Protein Alignment CG10132 and LOC100489685

DIOPT Version :10

• Sequence 1: NP_609979.2
• Gene: CG10132 / 35239
• FlyBaseID: FBgn0032798
• Length: 1361
• Species: Drosophila melanogaster
• Sequence 2: XP_031752100.1
• Gene: LOC100489685 / 100489685
• XenbaseID: XB-GENE-29079839
• Length: 1146
• Species: Xenopus tropicalis
• Alignment Length: 1263
• Identity: 241/1263 - (19%)
• Similarity: 419/1263 - (33%)
• Gaps: 400/1263 - (31%)

  Fly   241 LGATLGTPMLPLTIESQDFTSVLGTASEEERL---LLEKWYTID-NSYQPMCHRLHAQQVDPYSS 301
            :|...|...||..||.::|..:| .|:||.|:   .||.||..| |...|..|.|..::..||:.
 Frog    13 IGEEYGQFSLPWKIEGEEFEKIL-LAAEESRISTRSLETWYLRDENGVPPAYHLLEKEEGLPYTQ 76

  Fly   302 -----------QVNGELNELLAVLLRL------FSDDVKDSYLTTVVEQEINNTVLMSQE----L 345
                       .:..|:.::|.|.:.|      .|....:.|..:.:|:|:   :...|:    :
 Frog    77 TNRRGATDPPPMIYQEIRKVLDVAVPLCVQQGSISPQQAEKYFRSALEEEL---LFALQDRPRAV 138

  Fly   346 AKRCI----------WIQTGSQVARPSENASPLELEVQRRLSHVYSGLKSQLSEKNLIRLLPT-- 398
            .:|||          ::|     .|.||:...:......:|.||.......|::...:.|..|
 Frog   139 HERCICYIHRVPYKAYLQ-----RRKSEHGETVRPRSYAKLCHVRDVFIPTLAQHGPLCLYSTTT 198

  Fly   399 -----MSILDEELSAVIESLLDK---TLAGIFEEHQQKNSIPYNTLGVDR---VLLEELRLVGHY 452
                 :...:|:....|:.|..:   .:.|:.|:     .:|.:.|....   ..::.|.|...|
 Frog   199 TCNIKVGYTEEKQEKYIDGLCTQFYSDILGLIEK-----DVPASPLYCSNRTGEAMQHLSLCSMY 258

  Fly   453 SKLLAQNSANFDIMNDVKRYI-RDSTAQPLVVSGARGSGKSVLVSKIMENVHRWKPEAQ--LILR 514
            :.|   ....|.....:..|| ...:.:|:||.|..|.||:||::...:.||.|.....  |::|
 Frog   259 ASL---QQFRFREEQTIHDYIVHGKSPKPMVVFGRSGCGKTVLLASCAKKVHSWLETCDPILVVR 320

  Fly   515 YANLSARSSDLTSLLGSMANQMSVLETGHQCQVPHTLEGYSRVIREILD-----RQQRFFVLIID 574
            :.........|:.|||.:..|:|.:   :|..:|..|:..:.:.:..:|     .:|...:||||
 Frog   321 FICPFREPLHLSRLLGGLCYQLSDI---YQRVIPSHLDDVAELRQCFVDLISLSSKQAPLILIID 382

  Fly   575 GVDELQRDELLDWLPQQLGS-AKMILTVSELADEGEDVDGTEAGDSFDMLAALAQLGIPQRCFLR 638
            .||.:.    :||||..:.. .|:|::|....:...|...::....|..|...     |||
 Frog   383 DVDHVP----IDWLPSPIPKFTKIIVSVKHQQNVISDQVKSQNKGQFLFLEIK-----PQR---- 434

  Fly   639 LRQFTERQWHDILS-----SGGGDFYAANGALKLPDDWKTLHGKTPYHAKSLWWLA--WLGHVAQ 696
             |:..:...|.:|.     :.|...| .|.:|:.        ..:|.....|:.|.  |..|...
 Frog   435 -RECNDNLKHCLLGCYRKITSGQQMY-VNRSLET--------NTSPLQVHLLFKLVAEWKSHQDV 489

  Fly   697 PISEIG----DISSRILQVLESKFATDQVELLLLIVRLSPWGIRESDCLGVFQKMTQLEAQVAFK 757
            ....:|    :.:.|:...||.|:..:.|...|..:.||..||      ||.:.:..|.|...
 Frog   490 DNQTLGEDTYEAAERLFHKLEIKYGREIVSRTLSYITLSQSGI------GVTELVDLLTADDL-- 546

