Protein Alignment ref(2)P and C06G3.6

DIOPT Version :9

• Sequence 1: NP_001014491.1
• Gene: ref(2)P / 35246
• FlyBaseID: FBgn0003231
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_501086.1
• Gene: C06G3.6 / 177467
• WormBaseID: WBGene00015552
• Length: 498
• Species: Caenorhabditis elegans
• Alignment Length: 491
• Identity: 98/491 - (19%)
• Similarity: 171/491 - (34%)
• Gaps: 148/491 - (30%)

  Fly    30 YTILRREIELYLFQERQLPKCDVRTFWID----ADKDEI-EIVNQ--------------NDYEIF 75
            |..:|.|:..|   ..|||:..:....:|    |..|:: ..||:              .|.||
 Worm    83 YNNIRPELSFY---HSQLPQLFLHVRILDVSVIAKLDDLGRTVNECKATMKSDKAWRVMKDTEI- 143

  Fly    76 LAKCESNMHVQVAPLAPVEEPKATKQEGSSANAE--APSVDDPSNF---TIHDAVECDGCGLAPL 135
               .|..:.:|........|.|:.:::.|....|  ....:|.::|   .:|:| .||.| ...:
 Worm   144 ---AEGQLSLQELLDKQQLEIKSLQKDISEMKLENQCRKKEDKNSFKNKEVHEA-SCDKC-QDLI 203

  Fly   136 IGFRYKCVQCSNYDLCQKCELAHKHPEHLMLRMPTNN----------GPGMVDAWFTGPGLGRRS 190
            ||.|:||..|.|||||:.||.|..|.:|.::|:.:.|          .|..|
 Worm   204 IGHRFKCAICYNYDLCETCEAAGVHAQHALIRLVSENTLFPEHLIVKNPEEV------------- 255

  Fly   191 GRRSRGHCPFQETNQADPAGEPARDSRRERRQARRHAGVLTQFVEMMTNLP--LNTTTATAPAE- 252
                      ::.|....|...:||  |..:...|..|:..|.:....|:.  ||..:.....|
 Worm   256 ----------KDQNGQVQAIASSRD--RAIQVPLRRLGITPQAIATKNNVSRYLNAQSDRNIIED 308

  Fly   253 --------PQKPKAAEQTESPPQAEPTVTAEKA------------AESEAKPTEPKKVNTDQSVP 297
                    .:||:..|:..  |:.:.|...:|.            |||.....| |::..|.|..
 Worm   309 PWYAQHMSSRKPQTYERMH--PKLKDTTDGKKVQKVSFRDRFYKKAESSLDKHE-KQLRFDLSAS 370

  Fly   298 RTE----------DPVTTPRSTQPTTPVINLDNISQIVPPEYMSAGIEILNNFSEMFSKIIDTTE 352
            |.|          :..|..:..:....::..:.|:......:.|      :.|..:|:|:.|..:
 Worm   371 RQEFIREKEKFRVEKETLMKQKEQIEEMMKQETINFETNRAFFS------DRFEPIFNKVKDGKK 429

  Fly   353 GGDSGIFAPSTTPSAENKKPEEQGQSSGQSGASSANQSAVPSAAPSANQSNVPSANQSATPSISG 417
            ..|      .||     :|.|.:.:::                     :||.|.:..|...|:|.
 Worm   430 SED------DTT-----RKVEFEVETA---------------------ESNYPGSIFSDEDSLSD 462

  Fly   418 ------SIPDAQLETEPLNPKPSETTTETEQERRRS 447
                  .|.:.:..:|..:.:..:.....|:|.::|
 Worm   463 LAEILKDIEEYECSSESSDDQEKDDFDVVEEEAKQS 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ref(2)P	NP_001014491.1	PB1	6..88	CDD:295447	17/76 (22%)
		ZZ	121..165	CDD:278966	21/43 (49%)
		UBA_SQSTM	555..593	CDD:270505
C06G3.6	NP_501086.1	ZZ_NBR1_like	194..236	CDD:239080	20/43 (47%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160157578
Domainoid	1	1.000	53	1.000	Domainoid score	I7600
eggNOG	1	0.900	-	-		E1_KOG4582
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S7489
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1275680at2759
OrthoFinder	1	1.000	-	-		FOG0002104
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15090
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	7	6.890