| Sequence 1: | NP_523602.2 | Gene: | Top3alpha / 35236 | FlyBaseID: | FBgn0040268 | Length: | 1250 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_013335.1 | Gene: | TOP3 / 850935 | SGDID: | S000004224 | Length: | 656 | Species: | Saccharomyces cerevisiae |
| Alignment Length: | 656 | Identity: | 242/656 - (36%) |
|---|---|---|---|
| Similarity: | 349/656 - (53%) | Gaps: | 64/656 - (9%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 26 MKYLNVAEKNDAAKTIAGLLSNGAAQRREGYSVYNKVFD-----FEAPVRGQNAKMVMTSVSGHM 85
Fly 86 MQLAFQVSYKNWRTVDPRSLFDAPVKKGVGSDYEPIKRTLEREVRGCQGLIIWTDCDREGENIGY 150
Fly 151 EIIDVCR---AIKPNISVYRATFSEITTVAVRRALQQLGQPDKRQSDAVDVRTELDLRTGAAITR 212
Fly 213 FQTMRLQRLF---------------PEKIADKLISYGSCQIPTLGFVAERYKEIEAFVSEPFWKI 262
Fly 263 KVLHTIDDL--TVEFNWARNRLFDKEACENYLLLCLAEPDPRALVESVTVKPKHKWRPTPLDTVE 325
Fly 326 MEKLGSRKLKLSAKETMTIAEKLYTKGFISYPRTETNQFSKEFALAPLVEMQT--------GHRD 382
Fly 383 WGAFAQRVIEWGPN----------PRNGNKSDQAHPPIHP-TKLA--ENLQGNEARVYELVVRHF 434
Fly 435 LACVSKDAVGSETLVHIDIAGEKFTANGLVIHERNYLDVYVYDKW-SAKQIHHYENGQRFEPTEV 498
Fly 499 SLHEGATTAPPLLTEADLIALMEKHGIGTDATHAEHINTIKERGYI---GVLDKGFLVPGVIGMG 560
Fly 561 LYEGYDA--MELALAKPQLRAEFELDLKLICQGQKDPKVVLTEQIAKYKQAYQ----------QI 613
Fly 614 TDKITA 619 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Top3alpha | NP_523602.2 | TopA | 27..618 | CDD:223624 | 240/652 (37%) |
| TOPRIM_TopoIA_TopoIII | 27..185 | CDD:173782 | 58/165 (35%) | ||
| TOP1Ac | 194..608 | CDD:238110 | 179/457 (39%) | ||
| zf-C4_Topoisom | 657..694 | CDD:279704 | |||
| YrdD | 658..>744 | CDD:223625 | |||
| zf-GRF | 1033..1076 | CDD:284302 | |||
| zf-GRF | 1150..1193 | CDD:284302 | |||
| TOP3 | NP_013335.1 | TopA | 2..640 | CDD:223624 | 238/639 (37%) |
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C157343315 | |
| Domainoid | 1 | 1.000 | 286 | 1.000 | Domainoid score | I245 |
| eggNOG | 1 | 0.900 | - | - | E1_COG0550 | |
| Hieranoid | 1 | 1.000 | - | - | ||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 1 | 1.050 | 307 | 1.000 | Inparanoid score | I483 |
| Isobase | 1 | 0.950 | - | 0.919607 | Normalized mean entropy | S1204 |
| OMA | 1 | 1.010 | - | - | QHG62408 | |
| OrthoFinder | 1 | 1.000 | - | - | FOG0000966 | |
| OrthoInspector | 1 | 1.000 | - | - | oto99522 | |
| orthoMCL | 1 | 0.900 | - | - | OOG6_101027 | |
| Panther | 1 | 1.100 | - | - | LDO | PTHR11390 |
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 1 | 1.030 | - | avgDist | Average_Evolutionary_Distance | R1537 |
| SonicParanoid | 1 | 1.000 | - | - | X3214 | |
| TreeFam | 1 | 0.960 | - | - | ||
| 15 | 14.740 | |||||