Protein Alignment Tep4 and cpamd8

DIOPT Version :10

• Sequence 1: NP_001260590.1
• Gene: Tep4 / 35248
• FlyBaseID: FBgn0041180
• Length: 1498
• Species: Drosophila melanogaster
• Sequence 2: XP_003201105.3
• Gene: cpamd8 / 100151400
• ZFINID: ZDB-GENE-050208-428
• Length: 1860
• Species: Danio rerio
• Alignment Length: 1832
• Identity: 450/1832 - (24%)
• Similarity: 717/1832 - (39%)
• Gaps: 501/1832 - (27%)

  Fly     7 FAVSLCVILALLQTMEPVKAEGKYTIVGPGTIHSHRDYNVAVAVHQTKEP--VTLKVGITGPSYN 69
            :.|.:|.:::.:.:.|   .:| |.|..|....:..:..|:|.:....|.  |.|::.:.|....
Zfish    14 WTVFMCGVMSGVHSQE---RQG-YLIAAPSVFRAGVEEAVSVTLFNMVEDTRVQLQLSVKGEIVA 74

  Fly    70 KTETVELATAGEFKQITFKLPPLEAGEYNLTAEGVK-----GLEFKNSTKLNWENFKPYIKIQTD 129
            .:.    .|..:...|..|:|....|:.:|...|.:     |..|:|.|.:..::....:.||||
Zfish    75 HSH----GTVRDKGTIKIKVPSDLRGQAHLKVWGNRQLNEGGYIFQNHTTVTIDSKGTTVFIQTD 135

  Fly   130 KGKYKPGDTINYRVIFLDENLRPDTAKDEVVVWFEDSKRNRIKQEKHIKT-TGGVYTGKFELSEF 193
            |..|||...:...|..:..:|:|.:.|.|  .:..|.:.:.|...|.:|: ..|:....|.||:.
Zfish   136 KPVYKPQQKVLINVYAVTPDLKPTSEKLE--AYIVDPRGSHIVHWKDLKSICCGIVNMSFPLSDQ 198

  Fly   194 ATLGSWSLHVQNGDQHHDGGIYFGGRKQFGGFGHRWHRSDELVNFEVEKYVLPKYSV-------- 250
            ...|.|.:.|:..                   ||.:::|     |||:|||:|::.:
Zfish   199 PVFGEWLVFVEMQ-------------------GHTYNKS-----FEVQKYVMPRFELIIVPPPYI 239

  Fly   251 -KMDATQQVSVRDGEFNVVLKANYTYGKPVNGKVLVNVHLDSTSSWENVDGKTVQTDYPGHSVVG 314
             .:::.:||:|         ||.||:||||:||:.||:         .|:|........||.||.
Zfish   240 RDLNSCEQVTV---------KARYTFGKPVSGKLTVNM---------TVNGVGYYRHEVGHPVVK 286

  Fly   315 TADMVGGKAKLTMDLKDFASYLPHKTSSSYAQITATVEEDFTG-----VKLNET-GGVQLY---- 369
            :.: :.|.|..::.:||              .:...|.:.|.|     |.:|.. ||.|..
Zfish   287 SME-IKGSASFSLCVKD--------------MMPIEVTDHFRGAVNMWVTVNSVDGGQQTMFDDS 336

  Fly   370 -PYRYEMSCTDYS--SCFSFKPDKEHELNFKITYVDGSLITDTKSVVKAKFTEGIRRNYAFYAFG 431
             |...::....||  :...|||...::...::||.|||........|||:.|
Zfish   337 TPVHKQLIDIKYSKDTRKQFKPGLPYKGMIEVTYPDGSPAEGVHVRVKAELT------------- 388

  Fly   432 TDHQEPELPTIEKKTFVFESHL-NASGVAPFKVVLPDLPDIANFTRYYSIELEFVDEK--RDLYT 493
                        .|..|:.|.| :.:|.|.|::  |.:|..|.:. :...::..:|.|  .|.|.
Zfish   389 ------------PKDNVYTSELVSKNGKATFEI--PSIPTAAQYV-WLESKVTAIDGKPAGDQYL 438

