Protein Alignment Tep4 and LOC100489060

DIOPT Version :9

• Sequence 1: NP_001260590.1
• Gene: Tep4 / 35248
• FlyBaseID: FBgn0041180
• Length: 1498
• Species: Drosophila melanogaster
• Sequence 2: XP_002938549.2
• Gene: LOC100489060 / 100489060
• -ID: -
• Length: 1482
• Species: Xenopus tropicalis
• Alignment Length: 1621
• Identity: 438/1621 - (27%)
• Similarity: 688/1621 - (42%)
• Gaps: 277/1621 - (17%)

  Fly     8 AVSLCVILALLQTMEPVKAEGKYTIVGPGTIHSHRDYNVAVAVHQTKEPVTLKVGITGPSYNKTE 72
            |::||::|......:|...:.:|.::.|..:|...:....:.:....|.||:.:.:..|:.|.|.
 Frog     5 ALTLCLLLTAFPGGDPAPPDPQYLLLVPTVLHGASEEKFCLLLSHLNETVTMTLTLYLPTQNHTL 69

  Fly    73 TVELATAGEFKQ-ITFKLPPLEAGEYNLTAEGVKG--LEFKNSTKLNWENFKPYIKIQTDKGKYK 134
            ..:..|..|... :||..|.||.....:....|:|  |.||:..|:..:..:..:.|||||..||
 Frog    70 LEKQVTEKEEDGCVTFMTPKLEVAAVAILTLDVQGDALHFKSQRKILIKPLQNPVFIQTDKPIYK 134

  Fly   135 PGDTINYRVIFLDENLRPDTAKDEVVVWFEDSKRNRIKQEKHIKTTGGVYTGKFELSEFATLGSW 199
            ||..:.:|:..||||..|.:.|.. .|:..|.:.|||.|..:::...|:....|:||...|||.:
 Frog   135 PGQKVQFRIASLDENFHPVSEKFP-AVYITDPQGNRISQWLNVELKKGLTQESFQLSSEPTLGIY 198

  Fly   200 SLHVQNGDQHHDGGIYFGGRKQFGGFGHRWHRSDELVNFEVEKYVLPKYSVKMDATQQVSVRDGE 264
            .|.|              ||::.....|         :|.||:||||||.|::.....|.:.|..
 Frog   199 KLTV--------------GREKSAPVTH---------SFSVEEYVLPKYEVQVKLPPVVGIMDKG 240

  Fly   265 FNVVLKANYTYGKPVNGKVLVNVHLDSTSSWENVDGKTVQTDYPGHSVVGTADMVGGKAKLTMDL 329
            ..|.:...|||||||.|::.|.|....:..:....|   :.|       |..:.:..:|......
 Frog   241 IKVTVCGRYTYGKPVLGRIKVRVCRKFSDRYNLCKG---EED-------GVCEEINHRAGPNGCF 295

  Fly   330 KDFAS-YLPHKTSSSY---AQITATVEEDFTGVKLNETGGVQLYPYRYEMSCTDYSSCFSFKPDK 390
            .:..| .:.....|.|   .:.:||:.||.|||:|......::.....::|.....|.:.
 Frog   296 SEVVSTRMFQMRRSGYEDKIRASATIIEDGTGVELTAAVSSEIKKTLAKVSFRHLDSHYR----- 355

  Fly   391 EHELNFKITYVDGSL-ITDTKSVVKAKFTEGIRRNYAFYAFGTDHQEPELPTIEKKTFVFESHLN 454
                  |...:.|.| :.|......|..|..|     |..:||:               |.....
 Frog   356 ------KGLPLFGQLFLEDASGNPMANETVVI-----FVGYGTN---------------FTYTTG 394

  Fly   455 ASGVAPFKVVLPDLPDIANFTRYYSIELEFVDEKRDLYTTYPYREPKQIENPSSEEEKEWFRAEV 519
            ..|.|.|      |.|.:|..:   ..|:.....::..:.|.||.............||::
 Frog   395 QDGTAEF------LIDTSNVQK---SSLQIRARYKEGESCYQYRWVSVSYQGDERSVKEFY---- 446

