Protein Alignment Tep4 and LOC100487726

DIOPT Version :10

• Sequence 1: NP_001260590.1
• Gene: Tep4 / 35248
• FlyBaseID: FBgn0041180
• Length: 1498
• Species: Drosophila melanogaster
• Sequence 2: XP_031758487.1
• Gene: LOC100487726 / 100487726
• XenbaseID: XB-GENE-29078871
• Length: 1413
• Species: Xenopus tropicalis
• Alignment Length: 1546
• Identity: 408/1546 - (26%)
• Similarity: 649/1546 - (41%)
• Gaps: 289/1546 - (18%)

  Fly    31 TIVGPGTIHSHRDYNVAVAVH-----QTKEPVTLKVGITGPSY-NKTETVELATAGEFKQITFKL 89
            |.|.||.       :..:|||     .::..||.::...|.|. |.::..:....|     ...:
 Frog    34 TFVIPGV-------STTLAVHWFGQNHSEITVTAEIWDNGISLANSSKVFQKDILG-----LLSI 86

  Fly    90 PPL----EAGEYNLTAEGVKGLE--FKNSTKLNWENFKPYIKIQTDKGKYKPGDTINYRVIFLDE 148
            |||    .:..|.:...|..|.|  |.|:..:..|.....:.|:|||..||||.|:..|:|.:..
 Frog    87 PPLSVISSSASYLIRVYGTAGNELLFSNNYTMQLETKNVSLLIETDKSAYKPGQTVKIRIISIRR 151

  Fly   149 NLRPDTAKDEVVVWFEDSKRNRIKQEKHIKTTGGVYTGKFELSEFATLGSWSLHVQNGDQHHDGG 213
            :|||......||:  .|.|.|.|||....|...||.|.:|.||..|..|:|.:|.:.
 Frog   152 DLRPYKGLVNVVI--RDPKSNIIKQWLQRKPELGVITEEFLLSVNAMAGTWRVHAET-------- 206

  Fly   214 IYFGGRKQFGGFGHRWHRSDELVNFEVEKYVLPKYSVKMDATQQVSVRDGEFNVV--LKANYTYG 276
                            ..::.:....|..:..||:.|.: .|....|...:.|::  :.||||||
 Frog   207 ----------------DMTENIEEISVIHFEHPKFDVTI-KTPSFYVDPKQQNLIGTVIANYTYG 254

  Fly   277 KPVNGKVLVNVHLDSTSSWENVDGKTVQTDYPGHSVVGTADMVGGKAKLTMDLKDFASYLPHKTS 341
            :||.|...|.:    ||.::......::..|   .:.|:||.....|:|        |.||   |
 Frog   255 RPVKGNATVLI----TSLYDIQAANGIKKTY---EMSGSADFTFTYAEL--------SRLP---S 301

  Fly   342 SSYAQITATVEEDFTGVKLNETGGVQLYPYRYEMSCTDYSSCFSFKPDKEHELNFKITYVDGSLI 406
            .....|||.|:|:.||:.::::..|:                   |.|.|:||  .|......||
 Frog   302 GLTLNITAVVKEELTGIAISKSSYVK-------------------KVDSEYEL--VIVSQPPVLI 345

  Fly   407 TDTKSVVKAK--------FTEGIRRN-------YAFYAFGTDHQEPELPT-------IEKKTFVF 449
            .....:.|.:        .|:|.|.|       .:|..:..:.:....||       :|    ..
 Frog   346 PGINFITKIQLQRKDRLHLTQGERENNISVKVTQSFMPWLVETEGVNTPTGATNLNYVE----TL 406

  Fly   450 ESHLNASGVAPFKVVLPDLPDIANFTRYYSIELEF--VDEKRDLYTTYPYREPKQIENPSSEEEK 512
            :.::..||:  ..|.||    :.|......||..:  :.:|..::.........||:.|.|.
 Frog   407 QYNIPESGI--ISVELP----LQNSVLLIIIEAVYQNITQKWQMHRDLGISSSAQIQLPDSP--- 462