  Fly   494 TYPYREPKQIENPSSEEEKEWF---RAEVQRPKDVWNLKIGQEYQVILNSSRPLKYFV-YNIVGR 554
                        |:......|:   :..:|.......|.||||.::.|.|:.|..:.: |.|..|
Zfish   439 ------------PNYLSITSWYSPSKCHIQLLSPSAPLMIGQEAEIFLKSTCPCNFTLHYEIASR 491

  Fly   555 GNILET------------KRVDLAEPQTTVNVTIKPT------------------FLTT----PY 585
            |||:::            ||..:.. .|.::.|.||.                  |..|    |.
Zfish   492 GNIVQSGQRHTNSTTHREKRATITF-DTNIHTTAKPQQDSDSSQAEMDSCVSVLHFNVTPPMAPL 555

  Fly   586 GRVYFYYVDETGEFRYTEETFSVEVELQNQIEIK-APAEVKPGADVALEIKTSPKSFVGLLAVDQ 649
            .|:..|||.|.||.........|:...:|:|.:. :..|..||:.::|::|....|.|.:.:||:
Zfish   556 SRLLVYYVRENGEGVTDSLQLPVQSRFENEISVSLSTNESMPGSPISLKVKAESGSCVCVASVDK 620

  Fly   650 SVLLLGSNNDLNKESFNWRLNGYDTS----TPWQGGYSYYPG----------------------- 687
            |:.||.....|..|.....|..:|.|    .|...|:.::||
Zfish   621 SMYLLKPGFQLTPEKVFKDLAEFDVSDAFGVPKDEGHFWWPGLSSRRRRSSVFPWHWDITKDARF 685

  Fly   688 --ERTGVVTMTNAYFFYNRTAPDYNILTEGFGGSSFAMRKTTVAHDSHVFHSGAGGPTQAVGFSA 750
              ..||:|.||:.....:|.:          ||  ....:...|...|         |..:..:.
Zfish   686 AFTETGLVVMTDMVSLNHRQS----------GG--MYTDEAVPAFQPH---------TSTLVAAM 729

  Fly   751 ESASASAAPVVRKN-FAETWIF--ADIESTEEEVFKWVKTIPDTITNWVVTGFSLHPQKGLGVTN 812
            .|.|.:.|...|:. |.||||:  .::.|...|. :....|||:||.||.....|..:||||:..
Zfish   730 HSRSGTRAENRRRTFFPETWIWHCFNVSSLNGEA-ELHLDIPDSITTWVTEAIGLSAEKGLGLAR 793

  Fly   813 DQTNIKTFQPFFVSVRLPYSVKRGEVINVPALVFNYLPKTLDV---------------------- 855
             ...::||:|||:...||||:.|||...||..|:||||...:|
Zfish   794 -TAELRTFKPFFIDFTLPYSIVRGEQTKVPLTVYNYLPTCSEVHVKVSVPKGIKFVGHPGKHHLT 857

  Fly   856 --------------------ELTLDN---------------------------EDQE------YD 867
                                ||...|                           |:||      .|
Zfish   858 RKKCVAPGEATPTFIVLLFSELVSANITARAVAYSEPSCCSDGLQSSKASKAGEEQEDRSPVGMD 922

  Fly   868 FVDASNEVIGD---QKRTQNIRVGANEAAGAS--------FLIRPKVIGNILLKFK-------AI 914
            :|..|..|..:   ::.|.::....||....|        ::.:|..:.::.:..|       |:
Zfish   923 YVRRSVLVEPEGLPREYTYSVFFCPNERIHISTPNKYEYQYVKKPAKVTHVQVAIKSHNDAHIAL 987

  Fly   915 SPLAGDA----------------------IHKPLKVVP-EGITQYQN-RAFFINLK--------- 946
            ||.|.|:                      :.:|:...| .||..:.. |:|:|:.:
Zfish   988 SPSAHDSTEMVEIVLGGRQNSRSWISRGKMGEPVVSTPTPGILSWDEFRSFWISWRGGGVQVGHG 1052

  Fly   947 ------------------------------DTGEFK------------NTFELEVPEDVVPDSER 969
                                          ..|||:            ..|.|.||.:|||.|||
Zfish  1053 LEPSSETTILQLAGPLTSQVRHIGFSTGWGSIGEFRIWRKEDADENHNEAFTLGVPHNVVPGSER 1117

