Protein Alignment CG10166 and DPM1

DIOPT Version :9

• Sequence 1: NP_609980.1
• Gene: CG10166 / 35240
• FlyBaseID: FBgn0032799
• Length: 241
• Species: Drosophila melanogaster
• Sequence 2: NP_001303963.1
• Gene: DPM1 / 8813
• HGNCID: 3005
• Length: 295
• Species: Homo sapiens
• Alignment Length: 271
• Identity: 177/271 - (65%)
• Similarity: 210/271 - (77%)
• Gaps: 35/271 - (12%)

  Fly     6 HKYSILMPTYNEKDNLPIIIWLIVKYMKASGLEYEVIVIDDGSPDGTLDVAKDLQKIYGEDKIVL 70
            :|||:|:|||||::|||:|:||:||....||:.||:|:|||||||||.|||:.|:||||.|:|:|
Human    25 NKYSVLLPTYNERENLPLIVWLLVKSFSESGINYEIIIIDDGSPDGTRDVAEQLEKIYGSDRILL 89

  Fly    71 RPRGSKLGLGTAYIHGIKHATGDFIVIIDADLSHHPKFIPEFIKLQQEGNYDIVSGTRYAGNGGV 135
            |||..|||||||||||:|||||::|:|:|||||||||||||||:.|:|||:||||||||.|||||
Human    90 RPREKKLGLGTAYIHGMKHATGNYIIIMDADLSHHPKFIPEFIRKQKEGNFDIVSGTRYKGNGGV 154

  Fly   136 FGWDFKRKLI-----------------------------------SRGANFLSQVLLRPNASDLT 165
            :|||.|||:|                                   |||||||:|:||||.|||||
Human   155 YGWDLKRKIISDGVLPCCPGWSLLGSSDPAILASWDYRCEPPRLASRGANFLTQILLRPGASDLT 219

  Fly   166 GSFRLYKKDVLEKCIASCVSKGYVFQMEMLVRARQHGYTIAEVPITFVDRIYGTSKLGGTEIIQF 230
            ||||||:|:||||.|..||||||||||||:|||||..|||.||||:||||:||.|||||.||:.|
Human   220 GSFRLYRKEVLEKLIEKCVSKGYVFQMEMIVRARQLNYTIGEVPISFVDRVYGESKLGGNEIVSF 284

  Fly   231 AKNLLYLFATT 241
            .|.||.|||||
Human   285 LKGLLTLFATT 295

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10166	NP_609980.1	PLN02726	3..241	CDD:215385	175/269 (65%)
		DPM1_like	10..237	CDD:133062	169/261 (65%)
DPM1	NP_001303963.1	PLN02726	23..295	CDD:215385	175/269 (65%)
		DPM1_like	29..291	CDD:133062	169/261 (65%)
		GVQW	175..206	CDD:290611	5/30 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165147572
Domainoid	1	1.000	285	1.000	Domainoid score	I1628
eggNOG	1	0.900	-	-		E1_COG0463
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H2865
Inparanoid	1	1.050	382	1.000	Inparanoid score	I2060
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG61609
OrthoDB	1	1.010	-	-		D1445102at2759
OrthoFinder	1	1.000	-	-		FOG0003124
OrthoInspector	1	1.000	-	-		oto91832
orthoMCL	1	0.900	-	-		OOG6_100818
Panther	1	1.100	-	-	LDO	PTHR43398
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4337
SonicParanoid	1	1.000	-	-		X2989
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	16	15.800