  Fly   513 EWFRAEVQRPKDVWNLKIGQEYQVILNSSRPLKYFVYNIVGRGNILETKRVDLAEPQTTVNVTIK 577
                |:|..|.|| .:|...|.|.:        |:|  |:.||.|:      .||...:...|:.
 Frog   463 ----AQVGTPFDV-RVKTTPEIQNL--------YYV--IMARGIIV------AAEKTNSTTFTLT 506

  Fly   578 PTFLTTPYGRVYFYYVDETGEFRYTEETFSVEVELQNQIEIKAPAEVK-----------PGADVA 631
            |.:...|...:..|:::      :...:|.: ::....|:||...|.|           |..:|.
 Frog   507 PEYSWAPSAVLMVYFLN------FNNNSFEI-IQASRTIDIKGMFENKVSLSWSVTKTAPSENVR 564

  Fly   632 LEIK-TSPKSFVGLLAVDQSVLLLGSNNDLNKESFNWRLNGYDTSTPWQGGYSYYPGERTGVVTM 695
            |.:. |...|.|||..||.|..||.:.|.| ||.....:..|               .:..|.::
 Frog   565 LNVDITEAGSLVGLRVVDISDKLLSNGNHL-KEKVEAEMKSY---------------TKDFVNSL 613

  Fly   696 TNAYFFYNRTAPDYNILTEGFGGSSFAMRKTTVAHDSHVFHSGAGGPTQAVGFSAESASASAAPV 760
            |:....|:      .||.|.|....|.:|:                         |....:..|:
 Frog   614 TDGIISYD------GILLEEFIPELFIIRE-------------------------EIEPPANVPI 647

  Fly   761 VRKNFAETWIFADIESTEEEVFKWVKTIPDTITNWVVTGFSLHPQKGLGVTNDQTNIKTFQPFFV 825
            |   |.||||:.:...:.........|:|:.:|:|..:.|.:....|||:..:...::.|||||:
 Frog   648 V---FPETWIWLETNISSGIRTSLPVTVPNAVTSWTASAFVISDVLGLGLIEESVELQAFQPFFI 709

  Fly   826 SVRLPYSVKRGEVINVPALVFNYLPKTLDVELTLDNEDQEYDFVDASNEVIGDQKRTQNIRVGAN 890
            ::..||:|.|||...:..|::|.|.:.|.|.::|:. :..:|.:...|: .|.....:|:.:.:.
 Frog   710 TLNAPYAVTRGEQFILRVLLYNCLEENLQVNVSLET-NNAFDIIIPEND-NGAIPWLRNVSIRSK 772

  Fly   891 EAAGASFLIRPKVIGNILLKFKAISPLAGDAIHKPLKVVPEGITQYQNRAFFINLKDTGEFKNTF 955
            |:....|.:.||.:|...:..:|:|..|.|...:.:.|..||:..:..:...:.:..||......
 Frog   773 ESEIILFPVSPKQLGVNFITVRAMSRTASDIATQKILVKAEGVQNFYTQNLILEVNGTGSVSQQL 837

  Fly   956 ELEVPEDVVPDSERVEFGLVGDLLGPVVKNLENLLRLPSGCGEQTMSKLVPNYLVRDYLKSIKKL 1020
            ....|.:||..||:....:|||.|||.:|.||:|:|:|.|||||.|....|...|..||.|..:.
 Frog   838 SFTFPTNVVGGSEQASVSVVGDFLGPSIKGLESLIRMPYGCGEQNMINFAPIIYVLQYLTSTSQQ 902

  Fly  1021 TPALDTRIKRNLQDGYQHMLHYRHDDGSFSSFGPTKWRQEDPVRNGSTWLTAYVLRSFSKIKDII 1085
            |..:..|....::.|||..|:||..|.|||:||       |...:||:||:|:|:|.|.:.:..|
 Frog   903 TEDIRRRAISFMEQGYQSELNYRRGDDSFSAFG-------DRDSSGSSWLSAFVVRCFLQARTFI 960

