Protein Alignment Tep4 and LOC100487578

DIOPT Version :10

• Sequence 1: NP_001260590.1
• Gene: Tep4 / 35248
• FlyBaseID: FBgn0041180
• Length: 1498
• Species: Drosophila melanogaster
• Sequence 2: XP_012809164.2
• Gene: LOC100487578 / 100487578
• XenbaseID: XB-GENE-29078815
• Length: 1437
• Species: Xenopus tropicalis
• Alignment Length: 1574
• Identity: 405/1574 - (25%)
• Similarity: 688/1574 - (43%)
• Gaps: 249/1574 - (15%)

  Fly     9 VSLCVILALLQTMEPVKAEGKYTIVGPGTIHSHRDYNVAVAVHQTKEPVTLKVGITGPSYNKTET 73
            :|:|:.:......||.:|....|:... .||..:: ...|.:.|.|..|:|::.:....:::...
 Frog     6 ISVCLSILDFGAAEPPQAHFMITVPAQ-LIHPSKE-EACVTLLQLKGAVSLRMELHRDDHHQVVA 68

  Fly    74 VELATAGEFKQ-ITFKLPPLEAGE----YNLTAEGVKGLEFKNSTKLNWENFKPYIK-IQTDKGK 132
            .:..|...|.. ..||:|..|...    ::::||| ..:.. |.||......:.|:. |||||..
 Frog    69 DDKITTESFTHCYPFKVPAAEEDREVWLFHVSAEG-DNINI-NQTKKVLIMEQMYVTLIQTDKPM 131

  Fly   133 YKPGDTINYRVIFLDENLRPDTAKDE--VVVWFEDSKRNRIKQEKHIKTTGGVYTGKFELSEFAT 195
            ||||..:|:||:.|.::..   |:|:  .:|...|...|||.|...:..|.|:....|.|:|...
 Frog   132 YKPGQIVNFRVVTLGKDFH---AQDDKYPLVELLDPNDNRIGQWLDVAPTQGIADFSFRLAEEVE 193

  Fly   196 LGSWSLHVQNGDQHHDGGIYFGGRKQFGGFGHRWHRSDELVNFEVEKYVLPKYSVKMDATQQVSV 260
            ||.:.:::.:.:                       ||.:  :|.|.:|||.::.|.:.|.:.||.
 Frog   194 LGRYKINIPSTE-----------------------RSSQ--SFIVAEYVLKRFKVDIHAQEDVSP 233

  Fly   261 RDGEFNVVLKANYTYGKPVNGKVLVNVHLDSTSSWE----NVDGKTVQTDYPGHSVVGTADMVGG 321
            .|..|::.:..:|||||||.|.:.:.|...:.:.|.    :.|.:..:...|  ::.|..|..|.
 Frog   234 TDDSFHLEVCGSYTYGKPVRGVMNITVFPLNIAWWRLYYGDFDREPTEELMP--TMQGRTDDRGC 296

  Fly   322 KAKLTMDLKDFASYLPHKTSSS---YAQITATVEEDFTGVKLNETGGVQLYPYRYEMSCTDYSSC 383
            ..| .:||.      |...|::   ...|.|.:.||.||  |.|:|.       :.:..||:.:.
 Frog   297 FTK-DIDLH------PFNVSTNPRVKIVILALLTEDNTG--LEESGS-------HFIEFTDHQTV 345

  Fly   384 FSFKPDKEHELNFKITYVDGSLITDTKSVVKAK-FTEGIRRNYAFY-AFGTDHQEPELPTIEKKT 446
            .....|..::.....|           .::||: .....|:|...| ....|..:..: |:|
 Frog   346 EFVNLDSYYQKGIPFT-----------GMLKARTLKREPRKNEKVYLVVNVDEVDTNI-TLE--- 395

  Fly   447 FVFESHLNASGVAPFKVVLPDLPDIANFTRYYSIELEFVDEKRDLYTTYPYREPKQIENPSSEEE 511
                  .:|:|:|.|.:...:..|:.:.|..:|:|     :..|::....:..|...|:.|
 Frog   396 ------TDANGIARFTLDTSEWNDMVSLTGKFSLE-----DGDDMFVALNWLFPFYSESNS---- 445