  Fly   520 QRPKDVWNLKIGQEYQVI--LNSSRPLKYFV---------------YNIVGRGNILETKRVDLAE 567
            .|.|..  |||...|:::  ....:.:.:|:               |.::.:|.|....|.::
 Frog   447 SRAKSY--LKIQPIYKILECQKQEKVIVHFILSAEGVGETTNAVFHYLVMSKGGIAGHGRHEI-- 507

  Fly   568 PQTTVNVTIKPTF---LT-----TPYGRVYFYYVDETGEFRYTEETFSVEVELQNQIEIK-APAE 623
             :.:.|.....||   ||     .|......|.:.|:||......:..||....|::|:. :|:|
 Frog   508 -EISPNQNASGTFWFRLTAGTDIAPSANFLVYLILESGEVIADSISLKVEKCFGNKVELSFSPSE 571

  Fly   624 VKPGADVALEIKTSPKSFVGLLAVDQSVLLLGSNNDLNKESFNWRLNGYDTSTPWQGGYSY---- 684
            ..|||...|.:.|:|.|...|.|||:|||:|....:|:.::....|...|.|     ||.:
 Frog   572 ALPGAPADLHLLTAPSSLCALRAVDESVLILKPEAELSAQTIYNLLPLQDLS-----GYIHDGNF 631

  Fly   685 ------------YPGERTGVVTMTNAYFFYNRTAPD-----YNILTEGFGGSSFA---MRKTTVA 729
                        .|....|:        :|..|.|:     |.|| :..|...|.   :|...|.
 Frog   632 LEELWDDPCIKMEPLFINGI--------YYMPTNPEWDTDTYTIL-KNLGLKVFTNARIRPPLVC 687

  Fly   730 HDSHVF-HSGAGGP------------TQA-VGFSAESASAS---------AAPV---VRKNFAET 768
            .....: |.|.|||            .|| :|..|..:.|.         |.||   |||.|.||
 Frog   688 GPRSFYEHYGTGGPFAVPMSLSAGMGVQAGMGVQAGMSGAGLHIGRNIPVAEPVIETVRKYFPET 752

  Fly   769 WIFADIESTEEEVFKWVKTIPDTITNWVVTGFSLHPQKGLGVTNDQTNIKTFQPFFVSVRLPYSV 833
            |::..:|:..:.......|:|||||.|....|......|.|: ::..::..|||||:.:.||||.
 Frog   753 WLWQLVETDADGKADLAVTVPDTITTWKAGMFCTSQGAGFGL-SETISLVAFQPFFLELTLPYSA 816

  Fly   834 KRGEVINVPALVFNYLPKTLDVELTLDNEDQEYDFVDASNEVIGDQKRTQNIRVGANEAAGASFL 898
            .|||:..:.|.|||||.:|:.|.:.|::.:|   |:....:|..|     ...|.||.....|:.
 Frog   817 IRGEIFTLKATVFNYLSQTIRVGILLEDSNQ---FLAKPTKVQED-----GYCVTANGQVTLSWE 873

  Fly   899 IRPKVIGNI-------------LLKFKAISPLAG--DAIHKPLKVVPEGITQYQNRAFFINLKDT 948
            :..|.:|.:             |.:.:.:||..|  |.|.|.:.|.|||:.:.:..:..|..|.:
 Frog   874 VTLKSLGEVNFTMSAETLNGEGLCENEIVSPAQGRKDTITKHIIVEPEGVKKEETHSTMICGKGS 938

  Fly   949 GEFKNTFELEVPEDVVPDSERVEFGLVGDLLGPVVKNLENLLRLPSGCGEQTMSKLVPNYLVRDY 1013
             |......|::||.||..|.|..|..|||:||..::||.||:::|.|||||.|....|...:.:|
 Frog   939 -EITENIPLKLPEKVVEGSARAYFSAVGDILGTAMQNLGNLVQMPYGCGEQNMVLFTPIIYISEY 1002

  Fly  1014 LKSIKKLTPALDTRIKRNLQDGYQHMLHYRHDDGSFSSFGPTKWRQEDPVRNGSTWLTAYVLRSF 1078
            |....:|||.:.::....:..|||..|.|:|.|||:|:||       .....|:|||||:.::||
 Frog  1003 LNKTNQLTPEMKSKTLSYMSTGYQKQLSYKHPDGSYSAFG-------QRYGEGNTWLTAFTMKSF 1060