  Fly  1086 DLDEQILAKGYEFLLTRQ-AENGSFTEHGEYFYSS-QRSL---LTLTANSLLALLEEEKPN---Q 1142
            ::..:||.:..|:|:.:| ..||.|.|.|..|.|. |..|   :||||..|.:|||..:.:   .
 Frog   961 NISPEILNRTVEWLIQQQDPVNGKFLEPGHVFNSRLQGGLNGPITLTAYVLTSLLENSQYSIHYA 1025

  Fly  1143 AAIDKAVAYLSANTAESIEL-LPKSIAIYALQKAKAPEAAKQVASLKSLAKHEDDRTWWTEDLDK 1206
            :.:.|||.||.......|.. ...|:..|||..|.:.:|:..:..|.|...:.|.:.:|:
 Frog  1026 SRVGKAVQYLEKEFEGGISSNYTLSVVAYALSVANSTKASAALTQLNSRTSNNDGQIYWS----- 1085

  Fly  1207 LRASKNCGRWWCWIWSQDVEITSYALLSLLDSDQETADSVLNTVRWLIAQRNGFGGFASSQDTVV 1271
              :......:| ...|.|:|..:|||||....:: .|:.| ..:.||:.|||..||::|:|||:|
 Frog  1086 --SPTGASNYW-QPPSADIETAAYALLSHCQQNR-IAEGV-PIMNWLVQQRNNLGGYSSTQDTIV 1145

  Fly  1272 GLTALIKF-AEKSGYEAAKWEVTVSNKGK-REKTEKLNTSEENDLLLQTVEFPQGTKS----LEF 1330
            .|.||.:| |.....:.....|:|:..|. ..|:.::.    ||.|| .|:..|...|    |..
 Frog  1146 ALWALAQFMAVAPSLKETSLTVSVTGPGPFAPKSFQIT----NDNLL-AVQIQQIDISYPIVLNV 1205

  Fly  1331 EAKGTGAAMVQISYQYN------LVEKEP-KPSFKIQTTVLPESSPANLEL---SVCVDYVEEGE 1385
            .|.|.|.|:.|::..||      ..:..| |.:|.:..|.....:  |.||   .:|..|  :|.
 Frog  1206 SAVGRGIAIFQLNGIYNKRVLPRRKQNTPNKEAFALSVTTTDVGN--NTELLYVDICSSY--QGT 1266

  Fly  1386 SKESNMAILEVSLPSGYTADEDSFADIRNIER---VRLVETKNGDSVVVIYFENLAKNEEKCIRI 1447
            ..|..|.:|:|...||:....      |.|..   :::|||| .|. |.:||:::..| ..|:.:
 Frog  1267 ENEVGMVLLDVGFLSGFKLHP------RGIPESGLLKMVETK-ADR-VYLYFDSMTTN-SVCVTV 1322

  Fly  1448 EAYRTHAVANQKPSSVVLYDYYDTNKKATEYYSIKS----KLCDICEGDDC 1494
            ...||..||..:...|.:.|||:....||..|:.::    .:||.| |.:|
 Frog  1323 PVVRTALVAGSREGIVTITDYYNPTNSATRTYNSETMKNLSICDFC-GSNC 1372

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep4	NP_001260590.1	YfaS	<76..1411	CDD:441940	368/1403 (26%)
		A2M_2	982..1279	CDD:239227	105/305 (34%)
		A2M_recep	1387..1480	CDD:462226	28/95 (29%)
LOC100487726	XP_031758487.1	YfaS	<131..1214	CDD:441940	336/1263 (27%)
		A2M_2	864..1153	CDD:239227	105/305 (34%)
		A2M_recep	1268..1355	CDD:462226	28/95 (29%)