Protein Alignment Hasp and F13b

DIOPT Version :10

• Sequence 1: NP_001137842.2
• Gene: Hasp / 35238
• FlyBaseID: FBgn0032797
• Length: 1677
• Species: Drosophila melanogaster
• Sequence 2: NP_112441.2
• Gene: F13b / 14060
• MGIID: 88379
• Length: 669
• Species: Mus musculus
• Alignment Length: 691
• Identity: 177/691 - (25%)
• Similarity: 273/691 - (39%)
• Gaps: 160/691 - (23%)

  Fly    70 STECPRDEEQATLLGQ------KCLRKC----------SSDE-----------DCKSKKK----- 102
            :||..:.|||.....:      :|.:||          |:|:           .|.|..|
Mouse    65 ATESGKQEEQIRCTAEGWSPNPRCYKKCLKPDLRNGYVSNDKVLYKLQERMSYGCSSGYKTTGGK 129

  Fly   103 -----KCLCDGVCGN-SCIKPDREC--PELAQPSLGQVTVAGRHFGAR--ASYACPHGYH-VVGL 156
                 .||..|.... ||.|....|  |||..   |..:...|.|..:  .:|.|..||: ..|.
Mouse   130 DEEVVHCLSAGWSSQPSCRKEQETCLAPELEH---GNYSTTQRTFKVKDIVAYTCTAGYYTTTGK 191

  Fly   157 QS--RLCQADGNWAGAEPACKQNIYCLKPPQIEHARNSALPEQETFDLDSTVQYHCHTGYVTNGF 219
            |:  ..|||:| |: ..|.|.: :.|.....||:....  |.::|::....||:.||..|..:|.
Mouse   192 QTGEAECQANG-WS-LTPQCNK-LMCSSLRLIENGYFH--PVKQTYEEGDVVQFFCHENYYLSGS 251

  Fly   220 PRAKCLAIDNLASWYGPDIQCEPR--SCGQPPDPAYGW---HAGECYTYGCKITYNCGTGYELVG 279
            ...:|...    .||.....||.|  .|..||.|....   |: ..|.:|.::...|...:.:.|
Mouse   252 DLIQCYNF----GWYPESPICEGRRNRCPPPPVPLNSKIQPHS-TTYRHGERVHIECELNFVIQG 311

  Fly   280 KHERYCQSDGSWTPKELPTCV-LVTSVVCPTPENPKNGKA-TYTTLAYN-SVVSYECRYGYTLVG 341
            ..|..|: :|.||  |.|.|: ....|.|..|.:.:||.| .::.:.|: ..|:|.|..||:|.|
Mouse   312 SEELLCE-NGKWT--EPPKCIEEKEKVACEQPPSVENGVAHPHSEIYYSGDKVTYRCGGGYSLRG 373

  Fly   342 ESSSRCGADRKWSGTL-PTCKE--INCGHPGVLYNG-WIENIEAGTGLGASIIFRCQPEMMINGL 402
            .|:..|...| |  || |.|.|  .||..|..:.|| .::.:.|....|:|:.:||....::.|.
Mouse   374 SSTITCNRGR-W--TLPPECVENIENCKPPPDIANGVVVDGLLASYTTGSSVEYRCNEYYLLKGS 435

  Fly   403 GSSVCQIDGRWRNALPECLAPCVVPTISQGNVYPIEIITDENGTTIVHPPTTTTQSPTQTQSIGG 467
            .:|.|: .|.| ::.|.||.||.: .:...|...|::.....|
Mouse   436 ETSRCE-QGAW-SSPPVCLEPCTI-DVDHMNRNNIQLKWKYEG---------------------- 475

  Fly   468 VEKVKHGTALEVKCDENY----EFPVSLLSPPTCNNGTWSIIPRCVPARCKSM-PRPP--KHGMV 525
              |:.||..::..|.:.|    ..|:|.:| ..||.|... .|.|:....|.| ..||  ::|.:
Mouse   476 --KILHGDLIDFVCKQGYNLSPSIPLSEIS-AQCNRGDVR-YPMCIRKESKGMCASPPVIRNGDI 536

  Fly   526 M--APKT-EHGMKARFKCKDGFKLVSPEGKDVTDPHDYVLTCSFGNWTGETPKCDEVFCSFPGYI 587
            :  |.:| |:|....::|.|...|...:.          :.|..|.|| ..|.|.|. |:. .::
Mouse   537 VSSAARTYENGSSVEYRCFDNHFLQGSQN----------VYCVDGVWT-TPPSCLEP-CTL-SFV 588

  Fly   588 PNGK--VLLVGNMGLYDYRPYVKKIVNNKQIMYDCDK-GYVLEVGPPGAT----CVGGKWRPLDL 645
            ...|  :.|..|   :|.||.   |::.:.|.:.|.: .|:.|....|:.    |..|:   |..
Mouse   589 EMDKNYLQLKWN---FDNRPL---ILHGEYIEFMCKRDAYISETSIAGSVLRVQCDRGR---LKY 644

  Fly   646 PQCLLGQHPRLRWNRRRRRSLQIRQLRSMYLLQRQRQLQRQ 686
            |:|.         .|.||.|.|       ..|:.:||::::
Mouse   645 PKCT---------PRDRRLSFQ-------EALRTRRQMEKR 669

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hasp	NP_001137842.2	CCP	121..175	CDD:153056	19/60 (32%)
		PHA02927	182..421	CDD:222943	72/250 (29%)
		PHA02927	<497..>654	CDD:222943	42/169 (25%)
		PHA02927	<946..1111	CDD:222943
		CCP	1408..1462	CDD:153056
		PHA02927	<1488..1643	CDD:222943
F13b	NP_112441.2	PHA02927	51..268	CDD:222943	53/214 (25%)
		PHA02927	165..452	CDD:222943	88/304 (29%)
		CCP	275..329	CDD:153056	16/57 (28%)
		CCP	525..579	CDD:153056	15/64 (23%)