly   208 QHHDGGIYFGGRKQFGGFGHRWHRSDELV--NFEVEKYVLPKYSVKMDATQQVSVRDGEFNVVLK 270
                   |.|               |.::  :|:|::|||||:.|.::|.|..||.|....|...
Zfish   223 -------YIG---------------DRIISQSFDVKQYVLPKFDVTVNAPQTYSVADVGLKVEAC 265

  Fly   271 ANYTYGKPVNGKVLVNVHLDS---------TSSWENVDGKTVQTDYPGHSVVGTADMVGGKAKLT 326
            ..||:|:||.|:|||.|....         ||...|...||..|               |.|.||
Zfish   266 GKYTFGQPVPGQVLVQVCRQPLTYVQDPKVTSICLNKSTKTNNT---------------GCASLT 315

  Fly   327 MDLKDF--ASYLPHKTSSSYAQITATVEEDFTGVKLNETGGVQLYPYRYEMSCTDYSSCFSFKPD 389
            :....|  .|:..:..:|....:..|  |:.|||.::::..|.:   .:|:.
Zfish   316 LSTSSFFGTSFESNLQNSFVVNVNLT--EEGTGVVMSKSTTVSI---TFEVG------------- 362

  Fly   390 KEHELNFKITYVD-------GSLITDTKSVVKAKFTEGIRRNYAFYAFGTDHQEPELPTIEKKTF 447
                   |:|:||       ||.:....||  :.|......:.|.|...:.....:|
Zfish   363 -------KVTFVDLPKFYNYGSTLNGKISV--SDFNGNPINSKAVYVLDSSTWPNKL-------- 410

  Fly   448 VFESHLNASGVAPFKV---VLP--DLPDIANFT--RYYSIELEFVDEKRDLYTTYPYREPKQIEN 505
            :|....|.:|:|.|.:   ..|  ||..:|:.|  .|:|....:......|...:....|   :|
Zfish   411 LFNLTTNKNGLAMFSLDTTAFPQADLNLVASATPQSYFSYNSPYFTTDTRLVQLFQTAAP---DN 472

  Fly   506 PSSEEEKEWFRAEVQRPKDVWNLKIGQEYQVILNSSRPLKY------------FVYNIVGRGNIL 558
            ||..:..   ...:::|     ||.|..|.|      .:||            .:|.::.||.|:
Zfish   473 PSFSDLS---IVTLEQP-----LKCGSTYAV------TVKYSFVGETGDYSADIIYMVMSRGVII 523

  Fly   559 ----ETKRVDLAEPQTTVNVTIKPTFLT--TPYGRVYFYYV--DET---GEFRY-TEETFSVEVE 611
                :|.:....:..|:..|:...:.|.  .|..::..:.|  .:|   |...: ||:.||.:|.
Zfish   524 LHGFKTVQALAFDTITSGTVSFDLSILANMAPMVQILAFCVLPSQTVVAGSASFDTEKCFSNQVS 588

  Fly   612 LQNQIEIKAPAEVKPGADVALEIKTSPKSFVGLLAVDQSVLLLGSNNDLNKESFNWRLNGYDTST 676
            ||     .:||...||....|.:.....|..||.|:|||||:|.|...|..|:....|
Zfish   589 LQ-----FSPASAVPGEGSVLTVSAQAGSLCGLSAIDQSVLILQSGGRLTAEAVFGLL------- 641

  Fly   677 PWQGGYSYYPG-------------------------ERTGVVTMTN------AYFFYNRTAPDYN 710
            |.|..|.|.||                         :..|:...||      ....|.|    .|
Zfish   642 PVQSLYDYPPGVEDQQDCLQVRPRRAVPTDQAYNTFKGVGIKMATNLPVREPECLTYRR----LN 702

  Fly   711 ILTEGFGGSSFAMRKTTVAHDSHVFHSGAGGPTQAVGFSAESASASAAPV-VRKNFAETWIF--- 771
            ......|...|||.|...|             ..||...|.|.|.|...| :|..|.||||:
Zfish   703 FYRNFRGPMLFAMDKVLAA-------------PAAVSEIAGSPSGSPVDVTIRTFFPETWIWQLT 754

  Fly   772 --ADIESTEEEVFKWVKTIPDTITNWVVTGFSLHPQKGLGVTNDQTNIKTFQPFFVSVRLPYSVK 834
              .|..||...:     |:|||||.|....|.| ...|.|:. ....:..|||||:.:.||||:.
Zfish   755 PVGDSGSTSVPL-----TVPDTITTWKTEAFCL-SSNGFGLA-PPALLTAFQPFFLELTLPYSII 812

  Fly   835 RGEVINVPALVFNYLPKTLDVEL--------TLDNEDQEYDFVDASN----------EVIGDQKR 881
            ||||..:.|.|||||.:.:.|::        ||::.||....:.|:.          .|||
Zfish   813 RGEVFELKATVFNYLSQCIKVQVTPTPSSNFTLNSLDQSSSTLVANGRKTFKWALTASVIG---- 873