  Fly   512 KEWFRAEVQRPKDVWNLK--IGQEYQVILNSSRP----LKYFVYNIVGRGNILETK--RVDL--- 565
              :.:.:......:.:.|  :..||.:..|...|    |.:| |.::.:|.|:..|  :||:
 Frog   446 --FLKVQTVAEDLLCSTKQSVSVEYTIDKNELDPESDHLSFF-YILMSKGEIITNKEHKVDVPNL 507

  Fly   566 -AEP--QTTVNVTIKPTFLTTPYGRVYFYYVDETGEFRYTEETFSVEVELQNQIEIK-APAEVKP 626
             :.|  |.:.|:|........|...:..|.:...||.......:.|.|...|::::: ....|:|
 Frog   508 PSGPILQGSFNITFSVNVNLVPVATLLVYAIFPDGEVAADRARYRVPVCFDNKVQLEFTENNVRP 572

  Fly   627 GADVALEIKTSPKSFVGLLAVDQSVLLLGSNN----------------DLNKESFNWRLNGYD-- 673
            |.:|.|::|....|...:.:||:.:|||..:.                ::|:..|.:.:..::
 Frog   573 GGNVNLDVKADAGSLCSVRSVDKGLLLLQEHKTNEILSRVMGYYEYMFEINRRGFPYTIEDFEPY 637

  Fly   674 -----------------TSTPWQGG----YSYYPGERTGVVTMTNAYFFYNRTAPDYNILTEGFG 717
                             ...||...    ||.:......|.|.|..........|:|   |..|.
 Frog   638 PCLEDAPVLPNRAKRSIKRAPWYQSEADVYSLFKSSNLKVFTNTRIRKPVTCELPEY---TRRFS 699

  Fly   718 GSSFAMRKTTVAHDSHVFHSGAGGPTQAVGFSAESASASAAPVVRKNFAETWIFADIESTEEEVF 782
                             ...|.|...:.:. |..:|.||....|||.|.|||:: |:.|...:..
 Frog   700 -----------------IKDGVGAADRKLD-SPSTAPASKEHPVRKFFPETWLY-DLVSVGPQGK 745

  Fly   783 KWVK-TIPDTITNWVVTGFSLHPQKGLGVTNDQTNIKTFQPFFVSVRLPYSVKRGEVINVPALVF 846
            |.:. |.|.:||.||...|.: ...|.|..:| ..:|||||:|:.:.|||||.:.|...:.|||:
 Frog   746 KSLNLTAPHSITEWVTDAFCV-GNSGFGEVHD-IRMKTFQPYFIDLLLPYSVVQKEHFTLTALVY 808

  Fly   847 NYLPKTLDVELTL----DNEDQEYDFVDASNEVIGDQKRTQNIRVGANEAAGASFLIRPKVI--- 904
            |||...:.||:.|    |..:...| ::.|..:.|.:..:....:.|.:.....|.:..:.:
 Frog   809 NYLNHCVLVEVALTIPPDFGEPRTD-IEKSACICGQETASFTWNITATKLGTIPFKVTSRALHVE 872

  Fly   905 ---GNILL----KFKAISPLAGDAIHKPLKVVPEGITQYQNRAFFINLKDTGE-FKNTFELEVPE 961
               .:::|    |||      .||:.|.:.|.|.|:...:.....  |..||: .:....|.:|:
 Frog   873 GDCSDVVLDPETKFK------HDAVQKTILVKPSGVEVDKTHTSL--LCPTGDSVRGEISLVLPD 929

  Fly   962 DVVPDSERVEFGLVGDLLGPVVKNLENLLRLPSGCGEQTMSKLVPNYLVRDYLKSIKKLTPALDT 1026
            :||..|......::||::|.::.||.|||:||:|||||.|:...||..|.:||:|.|.|||.:..
 Frog   930 NVVEGSGHAHVTVLGDIMGNIISNLGNLLQLPTGCGEQNMALFAPNVYVLEYLESAKALTPEIKD 994