  Fly   758 VWSKF-------------CWLMGPMLLGLKNIRIAD-------------KSFGRAVLARYAQK-- 794
            |..||             .|::..:||.|:.. :||             :.:.:.::.||...
 Frog   547 VLEKFHELFGTENIPRIPDWIVTGILLDLQGC-LADRMSAGCKLVYWNNRMYQQVIMTRYLSSPE 610

  Fly   795 ---------------QWLV------------------------HEALRDYFDRQD-------SEF 813
                           :|..                        |...|.|.|.|.       :..
 Frog   611 TVQELHTAMYYFFSGRWTCGKFISKAVQKFKSLLPNRRLANNNHTPNRHYLDYQPPSQPWFYNVL 675

  Fly   814 KGSQGANTYNYQKYLKLPYH-------------HFCAV------------------IED------ 841
            ...|.|.|.|.:|.|:||:|             .|.|.                  |||
 Frog   676 PVCQRAVTGNVRKALELPFHLKECGKLEKLYNEVFMAFPYYKVLVQAGQLHLLLNSIEDAAGIMG 740

  Fly   842 ------------------NPAPHKIDILFN------CFYFTDLQWIANKVHATGPEHLLNDILQA 882
                              ...|..::::|.      ...:..|..||.:||..|..:....:|.:
 Frog   741 KQELYFLYDMLKEVSCLLKEKPDSLEMIFQSKMLPLVLTYPPLSRIATQVHGEGRRNSTIKVLHS 805

  Fly   883 EWLAKSGGENCPTAYVH-------ICFLKQFLEQYLHELSYDGQQFYTLMKYYLKTRFREAPELK 940
            ..:      ..|...::       :..|:......|..:..:|..:...:...|..||:.:..:|
 Frog   806 PLI------TVPLFKIYFPEVSSVVRVLEMESNMQLMVVFGNGSVYTWAVGKNLALRFQGSVHIK 864

  Fly   941 D---DEKIRSWWEYTNELEFAFLEILN-ADLDAENGNQAEQEKPSDDAVPSSVPVKGYDVLMNLP 1001
            |   :.|.|.....|....|.||:.:: ..|:                          :::.|:.
 Frog   865 DVAVENKSRYLALCTMNHSFIFLDCVSWTTLN--------------------------NLMKNVN 903

  Fly  1002 QPGCYVASMCTDRSEICIWDVKNCCRIRELQGIQQPTAMCPVGNYEAAVLCRREIRVINLD-EGK 1065
            :.| .:...|:......:...:|.|.:| :.|:       |.|.....:....||..|:.| .||
 Frog   904 ENG-LIPKHCSFSETGLMVGFENSCTVR-IFGV-------PSGELIEEMTFPHEITFISCDNRGK 959

  Fly  1066 FKVTLKGVMNQKMPYFGLHDQNHL-------VCLSRNRMY--------VNLMNLESGDCV-TTFK 1114
            :.|.      ::|.:..::|....       |.|.:|.:|        |.::...|...| ..|.
 Frog   960 YTVM------EQMNHIVIYDNQDFSAKISLPVDLIKNTVYNIHIHESLVYIIGKASNISVWGIFN 1018

  Fly  1115 AGEDRFLNSLLVSGD-GRILVCGDETQKPFPLL-------VWHLSQRKLLYDLRIPHHDFITSLS 1171
            ..:.|.|:.|...|| |.::  ..|...|:.|.       |||....: .:..:.||...:|
 Frog  1019 PAQPRLLDELYSEGDYGEVV--STEYSPPWLLTCRAKYIEVWHTESWE-RHCFKPPHGKMLT--- 1077

  Fly  1172 AITHEGSYVCVVAKELNEPTTPNFIVVYDLQSGTLFKKWKPACNTVSLAISQVNACVIAGLEDAK 1236
                    .||.::...|                                      |||.:|:..
 Frog  1078 --------FCVFSQSCEE--------------------------------------VIAAVENLP 1096

  Fly  1237 IL-IWDLVTGNCKS---------TLIGH 1254
            .| :|:..:|.|.|         :::||
 Frog  1097 FLFVWNRESGQCISRLYLELATVSMVGH 1124

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10132	NP_609979.2	AAA_22	474..599	CDD:379165	36/132 (27%)
		WD40 repeat	1039..1072	CDD:293791	9/33 (27%)
		WD40	<1042..1321	CDD:441893	48/248 (19%)
		WD40 repeat	1079..1114	CDD:293791	8/50 (16%)
		WD40 repeat	1122..1160	CDD:293791	10/45 (22%)
		WD40 repeat	1167..1252	CDD:293791	13/94 (14%)
		WD40 repeat	1258..1294	CDD:293791
LOC100489685	XP_031752100.1	AAA_22	285..>392	CDD:379165	31/113 (27%)