  Fly  1079 SKIKDIIDLDEQILAKGYEFLLTRQAENGSFTEHGEYFYSSQR----SLLTLTANSLLALLEEEK 1139
            ::.:..|.::|:::.....:|..||..||.|...|:.|.::.:    ..:||.|...:||||...
 Frog  1061 ARARAHIYIEEKLITGALLWLSIRQKPNGCFHSVGKLFNNAMKGGVDDEVTLAAYITIALLEYPL 1125

  Fly  1140 P-NQAAIDKAVAYLSANTAESIELLPKSIAIYALQKAKAPEAAKQ-VASLKSLAKHED-----DR 1197
            | ....:..|:..|.:.......:..|::..||...|...:..:| :.||...|..:|     .|
 Frog  1126 PVTHPTVRNALFCLESALGGKNGIYTKALMAYAFTLAGRMDIRRQLLQSLDEQAIKKDGTVHLHR 1190

  Fly  1198 TWWTED--LDKL---RASKNCGRWWCWIWSQDVEITSYALLSLL------DSDQETADSVLNTVR 1251
            ..:::|  :|:.   ||.           |.:||:.||.||:||      |.|...|..|   |.
 Frog  1191 PEFSDDSGVDRFPYRRAP-----------SAEVEMNSYMLLALLSKHNVSDEDLTLATQV---VS 1241

  Fly  1252 WLIAQRNGFGGFASSQDTVVGLTALIKFAEKS-GYEAAKWEVTVSNKGKREKTEKLNTSEENDLL 1315
            |:|.|:|..|||:|:|||||.|.||..:...: .::|.:   |||....:....:.:..:.|.||
 Frog  1242 WMIKQQNPNGGFSSTQDTVVALQALSLYGSLTLSHDAMR---TVSLSLDKTPVAEFHVEDSNRLL 1303

  Fly  1316 LQTVEFPQGTKSLEFEAKGTGAAMVQISYQYNL-VEKEPKPSFKIQTTVLPES----SPANLELS 1375
            ||.:...:..........|:|...:|.:.:||: :.||..| |.|..|..||:    |.....:.
 Frog  1304 LQRIALKEVPGDYLATVSGSGCLYLQTTLRYNVPIPKEDAP-FTISVTTDPETCDRKSLKTFTIV 1367

  Fly  1376 VCVDYVEEGESKESNMAILEVSLPSGYTADEDSF----ADIRNIERVRLVETKNGDSVVVIYFEN 1436
            ..|.||  |:...||||::||.|||||...:.|.    |..|.|:|......:     |::|||:
 Frog  1368 ANVSYV--GKRLNSNMAVVEVKLPSGYIPIKPSVKKMTASNRLIQRAEAHANE-----VIVYFES 1425

  Fly  1437 LAKNEEKCIRIEAYRTHAVANQKPSSVVLYDYYDTNKKATEYYSIKSKLCDICEGDDCKSK 1497
            |.|:.:. .|....:...:.|.:|::||:||||:|:..|...|...      |...|..:|
 Frog  1426 LFKDIQS-FRFSVEQEIPIGNLQPATVVVYDYYETDDLAITKYDAP------CSAKDGANK 1479

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep4	NP_001260590.1	A2M_N	126..219	CDD:280081	31/92 (34%)
		A2M_N_2	528..653	CDD:285005	38/150 (25%)
		A2M	768..859	CDD:278630	33/90 (37%)
		A2M_2	982..1279	CDD:239227	101/318 (32%)
		A2M_comp	1035..1281	CDD:284982	84/267 (31%)
		A2M_recep	1389..1479	CDD:284981	33/93 (35%)
LOC100489060	XP_002938549.2	YfaS	<124..>1065	CDD:225248	283/1054 (27%)
		A2M_N	124..216	CDD:280081	35/115 (30%)
		A2M_N_2	455..600	CDD:285005	35/147 (24%)
		A2M	752..838	CDD:278630	32/86 (37%)
		A2M_2	971..1269	CDD:239227	101/318 (32%)
		A2M_comp	1023..1270	CDD:284982	84/267 (31%)
		A2M_recep	1379..1467	CDD:284981	33/93 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D177369at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010