  Fly   970 VEFGLVGDLLGPVVKNLENLLRLPSGCGEQTMSKLVPNYLVRDYLKSIKKLTPALDTRIKRNLQD 1034
            ....::||::||.:.||:.|||||.|||||.|....||..|..||:...:|:..::......|..
Zfish  1118 ATAAMIGDVMGPTLNNLDKLLRLPFGCGEQNMIHFAPNVFVLKYLQKTHQLSLEVEAEATDYLLQ 1182

  Fly  1035 GYQHMLHYRHDDGSFSSFGPTKWRQEDPVRNGSTWLTAYVLRSFSKIKDIIDLDEQILAKGYEFL 1099
            |||..|.|:..|||:|:||     :.|  .:||.||||:||:||::.:..|.:|.:.|.....:|
Zfish  1183 GYQRQLTYKRQDGSYSAFG-----ERD--SSGSMWLTAFVLKSFAQSRGFIFIDPEELHAAKSWL 1240

  Fly  1100 LTRQAENGSFTEHGEYFYSSQR----SLLTLTANSLLALLE-----EEKPNQAAIDKAVAYLSAN 1155
            ::.|.:.|||...|.......:    ..::|||..::||:|     ||:  ..|:.||.|:|.:|
Zfish  1241 ISNQKDEGSFPAMGRILNKDLQGGIHGKISLTAYVVVALMETGITTEEE--NVAVAKAKAFLESN 1303

  Fly  1156 TAESIELLPKSIAIYALQKAKAPEAAKQVASLKSLAKHEDDRTWWT--------EDL-----DKL 1207
            |..:.:....:::.|||...::|.|...:..|..:|..:|..|.|:        ||.     |.|
Zfish  1304 TYSADDPYTTALSAYALTLLRSPYAPLALRRLNHMAITQDGFTHWSLTGRTETDEDTFMGFSDGL 1368

  Fly  1208 RASKNCGRWWCWIWSQDVEITSYALL--SLLDSDQETADSVLNTVRWLIAQRNGFGGFASSQDTV 1270
            ..|         :.|.:||:|:|.||  :||..    ..|.|..|:||..|||..|||:|:|||.
Zfish  1369 SQS---------VVSAEVEMTAYGLLTYTLLGD----VASALPVVKWLSQQRNALGGFSSTQDTC 1420

  Fly  1271 VGLTALIKFAEKSGYEAAKWEVTVSNKGKREKTEKLNTSEENDLLLQTVEFPQGTKSLEFEAKGT 1335
            |.|.||.::|..|........:::::. ..:..|......:|..:||....|.....|...|||.
Zfish  1421 VALQALSEYAILSYVGGVNLTISLAST-NLDFQETFELQWDNKKILQKAVIPSIPTGLFVSAKGE 1484

  Fly  1336 GAAMVQISYQYNLVEKEPKPSFKIQTT---------VLPES------------------------ 1367
            |..::||...||:.:...||:|:::..         :||.|
Zfish  1485 GCCLMQIDVSYNVPDPVAKPAFQLKVDLKEPRQEQHILPSSRHISPRTRSRADNRSELTRKRRAP 1549

  Fly  1368 ----SPA--------NLELSVCVDYVEEGESKESNMAILEVSLPSGYTADEDSFADIRNIERVRL 1420
                .||        .:.|.||..::..|   .||||:|||.|.||:.||.:|...:...:||.|
Zfish  1550 VDDEDPAGHQDHLDYRVTLEVCTRWLHVG---SSNMAVLEVPLLSGFRADIESLERLLLDKRVGL 1611

  Fly  1421 VETKNGDSVVVIYFENLAKNEEKCIRIEAYRTHAVANQKPSSVVLYDYYDTNKKATEYYSI--KS 1483
            ...:.....|:.||:.:......|:...|.|.:.|....|..|.:||||:...:||.:|::  .|
Zfish  1612 KRYEVDGRKVLFYFDEIPSQCMTCVAFNAVREYIVGKTAPVPVKVYDYYEPAFEATRFYNVSESS 1676

  Fly  1484 KLC-DICEGDDC 1494
            .|. ::|:|..|
Zfish  1677 PLARELCDGTTC 1688

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tep4	NP_001260590.1	YfaS	<76..1411	CDD:441940	413/1673 (25%)
		A2M_2	982..1279	CDD:239227	109/320 (34%)
		A2M_recep	1387..1480	CDD:462226	31/92 (34%)
cpamd8	XP_003201105.3	None