  Fly  1027 RIKRNLQDGYQHMLHYRHDDGSFSSFGPTKWRQEDPVRNGSTWLTAYVLRSFSKIKDIIDLDEQI 1091
            ::...|..|||..|.::||:|::|:||     ::|  ..|:|||||.|:|.|||.:..:.:||:.
 Frog   995 KVLNYLTTGYQRQLMFKHDNGAYSAFG-----KKD--EEGNTWLTAMVVRCFSKAQKTVFIDEKH 1052

  Fly  1092 LAKGYEFLLTRQAENGSFTEHGEYFYSSQRSL----LTLTANSLLALLEE-EKPNQAAIDKAVAY 1151
            :....::|.:.|.:||.|...|:.|.:..:..    :.::|...:||||. ...|.:.::.|:..
 Frog  1053 IQDAIKWLGSHQLDNGCFRSVGKLFNNGLKGAVDDEMAISAYITVALLEHGTVHNSSLVENALRC 1117

  Fly  1152 L--SANTAESIELLPKSIAIYALQKAKAPEAAKQVASLKSLAKHEDDRTWWTEDLDKLRASKNCG 1214
            |  :|||..:  ...::|..||.                :|:..:|.|....::|:|....:...
 Frog  1118 LKDAANTVNN--TYNEAILAYAF----------------TLSGDKDLRQHMLDELEKEVIEEGGS 1164

  Fly  1215 RWWCWIWSQDVEITSYALLSLLDSDQETADSV---LNTVRWLIAQRNGFGGFASSQDTVVGLTAL 1276
            :.|...||..|||:||.||:||..|:.|...:   .|.:.|:|.|:|.:|||.|:|||||.:.||
 Frog  1165 KHWSEQWSGAVEISSYVLLALLSGDEVTKKDLELSSNIISWVIKQQNPWGGFYSTQDTVVAVHAL 1229

  Fly  1277 IKFAEKSGYEAAKWEVTVSNKGKREKTEKLNTSEENDLLLQTVEFPQGTKSLEFEAKGTGAAMVQ 1341
            .|:|..:.:|.....:|| :.|......:.:..:.|.||||....|....:....|.|||...||
 Frog  1230 SKYARATYHEKRDVALTV-HSGLIGYQNRFHVDDSNRLLLQRAPLPDELGTYIITATGTGCVYVQ 1293

  Fly  1342 ISYQYNLVEKEPKPSFKIQTTVLPESSPA----NLELSVCVDYVEEGESKESNMAILEVSLPSGY 1402
            ...:|:....|....|.::.|..|::..|    :.|:.:.|.|  .|....:||.|::|...||:
 Frog  1294 GHLKYHTHPAESFQHFTLKVTTEPDNCTAEAERSFEIHMAVSY--SGNRATTNMGIIDVYHVSGF 1356

  Fly  1403 TADEDSFADIRNIERVRLVETKNGDSVVVIYFENLAKNEEKCIRIEAYRTHAVANQKPSSVVLYD 1467
            .....|...:...|.|:..|..  |..|.||.|.|. :|.:...|...:...|:|.:|::|::||
 Frog  1357 APVARSLKLLEKKENVKRTEVT--DEKVSIYLEELT-HETETFSIVVKQETPVSNLQPANVIVYD 1418

  Fly  1468 YYDTNKKA-TEYYS 1480
            |||..::| .||::
 Frog  1419 YYDPRERAEAEYHA 1432

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep4	NP_001260590.1	YfaS	<76..1411	CDD:441940	369/1435 (26%)
		A2M_2	982..1279	CDD:239227	104/306 (34%)
		A2M_recep	1387..1480	CDD:462226	30/93 (32%)
LOC100487578	XP_012809164.2	YfaS	<127..1426	CDD:441940	374/1441 (26%)
		A2M_2	951..1232	CDD:239227	104/305 (34%)