Protein Alignment Hasp and CR1L

DIOPT Version :10

• Sequence 1: NP_001137842.2
• Gene: Hasp / 35238
• FlyBaseID: FBgn0032797
• Length: 1677
• Species: Drosophila melanogaster
• Sequence 2: NP_783641.1
• Gene: CR1L / 1379
• HGNCID: 2335
• Length: 569
• Species: Homo sapiens
• Alignment Length: 564
• Identity: 140/564 - (24%)
• Similarity: 213/564 - (37%)
• Gaps: 115/564 - (20%)

  Fly   140 GARASYACPHGYHVVGLQ-SRLCQADGNWAGAEPACKQNIYCLKPPQIEHARNSALPEQETFDLD 203
            |...:|.|..||.  |.. |.:|..:..|..|:..||:. .|..||...:.....:.:   ....
Human    58 GTYLNYECRPGYS--GRPFSIICLKNSVWTSAKDKCKRK-SCRNPPDPVNGMAHVIKD---IQFR 116

  Fly   204 STVQYHCHTGYVTNGFPRAKCLAIDNLASWYGPDIQCEPRSCGQPPDPAYGWHAG---ECYTYGC 265
            |.::|.|..||...|...|.|:...|...|......|:...||.||..|.|....   |.:.||.
Human   117 SQIKYSCPKGYRLIGSSSATCIISGNTVIWDNKTPVCDRIICGLPPTIANGDFTSISREYFHYGS 181

  Fly   266 KITYNCGTG------YELVGKHERYCQSD----GSWTPKELPTCVLVTSVVCPTPENPKNG---K 317
            .:||:|..|      :||||:...||.|.    |.|: ...|.|::...  | ||.|.:||   .
Human   182 VVTYHCNLGSRGKKVFELVGEPSIYCTSKDDQVGIWS-GPAPQCIIPNK--C-TPPNVENGILVS 242

  Fly   318 ATYTTLAYNSVVSYECRYGYTLVGESSSRCGADRKWSGTLPTCKEINCGHPGVLYNGWIENIEAG 382
            ...:..:.|.||.:.|:.|:.:.|.|..:|.|..||...||:|..:....|.||:....:..:..
Human   243 DNRSLFSLNEVVEFRCQPGFGMKGPSHVKCQALNKWEPELPSCSRVCQPPPDVLHAERTQRDKDN 307

  Fly   383 TGLGASIIFRCQPEMMINGLGSSVCQIDGRWRNALPEC-LAPC--VVPTISQGNV-YPIEIITDE 443
            ...|..:.:.|:|...:.|.....|...|.|..|.|.| :..|  .:..:..|:| :|:.:
Human   308 FSPGQEVFYSCEPGYDLRGSTYLHCTPQGDWSPAAPRCEVKSCDDFLGQLPNGHVLFPLNL---- 368

  Fly   444 NGTTIVHPPTTTTQSPTQTQSIGGVEKVKHGTALEVKCDENYEFPVSLLSPPTC----NNGTW-S 503
                                        :.|..::..|||.::...|  |...|    ....| |
Human   369 ----------------------------QLGAKVDFVCDEGFQLKGS--SASYCVLAGMESLWNS 403

  Fly   504 IIPRCVPARCKSMPRPPKHGMVMAPKTEH-GMKARFKCKDGFKLVSPEGKDVTDPHDYVLTCSFG 567
            .:|.|....|:: |..|.:|||......| |.:..:.|..|.:|:.....:.      :|:.:..
Human   404 SVPVCERKSCET-PPVPVNGMVHVITDIHVGSRINYSCTTGHRLIGHSSAEC------ILSGNTA 461

  Fly   568 NWTGETPKCDEVFCSFPGYIPNGKVLLVGNMG--LYDYRPYVKKIVNNKQIMYDC----DKGYVL 626
            :|:.:.|.|.::||..|..|.||:     :.|  |.|. ||      .|::.|.|    |:|...
Human   462 HWSMKPPICQQIFCPNPPAILNGR-----HTGTPLGDI-PY------GKEVSYTCDPHPDRGMTF 514

  Fly   627 E-VG---------PPGATCVGGKWRPLDLPQCLL----GQHPRL 656
            . :|         |.|    .|.|.. ..|:|.|    |.|..|
Human   515 NLIGESTIRRTSEPHG----NGVWSS-PAPRCELPVGAGSHDAL 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Hasp	NP_001137842.2	CCP	121..175	CDD:153056	10/35 (29%)
		PHA02927	182..421	CDD:222943	70/255 (27%)
		PHA02927	<497..>654	CDD:222943	45/182 (25%)
		PHA02927	<946..1111	CDD:222943
		CCP	1408..1462	CDD:153056
		PHA02927	<1488..1643	CDD:222943
CR1L	NP_783641.1	PHA02927	35..287	CDD:222943	70/238 (29%)
		PHA02927	284..541	CDD:222943	66/314 (21%)