DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ref(2)P and sqst-2

DIOPT Version :9

Sequence 1:	NP_001014491.1	Gene:	ref(2)P / 35246	FlyBaseID:	FBgn0003231	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_501171.2	Gene:	sqst-2 / 189791	WormBaseID:	WBGene00021495	Length:	242	Species:	Caenorhabditis elegans

Alignment Length:	202	Identity:	43/202 - (21%)
Similarity:	72/202 - (35%)	Gaps:	62/202 - (30%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 YLRMPSQNYTILRREIELYLFQER-------QLPKCDVRTFWIDA--------------DKDEIE 65
            |.|.||  |:.:.|:|.:..:...       .|.|.:.....|:|              ....|.
Worm    16 YERTPS--YSTIPRDIHVSFYHNNYHRSKILYLNKFNAMEKLIEAAHELYPSNGVYRLFSDSTIG 78

  Fly    66 IVNQNDYEIFLAKCESN-------MHVQVAPLAPVEEPKATKQEGSSANAEAPSVDDPSNFTIHD 123
            ..|:.:..:.:.:|..|       :|:::...    .|::..:.....|  .|.:..||..:||.
Worm    79 AQNELNDSVQVMECVQNPDHILPHLHIRLEDY----RPRSISRNYHEVN--VPIIRTPSQHSIHQ 137

  Fly   124 AVE-------------------------CDGCGLAPLIGFRYKCVQCSNYDLCQKCELAHKHPEH 163
            :|.                         |..| ...::|.||.|:||.:||:|..||....|.||
Worm   138 SVRFNDNKRHHHHHHHDSIRNFVHHDTPCRNC-FRIIVGSRYHCLQCPDYDICGDCEKDLVHYEH 201

  Fly   164 LMLRMPT 170
            .:||:.|
Worm   202 ALLRIVT 208

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ref(2)P	NP_001014491.1	PB1	6..88	CDD:295447	16/93 (17%)
		ZZ	121..165	CDD:278966	19/68 (28%)
		UBA_SQSTM	555..593	CDD:270505
sqst-2	NP_501171.2	ZZ_NBR1_like	166..206	CDD:239080	17/40 (43%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157576
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4582
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275680at2759
OrthoFinder	1	1.000	-	-		FOG0002104
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR15090
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.940