  Fly   882 TQNIRVGANEAAGASFLIRPKVIGNILLKFKAISPLAG--DAIHKPLKVVPEGITQYQNRAFFIN 944
            |.|:.:.|.  |..|    .::.||.::..    |..|  |.:.:.|.|:.||:.:...|::.:.
Zfish   874 TVNVTISAQ--ANPS----QELCGNRVVTV----PSRGRIDIVTRSLLVLAEGVKRTFTRSWLLC 928

  Fly   945 LKD---TGEFKNTFELEVPEDVVPDSERVEFGLVGDLLGPVVKNLENLLRLPSGCGEQTMSKLVP 1006
            .|.   :.:.:.||    |::|:..|.|....::||::|..:|||.|||::|.|||||.|..|.|
Zfish   929 PKGSMLSEDARITF----PKNVIQGSARCSVSVIGDIMGRALKNLANLLQMPYGCGEQNMIILGP 989

  Fly  1007 NYLVRDYLKSIKKLTPALDTRIKRNLQDGYQHMLHYRHDDGSFSSFGPTKWRQEDPVRNGSTWLT 1071
            |..:..|||...:||||:.......||.|||..|:|||.|||||:||         ....:||||
Zfish   990 NIYILRYLKVTAQLTPAIQDTAMTYLQSGYQGQLNYRHSDGSFSTFG---------YDESNTWLT 1045

  Fly  1072 AYVLRSFSKIKDIIDLDEQILAKGYEFLLTRQAENGSFTEHGEYFYSSQR----SLLTLTANSLL 1132
            |:|:|:|...:....:|..:|....::|:::||.||.|.:.|..:::..|    ..:|:|...:.
Zfish  1046 AFVMRTFGLARSFTYIDPNVLQSAKDWLISKQASNGCFVQQGTLYHNDMRGGVGDNVTMTGYIVA 1110

  Fly  1133 ALLEEEKP-NQAAIDKAVAYLSANTAESIELLPKSIAIYALQKA-KAPEAAKQVASLKSLAKHED 1195
            ||||...| ....|.||:::|.............::..|....| :....|:.:.||::.|..|.
Zfish  1111 ALLEIGVPVTDPVITKALSFLRPLVGNLGNTYVTALLAYTFSLAGETSTRAQLLNSLRNTAISEG 1175

  Fly  1196 DRTWWTEDL--DKLRASKNCGRWWCWIWSQDVEITSYALLSLLDSDQET------ADSVLNTVRW 1252
            ....|::..  |.|.                |||::|.||::|.....|      |:.::|   |
Zfish  1176 TTLHWSQTTSGDTLA----------------VEISAYVLLAVLTVQPVTTANLGYANRIVN---W 1221

  Fly  1253 LIAQRNGFGGFASSQDTVVGLTALIKFAEKSGYEAAKWEVTVSNKGKREKTEKLNTSEENDLLLQ 1317
            |:||:|.:|||:|:|||||.|.|:..:|...........|||.:............:..|.||.|
Zfish  1222 LVAQQNPYGGFSSTQDTVVALQAMALYASLVFSSGGSSTVTVQSSVPAGDVYNFAVTPNNRLLYQ 1286

  Fly  1318 TV---EFPQGTKSLEFEAKGTGAAMVQISYQYNLVEKEPKP-------SFKIQTTVLPESSPANL 1372
            ..   .|| ||.|:  .|.|:....||::..||:    |.|       |...:.|...:.||.||
Zfish  1287 ESPLNNFP-GTYSV--VASGSTCVSVQVACFYNI----PTPVVVAKTLSVVAKVTGNCKGSPVNL 1344

  Fly  1373 ELSVCVDYVEEGESKESNMAILEVSLPSGYTADEDSFADIRNIE-RVRLVETKNGDSVVVIYFEN 1436
            .|:..|.|.  |....:||.::::.:.||:|||........|.. .|:.|:|: ||.|:| |.:.
Zfish  1345 MLTFTVKYT--GPKPTTNMLLVDIKVLSGFTADTSLLGSPPNFSPLVQRVDTE-GDRVLV-YLQE 1405

  Fly  1437 LAKNEEKCIRIEAYRTHAVANQKPSSVVLYDYYDTNKK-ATEYYSIKS 1483
            :.|.......|:..:|.||.|.||:.:.:||||..::. .|.|.|:.|
Zfish  1406 VPKGVPVTYSIQLTQTVAVKNLKPAVINVYDYYQRSESFETTYTSVCS 1453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep4	NP_001260590.1	A2M_N	126..219	CDD:280081	27/92 (29%)
		A2M_N_2	528..653	CDD:285005	39/148 (26%)
		A2M	768..859	CDD:278630	37/103 (36%)
		A2M_2	982..1279	CDD:239227	104/310 (34%)
		A2M_comp	1035..1281	CDD:284982	79/259 (31%)
		A2M_recep	1389..1479	CDD:284981	29/91 (32%)
LOC103909927	XP_009296557.2	A2M_N	144..235	CDD:307790	29/117 (25%)
		A2M_N_2	478..626	CDD:311575	41/166 (25%)
		A2M	748..836	CDD:306673	37/94 (39%)
		A2M_2	965..1248	CDD:239227	104/310 (34%)
		A2M_recep	1359..1448	CDD:311553	29/90 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	217	1.000	Domainoid score	I2610
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177369at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm6406
orthoMCL	1	0.900	-	-		OOG6_100452
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	6	5.820